Navigation Links
Scientists scan the human heart to create digital anatomical library
Date:4/18/2013

On April 18th JoVE (Journal of Visualized Experiments) will publish a new video article by Dr. Paul A Iaizzo demonstrating the anatomical reconstruction of an active human heart. The research uses contrast-computed tomography (CT) to allow in-depth 3-D computer modeling of hearts that can be used for prolonged archiving.

Computational technology, when combined with advanced imaging techniques like CT, gives researchers extensive insight to the structure and function of human organs. While often these techniques may be applied to modeling structural elements like a vertebrate's skeletal system, applying these imaging capabilities to cardiac tissue can create maps of an individual heart's venous system and musculature. In JoVE's new video article, surgeons and biomedical engineers from the University of Minnesota use these new technologies to create a digital library of human heart specimens.

Dr. Iaizzo's laboratory is able to collect human heart specimens from organ donors that were not deemed viable for transplant because the donor had been expired for too long, had a congenital heart defect, or the donor organ did not match a patient's immediate need. In these cases, Dr. Iaizzo and his colleagues around the world gain access to these organs for medical research and indexing. "We can look at a lot of the variations in heart anatomy [and] because everybody's heart is unique we can really understand variations and how the heart changes with disease."

By using contrast dyes and other reagents, Dr. Iaizzo can preserve and prepare the donated hearts to be in a diastolic state, the part of a heartbeat where the heart is filled with blood from the ventricles before expelling it into the aortas. This brings a deeper insight into physiological attributes of the heart, including fluid capacity and pressure on the heart chambers. Once the preserved hearts are scanned, computer models are generated, which allow approximations and correlations to be established between various heart shapes and disorders. Dr. Iaizzo expects this to assist in the design of cardiac devices.

"You don't have an appreciation for these specimens, and that you can still add contrast agents to them, without the video component," Dr. Iaizzo says of his decision to publish his methods in a video article, "The JoVE video shows how you can critically develop these [3-D models]. If someone is developing devices that can go into a cardiac venous or arterial system, then you can really look at these before and after treatments and see how the therapy actually worked."


'/>"/>

Contact: Rachel Greene
press@jove.com
617-250-8451
The Journal of Visualized Experiments
Source:Eurekalert

Related medicine news :

1. Scientists Create Breast Cancer Survival Predictor
2. Molecule treats leukemia by preventing cancer cell repair, Jackson Laboratory scientists report
3. Scientists map elusive 3-D structure of telomerase enzyme, key actor in cancer, aging
4. Scientists discover gene mutation that causes children to be born without spleen
5. Unusual suspect: Hopkins scientists find second fiddle proteins role in Type 2 diabetes
6. Polio eradication is achievable by 2018 and urgent, declare 400+ global scientists
7. Scientists create phantom sensations in non-amputees
8. Scientists Map Genome for Dutch Elm Disease Fungus
9. Could Scientists Peek Into Your Dreams?
10. CWRU-led scientists build material that mimics squid beak
11. Singapore clinician-scientists identify new type of deadly lymphoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/23/2017)... PHILADELPHIA (PRWEB) , ... February 23, 2017 , ... ... risk and uncertainty in clinical trials, today announced that Premier Research, a leading ... management solution. , Clinical trials are becoming increasingly complex, due in part to ...
(Date:2/23/2017)... RI (PRWEB) , ... February 23, 2017 , ... ... today a new partnership with the Rhode Island Consortium for Autism Research and ... an opportunity for children with autism spectrum disorder (ASD) to see films in ...
(Date:2/23/2017)... ... 2017 , ... Top cosmetic and periodontal dentist Dr. Mahnaz Rashti ... Indiegogo campaign . Individuals are now able to contribute to the local initiative, ... as a participating patient or through an Indiegogo donation. The entirety of proceeds will ...
(Date:2/23/2017)... ... ... Thomas Vas-Don suffered from severe injury due to an industrial ... recover. In “ Origin & Insertion Charts for Massage Therapists ” (published by Xlibris ... anatomy , trigger points and referral pain patterns . , In this ...
(Date:2/22/2017)... NY (PRWEB) , ... February 22, 2017 , ... ... life and athletics. It’s enough to overwork even the sharpest brain. , Power ... offer peak healthy activity without over clocking the brain. Each capsule contains Cognizin® ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... Ga., Feb. 23, 2017  MiMedx Group, Inc. (NASDAQ: ... tissue and patent-protected processes to develop and market advanced ... Spine, Sports Medicine, Ophthalmic, and Dental sectors of healthcare, ... and full year ended December 31, 2016. ... Revenue is a 31% increase over full year 2015 ...
(Date:2/23/2017)... , Feb. 23, 2017 LG Innotek today announced that ... sterilization applications. As its sterilization performance is 1.5 times higher than ... wavelength ultraviolet rays in the range of 200 -- 280nm, allowing it ... bacteria by destroying their DNA. LG Innotek,s product emits UV in ... ...
(Date:2/23/2017)... , Feb 23, 2017 Research and ... Devices Market Analysis & Trends - Industry Forecast to 2025" ... ... grow at a CAGR of around 9.2% over the next decade ... report analyzes the market estimates and forecasts for all the given ...
Breaking Medicine Technology: