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Scientists test 5,000 combinations of 100 existing cancer drugs to find more effective treatments
Date:11/6/2012

mbinations, i.e. making scientific inferences about which pathways it might make sense to block simultaneously with different drugs. We took a step back, and took an approach that tests all possible drug pairs. This allowed us to test not only the rational combinations, but also to explore drug pairs that otherwise would likely never be tested together."

Professor Stefan Sleijfer, the scientific chair of the EORTC-NCI-AACR Symposium, from Erasmus University Medical Centre (The Netherlands), commented: "This study is interesting because of the use of combinations of drugs already approved and on the market, which were tested in cell lines that have been well characterised in terms of genetic profiles. If confirmed, this study will form a basis for future clinical trials on such combinations in well-defined patient groups."


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ECCO-the European CanCer Organisation
Source:Eurekalert

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