Navigation Links
Scientists pinpoint gene linked to drug resistance in malaria
Date:10/13/2010

Scientists have shed light on how malaria is able to resist treatment with a leading drug.

Researchers have identified a gene that enables the parasite that causes the infection to resist treatment with the plant-based remedy artemisinin.

In many countries where the parasite has developed resistance to previously effective common treatments such as chloroquine, artemisinin remains the only effective treatment against the infection. However, malarial resistance to artemisinin appears to be developing, potentially creating problems in controlling malaria.

Identification of this gene paves the way for further studies that could eventually help control the development of resistance to artemisinin and lead to more effective drugs for human malaria.

The study, by scientists from the University of Edinburgh and the Universidade Nova de Lisboa, used emerging technology to scan the genetic fingerprint of drug resistant parasites that infect rodents. This technology allows rapid identification of genes that enable the parasite to withstand existing drug treatments.

There are estimated to be between 300 and 500 million cases of malaria each year, occurring in over 90 different countries, according to the World Health Organisation.

Dr Paul Hunt, from the University of Edinburgh's School of Biological Sciences, said: "This knowledge from rodent malaria parasites opens up new directions that will allow this gene to be investigated in human malaria. This may help track the evolution of drug resistance and may eventually enable the design of alternative, effective drugs."


'/>"/>

Contact: Catriona Kelly
catriona.kelly@ed.ac.uk
44-131-651-4401
University of Edinburgh
Source:Eurekalert

Page: 1

Related medicine news :

1. Scientists Pinpoint Area of Brain That Fears Losing Money
2. Scientists Discover How HIV Is Transmitted Between Men
3. Prevention Is Key Research Goal for Premature Babies, Scientists Say
4. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
5. Scientists find donut-shaped structure of enzyme involved in energy metabolism
6. Neuroscientists reveal new links that regulate brain electrical activity
7. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. Scientists Spot Genetic Fingerprints of Individual Cancers
10. Scientists Unravel Mysteries of Intelligence
11. MSU scientists develop more effective method of predicting lead-poisoning risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/19/2017)... ... February 19, 2017 , ... ... healthcare, will join forces with Healthwise ® at HIMSS 2017 ... industry leader in evidence-based health education, technology and services, will demonstrate a voice-powered ...
(Date:2/18/2017)... ... 17, 2017 , ... CONTACT:, Glenn Vallecillos, MD, FACS, +1 ... Dr. Glenn Vallecillos experiments SculpSure, the hot, new, aesthetic, non-surgical procedure ... been centered around that idea that to achieve ones desired results a surgical ...
(Date:2/17/2017)... ... February 17, 2017 , ... Smiles by Seese is ... in Davidson, NC. Dr. Brian Seese leads the practice as a skilled and highly ... one roof. Smiles by Seese serves patients of all ages with excellence in general, ...
(Date:2/17/2017)... ... 2017 , ... For the first time, International Scholarship and ... floor for the 2017 HIMSS Conference & Exhibition at the Orange ... than 40,000 healthcare industry professionals are expected at the conference, where they will ...
(Date:2/17/2017)... ... February 17, 2017 , ... ... named a finalist in the 8th Annual DecisionHealth Platinum Awards in recognition of ... Qualis Health’s work is recognized across multiple award categories, highlighting four of the ...
Breaking Medicine News(10 mins):
(Date:2/16/2017)... -- Summary Provides understanding and access to the ... healthcare companies. ... The Global Allergy Partnering Terms and Agreements since 2010 report ... by the world,s leading healthcare companies. - Trends ... Deals listed by company A-Z, industry sector, stage of development, technology ...
(Date:2/16/2017)... and SCOTTSDALE, Ariz. , Feb. 16, ... Health Information Exchange (HIE), announced today it is partnering with ... HealthInfoNet,s HIE contains 98% of all Maine ... Maine hospitals and over 500 ambulatory care ... Directors, HealthInfoNet plans to deploy Orion Health,s Amadeus , ...
(Date:2/16/2017)... 2017   Spectralink Corporation , the global ... retail, manufacturing and hospitality industries, today announced the ... symbology support features of its PIVOT™:SC (8744) ... The study, conducted by The Tolly Group, showed ... phones with dedicated hardware scanners. Spectralink ...
Breaking Medicine Technology: