Navigation Links
Scientists shed new light on link between 'killer cells' and diabetes
Date:1/15/2012

Killer T-cells in the human body which help protect us from disease can inadvertently destroy cells that produce insulin, new research has uncovered.

The study provides the first evidence of this mechanism in action and could offer new understanding of the cause of Type 1 diabetes.

Professor Andy Sewell, an expert in human T-cells from Cardiff University's School of Medicine worked alongside diabetes experts from King's College London to better understand the role of T-cells in the development of Type 1 diabetes.

The team isolated a T-cell from a patient with Type 1 diabetes to view a unique molecular interaction which results in the killing of insulin-producing cells in the pancreas.

"Type 1 diabetes is a result of the body's own immune system attacking and destroying the cells in the pancreas that manufacture the hormone insulin. Insulin controls blood sugar levels and a lack of insulin is fatal if untreated," said Professor Sewell.

"The mechanism by which the body attacks its own insulin producing cells in the pancreas is not fully understood. Our findings show how killer T-cells might play an important role in autoimmune diseases like diabetes and we've secured the first ever glimpse of the mechanism by which killer T-cells can attack our own body cells to cause disease," he added.

Co-author of the study, Professor Mark Peakman from the National Institute for Health Research (NIHR) Biomedical Research Centre at King's College London and Guy's and St Thomas' NHS Foundation Trust said: "This first sight of how killer T-cells make contact with the cells that make insulin is very enlightening, and increases our understanding of how Type 1 diabetes may arise.

"This knowledge will be used in the future to help us predict who might get the disease and also to develop new approaches to prevent it. Our aim is to catch the disease early before too many insulin-producing cells have been damaged."'/>"/>

Contact: Andy Sewell
sewellak@cardiff.ac.uk
44-292-068-7007
Cardiff University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Scientists Pinpoint Area of Brain That Fears Losing Money
2. Scientists Discover How HIV Is Transmitted Between Men
3. Prevention Is Key Research Goal for Premature Babies, Scientists Say
4. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
5. Scientists find donut-shaped structure of enzyme involved in energy metabolism
6. Neuroscientists reveal new links that regulate brain electrical activity
7. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. Scientists Spot Genetic Fingerprints of Individual Cancers
10. Scientists Unravel Mysteries of Intelligence
11. MSU scientists develop more effective method of predicting lead-poisoning risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... Pennsylvania (PRWEB) , ... July ... ... largest e-commerce janitorial supply company , announced today that it has ... Products. The acquisition will make CleanItSupply.com the largest distributor of Rubbermaid Commercial ...
(Date:7/2/2015)... ... July 02, 2015 , ... Breakthrough technologies ... pain treatment. Dr. Lev Kalika, founder of New York Dynamic Neuromuscular Rehabilitation ... on the conservative treatment of back, hip, knee and shoulder pain as well ...
(Date:7/2/2015)... ... July 02, 2015 , ... Five ... Preparedness (CDP) in Anniston for specialized disaster training. The team – composed of ... the Southern California Hospital Association who attended the training, which is dedicated to ...
(Date:7/2/2015)... ... July 02, 2015 , ... B. E. ... been retained to lead a national chief executive officer recruitment for ... in the healthcare industry, B. E. Smith has recently placed more than 1,000 ...
(Date:7/2/2015)... AR (PRWEB) , ... July 02, 2015 , ... Throughout ... families through their annual “Dog Tag” campaign. On Tuesday, July 7, Casey’s General ... Warriors® for nearly $800,000. Hope For The Warriors® is a national nonprofit dedicated to ...
Breaking Medicine News(10 mins):Health News:CleanItSupply.com Acquires eRubbermaid.com 2Health News:Breakthrough Technologies for Carpal Tunnel Treatment in New York City 2Health News:Breakthrough Technologies for Carpal Tunnel Treatment in New York City 3Health News:Breakthrough Technologies for Carpal Tunnel Treatment in New York City 4Health News:Team from Loma Linda University Health Receives Specialized Disaster Training at FEMA’s Center for Domestic Preparedness 2Health News:Team from Loma Linda University Health Receives Specialized Disaster Training at FEMA’s Center for Domestic Preparedness 3Health News:Indiana Blood Center Retains B. E. Smith to Recruit New Chief Executive Officer 2Health News:Indiana Blood Center Retains B. E. Smith to Recruit New Chief Executive Officer 3Health News:Casey’s General Stores to Present Donation from “Dog Tag” Campaign to Hope For The Warriors® 2Health News:Casey’s General Stores to Present Donation from “Dog Tag” Campaign to Hope For The Warriors® 3
... of effectiveness over time , , MONDAY, May 12 (HealthDay News) ... legs syndrome do provide relief, but they are burdened by ... many sufferers to stop taking them, a new analysis finds. ... can,t fully explain is that they have more robust effects ...
... baby boomers say,they are financially unprepared for a ... Harris Interactive on behalf of America,s Health,Insurance Plans ... and,many would have to tap into their retirement ... ), "Baby boomers have too much ...
... assessments worldwide verify safety and quality of technically ... advanced zirconium oxide material., ... provider of,ceramic solutions for the medical device industry, has submitted ... (FDA) for,its new technical ceramic dental component, ZirDent(TM) CAD/CAM Blocks.,ZirDent(TM) ...
... CHENGDU, China, May 12 /Xinhua-PRNewswire-FirstCall/ -- Tianyin,Pharmaceutical, Co., ... of modernized traditional Chinese medicine ("TCM") based in,Chengdu, ... at Roth Third,Annual China Discovery Tour on Tuesday, ... Conference will be held at the Regent Hotel ...
... trial in bladder cancer exceeds 2/3rds enrolment level ... pre-clinical work in peritoneal cancers -, BELLEVILLE, ... (TSX: BNC), a research-based, technology-driven Canadian,biopharmaceutical company, is ... non-clinical development of its proprietary platform technology:,Mycobacterial Cell ...
... Re-implantation of devices at shorter distances improved motor scores, ... A few millimeters can make a huge difference for ... brain, a new study finds. , Implanting electrodes ... brain potentially related to impulsivity, has helped people with ...
Cached Medicine News:Health News:Drugs for Restless Legs Syndrome Have Downsides 2Health News:Drugs for Restless Legs Syndrome Have Downsides 3Health News:Most Baby Boomers are Financially Unprepared for a Potential Disability 2Health News:C5 Medical Werks Applies for Clearance, Certification and Licensing for the Global Marketing of ZirDent(TM) Ceramic CAD/CAM Dental Blocks 2Health News:Tianyin Pharmaceutical to Present at Roth Third Annual China Discovery Tour in Beijing on May 20, 2008 at 12:40 p.m. Beijing Time 2Health News:Bioniche Updates re: Mycobacterial Cell Wall Technology Platform 2Health News:Bioniche Updates re: Mycobacterial Cell Wall Technology Platform 3Health News:Bioniche Updates re: Mycobacterial Cell Wall Technology Platform 4Health News:Electrode Placement Key to Brain Stimulation for Parkinson's Patients 2
(Date:7/2/2015)... , June 25, 2015 ... of the "Veterinary / Animal Vaccines Market by ... report to their offering. The global ... by 2020 from $5,507.3 Million in 2015, at a ... Major factors fueling market growth are growing prevalence of ...
(Date:7/2/2015)... Agreement reinforces ...   ViiV Healthcare and Desano Pharmaceuticals (Desano) ... China of dolutegravir. The agreement will ... (API), and will allow ViiV Healthcare to offer a competitive ... name Tivicay®) for China and a ...
(Date:7/1/2015)... Colo. , July 1, 2015   ... in implantable hearing solutions, announced today the US ... Cochlear™ Nucleus® Profile™ Implant with Slim Straight Electrode ... and developed in close collaboration with the world,s ... cochlear implant platform designed to provide the most ...
Breaking Medicine Technology:Veterinary / Animal Vaccines Market 2015 - Global Forecast to 2020 for the $7.19 Billion Industry 2ViiV Healthcare and Desano Pharmaceuticals' Manufacturing Agreement Will Allow Competitive Supply of Dolutegravir in China and Several Developing Countries 2ViiV Healthcare and Desano Pharmaceuticals' Manufacturing Agreement Will Allow Competitive Supply of Dolutegravir in China and Several Developing Countries 3ViiV Healthcare and Desano Pharmaceuticals' Manufacturing Agreement Will Allow Competitive Supply of Dolutegravir in China and Several Developing Countries 4ViiV Healthcare and Desano Pharmaceuticals' Manufacturing Agreement Will Allow Competitive Supply of Dolutegravir in China and Several Developing Countries 5ViiV Healthcare and Desano Pharmaceuticals' Manufacturing Agreement Will Allow Competitive Supply of Dolutegravir in China and Several Developing Countries 6Cochlear Combines the World's Thinnest Cochlear Implant Platform with the Industry's Thinnest Full Length Electrode 2Cochlear Combines the World's Thinnest Cochlear Implant Platform with the Industry's Thinnest Full Length Electrode 3
... Inc. (Nasdaq: MYL ) today announced that its ... Food and Drug Administration (FDA) for its Abbreviated New Drug ... and 500 mg Single-use Vials. This product is the generic ... a chemoprotective agent. Dexrazoxane for Injection, when indicated ...
... Nov. 28, 2011 Gaylord Sleep Medicine now offers ... Glastonbury, Guilford, North Haven and Trumbull locations. ... Sleep Apnea Management program has expanded to offer PAP ... needs. Originally designed to improve PAP compliance, the program ...
Cached Medicine Technology:Gaylord Sleep Medicine Expands Sleep Apnea Management Program 2
Used for access and catheterization procedures. Double flexible tipped design permits alternative use of both ends of wire guide depending upon procedural needs. Supplied sterile in peel-open package...
Used for complex diagnostic and interventional procedures....
The Emerald Guidewire is intended for percutaneous introduction of catheters....
... Medical offers a complete line ... with percutaneous catheter introducers to ... catheters. Our diagnostic guidewires are ... incorporate a proprietary surface finish ...
Medicine Products: