Navigation Links
Scientists to study the role genes play in treating TB
Date:10/25/2012

The University of Liverpool has been awarded funding to determine whether differences in our genes determine how patients respond to drugs used to treat Tuberculosis (TB) in Sub-Saharan Africa.

Professor Andrew Owen, from the University's Department of Molecular and Clinical Pharmacology, is part of an international research team that will explore why some patients respond positively to anti-TB drug treatment while in other patients the treatments fail or the patients experience toxicity. In patients with HIV/AIDS the percentage of patients that are not cured by therapy is even higher.

TB is the second leading cause of death from an infectious disease worldwide after HIV/AIDS. In 2010 there were 8.8 million new cases of TB and 1.1 million deaths, including 350,000 deaths from TB among people with HIV. In Sub-Saharan Africa TB poses a major public health problem and is the leading killer of people living with HIV, causing one quarter of all deaths.

Professor Owen said: "There is a much greater understanding of genes which affect how we react and respond to drugs used in other diseases such as HIV than there is for TB. This project will study the genes of patients being treated with the four main anti-TB drugs, and also with a new drug which is in development, using clinical trial sites in Benin, Senegal and South Africa. The study aims to explore and determine genetic differences which affect the effectiveness and reaction to anti-TB drugs. It is funded through the H3Africa project which is led by African scientists and one of its aims is to foster capacity-building for research in Sub Saharan Africa."

The standard treatment for TB is a six-month course of four drugs taken daily for two months, followed by two drugs taken for a four-month period but as many as 10 per cent of patients do not respond to this treatment. Patients who have been treated with anti-TB drugs have an increased risk of spreading a strain of TB th
'/>"/>

Contact: Sarah Stamper
sarah.stamper@liv.ac.uk
01-517-943-044
University of Liverpool
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Kessler Foundation scientists awarded New Jersey grants for brain injury research
2. Scientists Focus on Factors Behind Asthma Attacks
3. Einstein-Montefiore scientists awarded 2 NCI Provocative Questions grants
4. Leading stem cell scientists to focus on diabetes, eye diseases at Cedars-Sinai symposium
5. Diets High in Fructose May Harm Liver in Some, Scientists Warn
6. Cardiff scientists bid to develop anthrax vaccine to counteract world bioterrorism threat
7. Scripps Research Institute scientists show protein linked to hunger also implicated in alcoholism
8. Scientists Spot 5 Genes That Help Shape Faces
9. Eight scientists honored in first annual Golden Goose Awards
10. Scientists Map Genetic Blueprint of Heart
11. Scientists use sound waves to levitate liquids, improve pharmaceuticals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... July 14, 2014 Reha Technology ... a compact, portable and full-featured upper extremity robotic ... use of interactive games and challenges in a ... Occupational Therapy , Armotion combines a ... order to maximize the therapy effect for patients ...
(Date:7/14/2014)... Love Digits LLC has successfully launched ... The App brings ancient astrology to the modern dating ... compatibility using a five-star rating system. By entering their ... test their compatibility for love and marriage across seven ... five-star rating system generates a weighted average of the ...
(Date:7/14/2014)... 14, 2014 New research and analysis ... for the Earth examines toxic ingredients in tampons, ... nationwide, including specific chemicals that may be found in ... fragrances that may put women’s health at risk. ... Alexandra Scranton , the potential impact of toxic ...
(Date:7/13/2014)... Recently, MagicQuinceaneraDresses.com, a well-known special occasion dress manufacturer and ... Dama dresses . Furthermore, the company’s sales manager has ... sale. They are available at greatly discounted prices, up ... to unveil the cheap, fashionable Dama gowns. “By launching ... for our fans. It will last until July 26. ...
(Date:7/13/2014)... Manchester United and AS Roma ... International Champions Cup. The 2014 ICC is one of ... of the talent of it brings in. Teams like Real ... compete in the 2014 event spread across 10 American cities. ... game between Olympiacos and Milan and will conclude with the ...
Breaking Medicine News(10 mins):Health News:Reha Technology Launches the Armotion™, a Device for the Rehabilitation of the Upper Extremity 2Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 2Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 3Health News:New Patent Analysis Shows Toxic Risk From Tampons 2Health News:New Patent Analysis Shows Toxic Risk From Tampons 3Health News:New Patent Analysis Shows Toxic Risk From Tampons 4Health News:New Patent Analysis Shows Toxic Risk From Tampons 5Health News:Fashionable Dama Dresses Unveiled By Well-known Supplier MagicQuinceaneraDresses.com 2Health News:Manchester United vs. AS Roma Tickets in Denver, CO at Sports Authority Field at Mile High: Ticket Down Slashes Ticket Prices on International Champions Cup in Denver 2Health News:Manchester United vs. AS Roma Tickets in Denver, CO at Sports Authority Field at Mile High: Ticket Down Slashes Ticket Prices on International Champions Cup in Denver 3
... A novel drug designed to lessen muscle damage from a ... Clinical Research Institute. Results of the study, available online and ... journal Circulation, reflect the first time the drug has been ... blocks the activity of an enzyme called delta protein kinase ...
... HILL, N.C., Feb. 7 Selecting and deploying,cross- ... new,challenge for marketing leaders at pharmas and biotechs. ... similar,structure, composition, and responsibilities -- all detailed in ... Practices, LLC., According to research findings, most ...
... Research Proves Dance Dance ... Be a Tremendous Workout, SAN DIEGO, Feb. 7 ... hand controllers in favor of more,full-body interaction, the American Council ... The ACE commissioned research out of the University of ...
... Health Advocates Together to Educate ... Feb. 7 Most Americans are aware of,the dangers of ... says levels of indoor air pollution can be two to ... than outdoor air,pollution levels? Five out of 10 Americans are ...
... Videos of sports-fanatic pets sought for Mutt Madness contest, ... on to find,America,s "Ulti-mutt" Sports Pet. Video submissions and ... contest sponsored by PetFirst,Healthcare., If Fido is a ... your,football team scores or catches some serious air when ...
... already shown to improve health, can also cut total health-care ... of Washington. The study appears in the February issue of ... about 3 million older adults in the United States and ... mostly due to an increased use of medical, not mental ...
Cached Medicine News:Health News:Novel compound may lessen heart attack damage 2Health News:Pharmaceutical Product Commercialization & Governance Best Practices: Securing Talent for Highly-Effective Brand Teams 2Health News:Can a Video Game Make Your Kids More Fit? 2Health News:February is Designated as 'National Care About Your Indoor Air' Month 2Health News:February is Designated as 'National Care About Your Indoor Air' Month 3Health News:February is Designated as 'National Care About Your Indoor Air' Month 4Health News:Search Underway for America's 'Ulti-mutt' Sports Pet 2Health News:Team treatment for depression cuts medical costs 2Health News:Team treatment for depression cuts medical costs 3
(Date:7/11/2014)... 2014 /PRNewswire-iReach/ -- VAPETEK™, Inc. has announced a ... use in portable vaporizers, which contains CBD, or ... cannabis, cannabidiol offers consumers a THC-free product made ... vaporizer technology. Photo - http://photos.prnewswire.com/prnh/20140711/126344 ... different compounds which are currently known, two of ...
(Date:7/11/2014)... According to a new ... Material, Application (Healthcare, Homeland security, Industrial application, Nuclear ... Hand-Held Instruments, Fixed, and Installed Instruments) & Geography ... by MarketsandMarkets, the Scintillator Market is expected to ... to 2020, and reach $479.16 Million in 2020. ...
(Date:7/11/2014)... ALBANY, New York , July 11, 2014 /PRNewswire/ ... published by Transparency Market Research "Endoscopy Devices Market (Endoscopes, ... Analysis, Size, Share, Growth, Trends and Forecast, 2013-2019" the ... billion in 2012 and is expected to grow at ... reach an estimated value of USD 36.9 billion in ...
Breaking Medicine Technology:VAPETEK Releases CBD-Infused eLiquid For The Consumer Market 2Scintillator Market will be worth $479.16 Million by 2020 2Scintillator Market will be worth $479.16 Million by 2020 3Scintillator Market will be worth $479.16 Million by 2020 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 5Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 6
... Merger Agreement with Tonsun International Company Limited,... -- SHENZHEN, China, Nov. 1, 2010 /PRNewswire-Asia-FirstCall/ -- ... ... if (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... var shortURL = ""; BitlyCB.alertResponse = function(data) { var s = ,; var first_result; ...
... NICOSIA, Cyprus, Nov. 1, 2010 MedWOW.com, the global online ... the addition of its newest user-oriented tool: a Medical ... difficult and costly process to look for replacement parts for ... to streamline the search for buyers unable to find the ...
Cached Medicine Technology:Tongjitang Chinese Medicines Enters into Merger Agreement with Tonsun International Company Limited, Hanmax Investment Limited and Fosun Industrial Co., Limited 2Tongjitang Chinese Medicines Enters into Merger Agreement with Tonsun International Company Limited, Hanmax Investment Limited and Fosun Industrial Co., Limited 3Tongjitang Chinese Medicines Enters into Merger Agreement with Tonsun International Company Limited, Hanmax Investment Limited and Fosun Industrial Co., Limited 4Tongjitang Chinese Medicines Enters into Merger Agreement with Tonsun International Company Limited, Hanmax Investment Limited and Fosun Industrial Co., Limited 5Tongjitang Chinese Medicines Enters into Merger Agreement with Tonsun International Company Limited, Hanmax Investment Limited and Fosun Industrial Co., Limited 6Tongjitang Chinese Medicines Enters into Merger Agreement with Tonsun International Company Limited, Hanmax Investment Limited and Fosun Industrial Co., Limited 7Tongjitang Chinese Medicines Enters into Merger Agreement with Tonsun International Company Limited, Hanmax Investment Limited and Fosun Industrial Co., Limited 8Tongjitang Chinese Medicines Enters into Merger Agreement with Tonsun International Company Limited, Hanmax Investment Limited and Fosun Industrial Co., Limited 9Tongjitang Chinese Medicines Enters into Merger Agreement with Tonsun International Company Limited, Hanmax Investment Limited and Fosun Industrial Co., Limited 10Tongjitang Chinese Medicines Enters into Merger Agreement with Tonsun International Company Limited, Hanmax Investment Limited and Fosun Industrial Co., Limited 11Tongjitang Chinese Medicines Enters into Merger Agreement with Tonsun International Company Limited, Hanmax Investment Limited and Fosun Industrial Co., Limited 12MedWOW Adds Parts Finder Service and Enhances Business Model 2
The PC4200i is the largest capacity platelet incubator available. It features a built-in agitator with a capacity of 396 random bags (132 apheresis)....
... rotators and agitators for continual ... set at 22C (71F) or ... (59F to 104F). Uniformity is ... bottom. Recorder is standard on ...
An enzyme-linked immuno-sorbent assay for the detection and quantitation of anti-tissue Transglutaminase in serum of patients with Celiac Disease and Dermatitis Herpetiformis....
Anti Gliadin IgG Enzyme Immunosay for quantitative determination of Gliadin-IgG antibodies in serum....
Medicine Products: