Navigation Links
Scientists identify new strategy to fight deadly infection in cystic fibrosis
Date:1/23/2013

mer said.

Abdulrahman observed that in cells with the CF mutation, a key molecule gets caught up in those clumps. This molecule, beclin1, has a critical autophagy job, essentially escorting foreign particles to the cell parts that digest them and clear them away.

"Our hypothesis was that if we downregulate p62, this will release beclin1 from the aggregates. Once it's available, we will have active autophagic machinery that is able to control the infection," said Abdulrahman, first author on the paper.

In contrast, lowering p62 in macrophages from normal mice allowed the B. cenocepacia bacteria to grow. This confirmed that p62 actually controls the infection in cells from healthy animals but has the opposite effect when the CF mutation is present, she said.


'/>"/>
Contact: Amal Amer
amal.amer@osumc.edu
614-247-1566
Ohio State University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Social Scientists call for more effective teaching in Higher Education
2. UT MD Anderson scientists find protein that reins in runaway network
3. Study Finds Older Male Scientists Likelier to Commit Research Fraud
4. NIH scientists identify protective role for antibodies in Ebola vaccine study
5. Johns Hopkins neuroscientists win National Academy of Science Awards
6. Scientists find a new way to boost common cancer drugs
7. Cancer scientists determine mechanism of 1 of the most powerful tumor-suppressor proteins, Chd5
8. New American Chemical Society video series: Conversations with Celebrated Scientists
9. Scientists discover how deadly skin cancer spreads into other parts of the body
10. Scientists ID New Genetic Connection for Gout
11. Scientists Shed Light on Fungus Behind Deadly Pneumonia Strain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... (PRWEB) July 30, 2014 Recent ... medical devices have determined Nurse Call Systems to ... legislation, this requires all Nurse Call Systems to ... practice improves patient safety, reduces clinical risks, and ... hospital based Corporate Risk and Clinical Risk Committee ...
(Date:7/29/2014)... Daily Gossip reveals in its review that the Tinnitus Miracle ... eliminate all the symptoms associated to this condition. , ... such as mild hearing loss, as well as headaches. The ... gone forever. , The method will lead to a cure ... says that at the end of the treatment, sufferers will ...
(Date:7/29/2014)... Denver, CO (PRWEB) July 29, 2014 Daily ... method reveals some unique tips to gain beautiful and clear ... some cases, sufferers will see these positive results even sooner ... acne sufferer, Mike Walden, who used this step by step ... suffered from severe acne for years. Mike battled this condition ...
(Date:7/29/2014)... For survivors of severe combat injuries threatening more ... have a good record of safety and effectiveness in ... of Plastic and Reconstructive Surgery , ... of Plastic Surgeons (ASPS). , Experience with multiple ... Afghanistan shows good success rates, with no increase in ...
(Date:7/29/2014)... TUESDAY, July 29, 2014 (HealthDay News) -- Chlorine helps ... swimmers more likely to develop eye infections, doctors say. ... eyes as well as blurry vision, said Dr. Sampson ... Center in New Jersey. It,s important to understand ... pools washes away the outer film layer of the ...
Breaking Medicine News(10 mins):Health News:NiQ Health Reveals the Extensive Use of Unregulated Medical Devices in Australian Hospitals 2Health News:NiQ Health Reveals the Extensive Use of Unregulated Medical Devices in Australian Hospitals 3Health News:NiQ Health Reveals the Extensive Use of Unregulated Medical Devices in Australian Hospitals 4Health News:Tinnitus Miracle Review Exposes the Only Holistic System for Tinnitus Cure 2Health News:Acne No More Review Reveals Most Effective Acne Cure Program 2Health News:Good outcomes with multiple limb salvage after severe combat injuries, reports Plastic and Reconstructive Surgery 2Health News:Protect Your Eyes When Hitting the Pool 2
... in endurance sports, study finds , THURSDAY, June ... to strengthen inhalation muscles and reduce their need ... such as cycling and swimming, a new study ... muscle training (IMT) significantly reduced the amount of ...
... ... Between Sharks and Surfers. , ... (PRWEB) June 3, 2010 -- Surfline thinks it takes more than a week to explain ... in the presence and environment of sharks as surfers. Therefore, Surfline has launched "Shark Month" ...
... what it would be like to go on a mission ... will enter an isolation chamber in Moscow for a simulated ... the Russian Federation Institute for Biomedical Problems (IBMP) of ... schedule full of more than 90 experiments and realistic scenarios, ...
... Study ... ... -- Chemotherapy-induced amenorrhea in premenopausal women being treated for early stage breast cancer was ... the New England Journal of Medicine by the National Surgical Adjuvant Breast and Bowel ...
... Le Cordon ... worldwide “Apéritif à la Française" on June 3rd, 2010 at the Espace Réunion in Montreal, ... ... Ottawa Culinary Arts Institute is proud to announce that it will be one of the ...
... ... for Medical Marijuana Hydroponics Nutrients , ... Seattle, WA (PRWEB) June 3, 2010 -- In a landmark decision, ... hydroponics nutrients., , ,Oregon and most other states have regulatory agencies that ...
Cached Medicine News:Health News:Surfline Launches "Shark Month" Presented by Casio G'zOne 2Health News:520-day Mars mission simulation 2Health News:520-day Mars mission simulation 3Health News:520-day Mars mission simulation 4Health News:Interruption of Menstrual Cycle by Chemotherapy Associated with Improved Survival in Early Breast Cancer 2Health News:Interruption of Menstrual Cycle by Chemotherapy Associated with Improved Survival in Early Breast Cancer 3Health News:Interruption of Menstrual Cycle by Chemotherapy Associated with Improved Survival in Early Breast Cancer 4Health News:Le Cordon Bleu Ottawa to Sponsor Apritif la Franaise in Partnership with Sopexa 2Health News:Hydroponics Nutrients For Medical Marijuana Gain Government Approval 2
(Date:7/29/2014)...  Instrumentation Laboratory (IL) today announced the launch of its ... is part of a comprehensive rebranding effort by Werfen, the ... Boston, MA , in 1959, IL has been part ... companies in the group include Inova Diagnostics ( San ... Spain ).  Like IL, these three companies are focused ...
(Date:7/29/2014)... Research and Markets has announced the addition ... report to their offering. ... medical device used to provide medication or assist a ... achieve adequate oxygen levels to maintain life. Patients with ... ARDS require the need of respiratory devices. The medication ...
(Date:7/29/2014)... , July 29, 2014  Based on its ... (PERS) market, Frost & Sullivan recognizes MobileHelp with ... for Price Performance Value Leadership. MobileHelp,s leadership in ... expectations for tech progression in personal emergency response, ... these solutions. MobileHelp is at the ...
Breaking Medicine Technology:Instrumentation Laboratory Unveils New Corporate Brand 2Instrumentation Laboratory Unveils New Corporate Brand 3Global Respiratory Devices Market 2014-2018 2Frost & Sullivan Applauds MobileHelp for its Targeted Supplies for the PERS Market 2Frost & Sullivan Applauds MobileHelp for its Targeted Supplies for the PERS Market 3
... Horizon Pharma, Inc. announced today that it has filed a registration statement ... a proposed initial public offering of shares of its common stock.  All shares ... by the Company. , , , ... & Company, Inc. and Piper Jaffray & Co. are acting as ...
... Pharmaceuticals (NYSE: WPI ) today announced that ... as Senior Vice President, Global Operations, has been promoted to Executive Vice ... Bisaro , President and Chief Executive Officer of Watson. , ... Mr. Stewart will assume responsibility ...
Cached Medicine Technology:Horizon Pharma, Inc. Files Registration Statement for Proposed Initial Public Offering 2Watson Promotes Robert Stewart to Executive Vice President, Global Operations 2Watson Promotes Robert Stewart to Executive Vice President, Global Operations 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: