Navigation Links
Scientists step up hunt for bacterial genes tied to Lyme disease
Date:10/26/2012

Investigators at The University of Texas Health Science Center at Houston (UTHealth) have accelerated the search for the bacterial genes that make the Lyme disease bacterium so invasive and persistent. The discovery could advance the diagnosis and treatment of this disease, which affects an estimated 30,000 Americans each year.

The researchers have developed a new technique that allowed them to test 15 times more bacterial genes than had been evaluated in the previous 30 years to ascertain their roles in infection. Findings appeared Oct. 25 in the journal The Public Library of Science ONE (PLOS ONE), an international, peer-reviewed, open-access, online publication.

Scientists hope to use this information to unravel the mystery of how the spiral-shaped bacterium Borrelia burgdorferi causes Lyme disease. Ticks carry the bacterium and transfer it to animals and humans when the tiny spider-like creatures bite. The Lyme disease microorganism was discovered in 1981.

"We believe that this will be one of the most significant publications in Lyme disease in the next several years. This global approach will help 'move the field forward' and also serve as a model for other pathogens with similar properties," said Steven Norris, Ph.D., the study's senior author and the vice chair for research in the Department of Pathology and Laboratory Medicine at the UTHealth Medical School.

The bacterium can invade almost any tissue in humans or animals and trigger an infection that lasts from months to years. Its symptoms include a reddish rash that often resembles a bull's eye and flu-like symptoms. The disease can lead to nervous system problems, joint inflammation and heart abnormalities. Most instances of Lyme disease can be treated with antibiotics.

"Our long-term goals are to screen, identify and characterize the virulence determinants of the Lyme disease bacterium and thereby dissect the mechanism of pathogenesis in mammal
'/>"/>

Contact: Robert Cahill
Robert.Cahill@uth.tmc.edu
713-500-3030
University of Texas Health Science Center at Houston
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Scientists to study the role genes play in treating TB
2. Kessler Foundation scientists awarded New Jersey grants for brain injury research
3. Scientists Focus on Factors Behind Asthma Attacks
4. Einstein-Montefiore scientists awarded 2 NCI Provocative Questions grants
5. Leading stem cell scientists to focus on diabetes, eye diseases at Cedars-Sinai symposium
6. Diets High in Fructose May Harm Liver in Some, Scientists Warn
7. Cardiff scientists bid to develop anthrax vaccine to counteract world bioterrorism threat
8. Scripps Research Institute scientists show protein linked to hunger also implicated in alcoholism
9. Scientists Spot 5 Genes That Help Shape Faces
10. Eight scientists honored in first annual Golden Goose Awards
11. Scientists Map Genetic Blueprint of Heart
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists step up hunt for bacterial genes tied to Lyme disease
(Date:1/22/2015)... (PRWEB) January 22, 2015 Padre Murphy's and ... supporter of Pro Player Health Alliance (PPHA). The ... Murphy's in getting everyone, including NFL greats, treated for obstructive ... the leading groups supporting the cause in the valley. The ...
(Date:1/22/2015)... AngelWeddingDress, the premier women’s dress supplier, ... dresses. View website of AngelWeddingDress.com to find ... wedding dresses online for a bridal party. AngelWeddingDress offers ... for them. Its maternity wedding dresses are specially designed ...
(Date:1/22/2015)... Autocarinsurancebest.com has released a new blog post explaining the ... . , Auto insurance quotes help many drivers find ... necessary to call an agent or visit an agency for ... single website: http://autocarinsurancebest.com/ . , Every business who relies ...
(Date:1/22/2015)... 22, 2015 Yesterday, Senator Holly ... and Kristin Olsen (R-Modesto) were honored by the ... advancing biotechnology, biomedical science, medical device and pharmaceutical ... received the “2014 Life Sciences Champion” award from ...
(Date:1/22/2015)... 2015 EBSCO Information Services (EBSCO) ... their relationship in an effort to further promote visibility and ... EBSCO has long made AMA journals available via its subscription ... The JAMA Network. , Long known as both ...
Breaking Medicine News(10 mins):Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4
... , WEDNESDAY, May 30 (HealthDay News) -- Nearly one in four ... be triggered by hot summer weather. Hives are itchy, red ... can be acute or chronic, according to the American Academy of ... than a day or up to six weeks, are likely a ...
... Breast-cancer researchers at the University of Wisconsin-Madison have found that ... together as a team to maintain normal activity in mammary ... breast cell types. They may also drive the development and ... Journal of Biological Chemistry , the research also suggests ...
... , , , , , , ... AUDIO: Smoking researchers at Washington University School of Medicine in Sr. Louis have found that the same genetic variations that ... for more information. , , , , ... , , , , , , , ...
... that can rapidly screen cells for leukemia or HIV ... can produce three-dimensional focusing of a stream of cells, ... counting CD4 cells," said Tony Jun Huang, associate professor ... of the diagnoses are done using flow cytometry." ...
... in one side of their visual field benefit from ... hearing sounds for an hour, their visual detection of ... field improved significantly. Neural pathways that simultaneously process information ... have embarked on a whole new therapy approach" says ...
... TUESDAY, May 29 (HealthDay News) -- Women who develop fevers ... have a child with autism spectrum disorder or another developmental ... if, fevers may increase the risk for autism is unknown, ... if they do develop a fever while pregnant because taking ...
Cached Medicine News:Health News:Summer's Heat May Enflame Hives 2Health News:Breast stem-cell research: Receptor teamwork is required and a new pathway may be involved 2Health News:Breast stem-cell research: Receptor teamwork is required and a new pathway may be involved 3Health News:Genes predict if medication can help you quit smoking 2Health News:Genes predict if medication can help you quit smoking 3Health News:Genes predict if medication can help you quit smoking 4Health News:Biochip-based device for cell analysis 2Health News:Biochip-based device for cell analysis 3Health News:Hear to see: New method for the treatment of visual field defects 2Health News:Fever During Pregnancy May Raise Odds for Autism in Offspring 2Health News:Fever During Pregnancy May Raise Odds for Autism in Offspring 3
(Date:1/23/2015)... 2015 Gem Pharmaceuticals announced today that the initial ... the Company,s Phase 2 clinical trial.  This open-label study ... compound, GPX-150 (an investigational medication), in approximately 30 adults ... Logo - http://photos.prnewswire.com/prnh/20150123/170966LOGO ...
(Date:1/22/2015)... Jan. 22, 2015  Uroplasty, Inc. (NASDAQ: UPI ), ... innovative proprietary products to treat voiding dysfunctions, today reported ... 31, 2014.  Global revenue for the Company,s ... million, a new quarterly revenue record, as compared to ...
(Date:1/22/2015)... SAN DIEGO , Jan. 22, 2015  Profil Institute ... focused on diabetes and obesity, announced today a new ... Drug Development,  published by Springer, a leading global scientific ... extensively analyze and illustrate techniques for use in early ...
Breaking Medicine Technology:Gem Pharmaceuticals Announces Enrollment of Initial Patients in its Phase 2 Clinical Trial to Assess the Efficacy and Safety of GPX-150 in Sarcoma Patients 2Uroplasty Reports Record Revenue in Fiscal Third Quarter 2Uroplasty Reports Record Revenue in Fiscal Third Quarter 3Uroplasty Reports Record Revenue in Fiscal Third Quarter 4Uroplasty Reports Record Revenue in Fiscal Third Quarter 5Uroplasty Reports Record Revenue in Fiscal Third Quarter 6Uroplasty Reports Record Revenue in Fiscal Third Quarter 7Uroplasty Reports Record Revenue in Fiscal Third Quarter 8Uroplasty Reports Record Revenue in Fiscal Third Quarter 9Uroplasty Reports Record Revenue in Fiscal Third Quarter 10Uroplasty Reports Record Revenue in Fiscal Third Quarter 11Uroplasty Reports Record Revenue in Fiscal Third Quarter 12Uroplasty Reports Record Revenue in Fiscal Third Quarter 13Uroplasty Reports Record Revenue in Fiscal Third Quarter 14Uroplasty Reports Record Revenue in Fiscal Third Quarter 15Uroplasty Reports Record Revenue in Fiscal Third Quarter 16Uroplasty Reports Record Revenue in Fiscal Third Quarter 17Uroplasty Reports Record Revenue in Fiscal Third Quarter 18New Textbook "Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development" Provides Critical Review Of Current And Emerging Clinical Investigation Methods 2New Textbook "Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development" Provides Critical Review Of Current And Emerging Clinical Investigation Methods 3
... PARSIPPANY, N.J., July 7, 2011 Watson Pharmaceuticals, Inc. ... United States Court of Appeals for the Federal Circuit ... Southern District of Florida,s February 2011 decision that Watson,s ... Mucinex(R) DM (Dextromethorphan HBr/ Guaifenesin) Extended-Release products do not ...
... 2011 Watson Pharmaceuticals, Inc. (NYSE: ... Laboratories, Inc., filed an Abbreviated New Drug Application ... (FDA) seeking approval to market lisdexamfetamine dimesylate capsules. ... of Shire LLC,s Vyvanse®. Vyvanse® is a prescription ...
Cached Medicine Technology:Watson Confirms Favorable Appeals Court Decision in Mucinex(R) Patent Suit 2Watson Confirms Vyvanse® Patent Challenge 2
... 14A and 14C have been approved. The three ... the variations in the size of the individual ... are designed to stabilize the capsule and have ... of U.S. ophthalmologists. For implatations of the ...
... is a device designed for permanent implantation ... removal surgery. It provides secondary capsular bag ... The CTR is a uniplanar, 270-degree, semi-circle ... absorbing polymethylmethacrylate (PMMA) with one manipulation eyelet ...
Stainless steel cartilage scissors....
Hannum rongeur/grasper with teth in jaws and non-locking design....
Medicine Products: