Navigation Links
Scientists to study the role genes play in treating TB
Date:10/25/2012

The University of Liverpool has been awarded funding to determine whether differences in our genes determine how patients respond to drugs used to treat Tuberculosis (TB) in Sub-Saharan Africa.

Professor Andrew Owen, from the University's Department of Molecular and Clinical Pharmacology, is part of an international research team that will explore why some patients respond positively to anti-TB drug treatment while in other patients the treatments fail or the patients experience toxicity. In patients with HIV/AIDS the percentage of patients that are not cured by therapy is even higher.

TB is the second leading cause of death from an infectious disease worldwide after HIV/AIDS. In 2010 there were 8.8 million new cases of TB and 1.1 million deaths, including 350,000 deaths from TB among people with HIV. In Sub-Saharan Africa TB poses a major public health problem and is the leading killer of people living with HIV, causing one quarter of all deaths.

Professor Owen said: "There is a much greater understanding of genes which affect how we react and respond to drugs used in other diseases such as HIV than there is for TB. This project will study the genes of patients being treated with the four main anti-TB drugs, and also with a new drug which is in development, using clinical trial sites in Benin, Senegal and South Africa. The study aims to explore and determine genetic differences which affect the effectiveness and reaction to anti-TB drugs. It is funded through the H3Africa project which is led by African scientists and one of its aims is to foster capacity-building for research in Sub Saharan Africa."

The standard treatment for TB is a six-month course of four drugs taken daily for two months, followed by two drugs taken for a four-month period but as many as 10 per cent of patients do not respond to this treatment. Patients who have been treated with anti-TB drugs have an increased risk of spreading a strain of TB th
'/>"/>

Contact: Sarah Stamper
sarah.stamper@liv.ac.uk
01-517-943-044
University of Liverpool
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Kessler Foundation scientists awarded New Jersey grants for brain injury research
2. Scientists Focus on Factors Behind Asthma Attacks
3. Einstein-Montefiore scientists awarded 2 NCI Provocative Questions grants
4. Leading stem cell scientists to focus on diabetes, eye diseases at Cedars-Sinai symposium
5. Diets High in Fructose May Harm Liver in Some, Scientists Warn
6. Cardiff scientists bid to develop anthrax vaccine to counteract world bioterrorism threat
7. Scripps Research Institute scientists show protein linked to hunger also implicated in alcoholism
8. Scientists Spot 5 Genes That Help Shape Faces
9. Eight scientists honored in first annual Golden Goose Awards
10. Scientists Map Genetic Blueprint of Heart
11. Scientists use sound waves to levitate liquids, improve pharmaceuticals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Deer Path of Huntley -- a BMA affordable assisted living ... p.m. to 4 p.m. on Feb. 13. , The community, which ... with physical disabilities between the ages of 22 and 64. , ... sweetheart-themed karaoke. , For more information about the event or Deer ...
(Date:1/22/2015)... 2015 The City of West Hollywood hosted a ... commemorate the 42nd anniversary of the Supreme Court decision Roe v. ... 42 years since the Roe vs. Wade decision and the fight ... as ever,” said City of West Hollywood Councilmember Abbe Land. “We ...
(Date:1/22/2015)... VogueQueen is a seasoned and trusted leader who consistently delivers ... to have it lead the wedding dress industry into the ... dresses for the global market. , “The CEO of VogueQueen ... focuses on continuing the goal of operational excellence and giving ...
(Date:1/22/2015)... the premier women’s dress supplier, has recently released its ... of AngelWeddingDress.com to find more details. , Many ... a bridal party. AngelWeddingDress offers a variety of gorgeous ... wedding dresses are specially designed for 2015. , AngelWeddingDress ...
(Date:1/22/2015)... 2015 Thousand of GranuFlo lawsuits ( ... its GranuFlo and NaturaLyte dialysis concentrates continue to move ... District Court, District of Massachusetts, Bernstein Liebhard LLP reports. ... has remanded a case filed by the state of ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4
... -- A daily dose of vitamin D may just be ... to researchers at Loyola University Chicago Marcella Niehoff School of ... when days are short and more time is spent indoors. ... the nutrient,s widely reported health benefits," said Sue Penckofer, PhD, ...
... screen time in youth means trouble by mid-40s, despite activity levels, ... watch more television in their 20s and 30s are more apt ... their mid-40s than people who spent less time in front of ... enough for many, the worse news is that you can,t exercise ...
... , ... ... ... ...
... , ... ... ... ...
... , ... ... ... ...
... breast cancer surgery have a greater risk of the ... report Dana-Farber Cancer Institute scientists. The study, which ... who had breast cancer, found that those who started ... were more likely to have a local recurrence than ...
Cached Medicine News:Health News:Vitamin D lifts mood during cold weather months 2Health News:You Can't Exercise Away TV's Toll on the Heart 2Health News:You Can't Exercise Away TV's Toll on the Heart 3Health News:Inverness Medical Innovations Declares Dividend on its Series B Convertible Perpetual Preferred Stock 2Health News:Inverness Medical Innovations Declares Dividend on its Series B Convertible Perpetual Preferred Stock 3Health News:Seattle Sutton's Healthy Eating Sponsoring The Biggest Loser Chicago Casting Call 2Health News:Seattle Sutton's Healthy Eating Sponsoring The Biggest Loser Chicago Casting Call 3Health News:Seattle Sutton's Healthy Eating Sponsoring The Biggest Loser Chicago Casting Call 4Health News:AUA Foundation Responds to American Cancer Society Guideline for the Early Detection of Prostate Cancer 2Health News:AUA Foundation Responds to American Cancer Society Guideline for the Early Detection of Prostate Cancer 3Health News:Delaying post-surgical radiation increases risk of breast cancer recurrence in older women 2
(Date:1/23/2015)... 23, 2015 For the pharmaceutical industry, marketplace success is ... Likewise, the importance of the managed markets function - which ... grow as payer formularies and provider networks play an increasingly ... the same time, managed markets leaders must continually identify the ...
(Date:1/23/2015)... , Jan. 23, 2015 Research and Markets ... the "Urinary Catheters Market (Indwelling or Foley Catheters, ... Global Industry Analysis, Size, Share, Growth, Trends and Forecast ... , At present, the global market for ...
(Date:1/23/2015)...  MedScope ( www.medscope.org ), the leading provider of medical ... Connected World magazine Connected World Award for its ... be used anywhere, anytime. The nomination was made by ... nominating MedScope, Landon Garner , Director of Marketing ...
Breaking Medicine Technology:As Payer Influence Rises, Pharmaceutical Companies work to Optimize the Managed Markets Function 2Urinary Catheters Market (Indwelling or Foley Catheters, Intermittent Catheters and Male External or Condom Catheters) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Urinary Catheters Market (Indwelling or Foley Catheters, Intermittent Catheters and Male External or Condom Catheters) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3MedScope Nominated by RacoWireless for Prestigious 2015 Connected World Magazine Connected World Award 2
... LIUZHOU CITY, China , July ... CNBI), ("China BCT" or the,"Company"), a leading pharmaceutical distributor, retail pharmacy, ... , today,announced that the Financial Industry Regulatory Authority (FINRA) confirmed,the Company,s ... 2010 . , , ...
... LAUDERDALE, Fla. , July 27 OmniComm Systems, Inc. (OTC: ... of operations for the first half of fiscal 2010.   , ... New contracts for OmniComm products and ... 51% increase over first half of 2009.  Software as a Service (SaaS) ...
Cached Medicine Technology:FINRA Confirms China BCT's Corporate Name Change 2FINRA Confirms China BCT's Corporate Name Change 3OmniComm Systems, Inc. Announces 2010 First Half Results 2OmniComm Systems, Inc. Announces 2010 First Half Results 3OmniComm Systems, Inc. Announces 2010 First Half Results 4
CleanBox DNA workstation with two 254nm UV lambs & 12-hr timer, 90cm (36-inch)width, single door, 115V (w/crating)...
... highthroughput reading of tube racks. Its camera-based vision ... one second per rack, making it ideal for ... the reader allows a rack to be read ... arms. An optical safety switch prevents a rack ...
... Polypropylene workbench top with powder-coated ... from 25"-34". Available in hundreds ... include shelves, drawers, light fixtures ... an expert in custom building ...
Perforated or Rod Top, Free Standing or Wall Mounted, Storage Cubby Optional, Polypropylene Construction...
Medicine Products: