Navigation Links
Scientists identify gene that is consistently altered in obese individuals
Date:3/21/2013

r offspring. He believes that a lot of methylation starts in the womb and there are unfortunate real-life circumstances that support that theory.

For example, in the Dutch famine of 1944 near the end of World War II, babies born to starving mothers experienced DNA methylation that made them better able to survive such depravation, but in the more plentiful environment in which they grew up, put them at increased risk for cardiovascular disease as well as diabetes, obesity and other health problems.

He's already moving forward with more human studies as well, looking at a new group of lean and obese individuals, analyzing their DNA expression to see if increased methylation of LY86 means the gene is expressed more or less. Generally, higher methylation is thought to translate to lower gene expression.

He also wants to pin down whether methylation results from things like a high-fat diet, unfortunate genetics or both. These types of details may help explain why some individuals grow obese with a bad diet and little physical activity while others don't, Su said. It also may mean that positive environmental change, such as a better diet or more physical activity, can reverse at least some of the methylation. People may not get thin, for example, but they may reduce their risk for obesity-related disease, Su said.

LY86's clear importance in obesity emerged by first merging the gene list from the genome wide association studies with a genome wide methylation database on a small cohort of seven obese and seven lean individuals. The finding of increased methylation held up in subsequent groups of 46 obese/46 leans, 230 obese/413 leans as well as the general population panel of 703 at the GRU Institute of Public and Preventive Health. The research was supported by the National Institutes of Health.


