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Scientists identify genes that may signal long life in naked mole-rats
Date:11/3/2011

live underground with limited oxygen supply.

"It has been of interest to scientists for some time and we hope that by studying its genome it will help us understand the mechanisms of ageing and how the body protects itself from disease.

"These findings add further evidence to research that suggests genes responsible for mitochondria and oxireduction are associated with the ageing processes. It also provides some clues as to how naked mole-rats protect themselves against high levels of oxidative stress. The high levels of genes connected to energy production and cell decision-making systems may help in creating an intracellular environment that prevents cancer and other age-related diseases.

"This work provides candidate genes for specifying resistance to ageing and cancer that we can build on in future studies. The next stage of the research will be to observe what happens to the cells if gene levels change from high to low and vice-versa."

The research is published in the journal, PLoS ONE.


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Contact: Samantha Martin
samantha.martin@liv.ac.uk
44-151-794-2248
University of Liverpool
Source:Eurekalert

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