'/>"/>

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Most men with erectile dysfunction remain untreated, say US scientists
2. Scientists investigate potential markers for a response to sunitinib in patients with metastatic RCC
3. Scientists ID Antibody That Might Boost Cancer Therapy
4. Scientists Report Clues to Flu Shots Effectiveness
5. Scientists discuss relationship between abortion and violence against women
6. A*STAR scientists discover switch critical to wound healing
7. Scientists uncover source of ovarian stem-like cells prone to give rise to ovarian cancer
8. Defective virus surprisingly plays major role in spread of disease, UCLA life scientists report
9. OHSU scientists first to grow liver stem cells in culture, demonstrate therapeutic benefit
10. Scientists Pinpoint How Deep Brain Stimulation Eases OCD
11. Scientists make older adults less forgetful in memory tests
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists identify gene that is consistently altered in obese individuals
(Date:6/3/2015)... Raleigh, NC (PRWEB) June 03, 2015 ... on two biomarkers for mesothelioma and say the tried-and-true ... has just posted an article on the research. ... in the University’s National Center for Asbestos Related Diseases ... false positive results, it is still preferable to fibulin-3 ...
(Date:6/3/2015)... June 03, 2015 Sitting at a ... discomfort in the back, neck, shoulders and/or wrists. This ... injuries. In addition, recent research links sitting for long ... chronic diseases. Fortunately, three inventors from Oakville, Ontario, are ... a desk. , They have developed a prototype for ...
(Date:6/3/2015)... On Sunday, June 7, 2015, tens of ... their local communities to observe the 28th annual National ... and abroad will hold celebrations on this day to ... challenges of cancer survivorship, and to show the world ... rewarding, and inspiring.,  , National Cancer Survivors Day® is ...
(Date:6/3/2015)... (PRWEB) June 03, 2015 Fourroux Prosthetics, ... Duluth, GA will celebrate its grand opening with a ... The first prosthetic center of its kind in the ... family unmatched care and outcomes through use of patented ... CPO & CEO of Fourroux Prosthetics, states, “Our goal ...
(Date:6/3/2015)... (PRWEB) June 03, 2015 These are ... sectors. The ever growing number of digital-first business are ... There is now a serious need for traditional businesses ... way they operate and deliver their services. On ... partnerships between incumbents and technology start-ups, to bring new ...
Breaking Medicine News(10 mins):Health News:Analysis Reveals Gold Standard Mesothelioma Biomarker Still the Best, According to Surviving Mesothelioma 2Health News:Adjustable Height Tabletop Unit Invented by Three InventHelp® Clients (TOR-9278) 2Health News:Communities to Recognize Cancer Survivors, Raise Awareness on National Cancer Survivors Day® – Sunday, June 7 2Health News:Communities to Recognize Cancer Survivors, Raise Awareness on National Cancer Survivors Day® – Sunday, June 7 3Health News:Communities to Recognize Cancer Survivors, Raise Awareness on National Cancer Survivors Day® – Sunday, June 7 4Health News:Fourroux Prosthetics Atlanta to Have Grand Opening Gala & Ribbon Cutting Ceremony 2Health News:Chief Digital Officer of Travelex joins Bayer, Abellio and Just Eat at The Open Mobile Summit London 2
... The Cardinal Health Foundation today announced that it ... a $100,000 grant to create education and outreach programs ... medication abuse and misuse in their communities. , According ... quarter of all Ohio high school students have reported ...
... LONDON, October 28 Even though no-one wants to admit it,the countdown ... at the,ubiquitous Christmas Party then follow the realbuzz.com guide to a healthier,you. ... living go out,the window, so now,s the time to turn your body ... be realbuzz.com if we didn,t offer this piece of,advice to start with! ...
... ... keys to exceptional marketing performance at your fingertips with his new web seminar hosted ... them will help pharmaceutical marketers understand what they can do to improve the effectiveness ... ...
... Ill., Oct. 28 Understanding the needs of patients ... providers, including enhancing safety and helping to stem the ... fact, many academic medical centers are turning to implementation ... quality of care for patients. , The Institute ...
... Oct. 27 Dr. Michael Feiz , lead surgeon at ... Lap Band surgeries than any other doctor. For ... is the answer they have been looking for to shed the ... with almost no scarring, Lap Band surgery has the ...
... Oct. 27 The St. Louis Cardinals, new hire of ... coach sends a message to all baseball and young people ... ," former White House drug policy spokesman Bob Weiner said ... the drugs? When McGwire used Andro (Androstenedione), now banned, he ...
Cached Medicine News:Health News:Cardinal Health Foundation, The Ohio State University College of Pharmacy Join Forces to Prevent Prescription Medication Abuse 2Health News:The Countdown to Christmas - The realbuzz.com Guide to a Healthier You! 2Health News:5 Steps to Pharmaceutical Marketing Happiness 2Health News:UHC Benchmarking Project Focuses on Patient- and Family-Centered Care in Academic Medical Centers 2Health News:UHC Benchmarking Project Focuses on Patient- and Family-Centered Care in Academic Medical Centers 3Health News:Beverly Hills Doctor (drfeiz.com) Performs the World's Most Lap Band Surgeries 2Health News:Mark McGwire's Message: Cheat, Do Drugs, Cover Up When Congress Investigates, Says Ex-White House Drug Spokesman Bob Weiner; World Series Should Test Both Teams During Games 2
(Date:6/3/2015)... Research and Markets  ( http://www.researchandmarkets.com/research/rf4hfn/global ) ... Neurodegenerative Diseases Market 2015-2019" report to their ... to grow at a CAGR of 4.77% over ... the present scenario and the growth prospects of ... 2015-2019. To calculate the market size, the report ...
(Date:6/3/2015)... June 3, 2015  EIP Pharma LLC ( www.eippharma.com ... clinical development of VX-745 in Alzheimer,s disease (AD) is ... and potent inhibitor of the alpha isoform of the ... alpha). "Recent human genetic data demonstrate that ... with symptomatic Alzheimer,s, while the science also indicates the ...
(Date:6/3/2015)... , June 02, 2015 Research and ... the "Europe Ultrasound Devices Market - Growth, Trends ... offering. Currently, the European market is dominated ... of France and ... increasing incidences of chronic diseases in these regions. ...
Breaking Medicine Technology:Global Neurodegenerative Diseases Market 2015-2019 - Reformulation of Marketed Drugs 2EIP Pharma announces first patient dosing in phase 2 clinical studies of a novel brain-targeted anti-inflammatory drug candidate, VX-745, for the treatment of Alzheimer's disease (AD) 2EIP Pharma announces first patient dosing in phase 2 clinical studies of a novel brain-targeted anti-inflammatory drug candidate, VX-745, for the treatment of Alzheimer's disease (AD) 3European Ultrasound Devices Market Report 2015-2019 2
... May 4, 2012  PRO-DEX, INC. (NasdaqCM: PDEX) today announced ... months ended March 31, 2012. (Logo: ... reported a loss from continuing operations of $513,000, or ... 31, 2012 compared to income from continuing operations of ...
... (NASDAQ: AMGN ) will present at the Baird ... Four Seasons Hotel, Chicago, Ill., beginning at 8:20 a.m. Central ... Amgen, will present. Live audio of the presentation can be ... , under Investors. About Amgen ...
Cached Medicine Technology:Pro-Dex, Inc. Announces Fiscal Third Quarter and Nine Month Results 2Pro-Dex, Inc. Announces Fiscal Third Quarter and Nine Month Results 3Pro-Dex, Inc. Announces Fiscal Third Quarter and Nine Month Results 4Pro-Dex, Inc. Announces Fiscal Third Quarter and Nine Month Results 5Pro-Dex, Inc. Announces Fiscal Third Quarter and Nine Month Results 6Pro-Dex, Inc. Announces Fiscal Third Quarter and Nine Month Results 7Pro-Dex, Inc. Announces Fiscal Third Quarter and Nine Month Results 8
Designated most popular model or size. 3 mm tip....
Designated most popular model or size. Double-ended. 2 mm wide....
Designated most popular model or size. Slightly angled, 2 mm wide....
4 mm x 6 mm dissector end with shaft marked at 10 mm, 20 mm, 30 mm from tip. 6 mm wide curved elevator. Round knurled handle....
Medicine Products: