Navigation Links
Scientists identify gene that is consistently altered in obese individuals
Date:3/21/2013

r offspring. He believes that a lot of methylation starts in the womb and there are unfortunate real-life circumstances that support that theory.

For example, in the Dutch famine of 1944 near the end of World War II, babies born to starving mothers experienced DNA methylation that made them better able to survive such depravation, but in the more plentiful environment in which they grew up, put them at increased risk for cardiovascular disease as well as diabetes, obesity and other health problems.

He's already moving forward with more human studies as well, looking at a new group of lean and obese individuals, analyzing their DNA expression to see if increased methylation of LY86 means the gene is expressed more or less. Generally, higher methylation is thought to translate to lower gene expression.

He also wants to pin down whether methylation results from things like a high-fat diet, unfortunate genetics or both. These types of details may help explain why some individuals grow obese with a bad diet and little physical activity while others don't, Su said. It also may mean that positive environmental change, such as a better diet or more physical activity, can reverse at least some of the methylation. People may not get thin, for example, but they may reduce their risk for obesity-related disease, Su said.

LY86's clear importance in obesity emerged by first merging the gene list from the genome wide association studies with a genome wide methylation database on a small cohort of seven obese and seven lean individuals. The finding of increased methylation held up in subsequent groups of 46 obese/46 leans, 230 obese/413 leans as well as the general population panel of 703 at the GRU Institute of Public and Preventive Health. The research was supported by the National Institutes of Health.


'/>"/>

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Most men with erectile dysfunction remain untreated, say US scientists
2. Scientists investigate potential markers for a response to sunitinib in patients with metastatic RCC
3. Scientists ID Antibody That Might Boost Cancer Therapy
4. Scientists Report Clues to Flu Shots Effectiveness
5. Scientists discuss relationship between abortion and violence against women
6. A*STAR scientists discover switch critical to wound healing
7. Scientists uncover source of ovarian stem-like cells prone to give rise to ovarian cancer
8. Defective virus surprisingly plays major role in spread of disease, UCLA life scientists report
9. OHSU scientists first to grow liver stem cells in culture, demonstrate therapeutic benefit
10. Scientists Pinpoint How Deep Brain Stimulation Eases OCD
11. Scientists make older adults less forgetful in memory tests
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists identify gene that is consistently altered in obese individuals
(Date:9/2/2014)... 2014 IMCA Speedway Motors Super Nationals, ... September 1, 2014 at the IMCA Speedway in Boone, ... will include a check presentation to Hope For The ... a national nonprofit organization that assists post-9/11 service members, ... sustained physical and psychological wounds in the line of ...
(Date:9/2/2014)... Autumn is well under way ... the new season with worldwide people. Recently, it ... that Hostgator ( http://secure.hostgator.com/~affiliat/cgi-bin/affiliates/clickthru.cgi?id=seohosts ), Arvixe, and Bluehost ... , Since 2002 HostGator has been known ... company’s reputation for reliability remains with it today. ...
(Date:9/2/2014)... births out-of-hospital in Norway are associated with higher infant ... Gynecologica Scandinavica , a journal of the Nordic Federation ... women who have given birth at least once before ... likely to have unplanned deliveries, which may increase the ... close to 60,000 babies were born in Norway according ...
(Date:9/2/2014)... eye disease include the sensation of grit in the ... The causes are poorly understood., The researchers base their ... (average age 57) from the TwinsUK cohort, drawn from ... This cohort is widely regarded as representative of the ... at a wide range of diseases and genetic traits ...
(Date:9/2/2014)... PULLMAN, Wash. - Smoking today,s concentrated pot might ... research from Washington State University. The study is ... development of tolerance to THC. , Psychology ... estrogen levels, female rats are at least 30 ... qualities of THCthe key active ingredient in cannabis. ...
Breaking Medicine News(10 mins):Health News:IMCA to Present Donation to Hope For The Warriors 2Health News:Top10BestSEOHosting.com Celebrates The Coming Of Autumn And Release Reseller Hosting Suppliers Of 2014 2Health News:Unplanned births out-of-hospital increases risk of infant mortality 2Health News:Around 1 in 10 UK women has dry eye disease, requiring artificial tears 2Health News:Estrogen increases cannabis sensitivity 2Health News:Estrogen increases cannabis sensitivity 3
... that can cause meningitis, pneumonia in young children, , , ... said Thursday that a shortage of vaccine is leading ... important causes of bacterial illness in young children. , ... in cases, the stepped-up surveillance was prompted by a ...
... Nov. 20 Emerson Ecologics, LLC today,announced the ... TIDhealth, of Redlands, CA, a leading national distributor ... market. , ... leading U.S. provider,of integrative healthcare products and services ...
... the only,health plan in California to earn excellent, four-star ... the California Office of the,Patient Advocate (OPA). , ... announced today by the California OPA, also show,Kaiser Permanente ... in clinical quality among the nine health plans,surveyed. , ...
... Software by HP today announced the winners of its 2008 Visionary ... in Cincinnati, Ohio. , ... LEXINGTON, Ky. (Business ... that have used HP Exstream to make significant strides in improving ...
... China Shenghuo,Pharmaceutical Holdings, Inc. (NYSE Alternext US: ... consistent with its previous,announcements, it has filed with ... an amended Annual Report on Form 10-KSB/A for ... Report on Form 10-Q/A for the,first quarter ended ...
... America is pleased to,introduce Surgery Benefit Management to ... Healthplace Benefit(TM), is the first and only,comprehensive Surgery ... health plans while enhancing employee benefits with quality ... Surgery accounts for $700 billion of ...
Cached Medicine News:Health News:CDC Monitors Shortage of Hib Vaccine 2Health News:CDC Monitors Shortage of Hib Vaccine 3Health News:Emerson Ecologics Announces Acquisition of TIDhealth 2Health News:Emerson Ecologics Announces Acquisition of TIDhealth 3Health News:Kaiser Permanente Receives the Most Stars in California Office of Patient Advocate's Annual Quality Report Card 2Health News:Kaiser Permanente Receives the Most Stars in California Office of Patient Advocate's Annual Quality Report Card 3Health News: Exstream Software by HP Announces 2008 Visionary Award Winners : Customers Showcase Innovative Applications Created using the HP Exstream Enterprise Document Automation Solution 2Health News: Exstream Software by HP Announces 2008 Visionary Award Winners : Customers Showcase Innovative Applications Created using the HP Exstream Enterprise Document Automation Solution 3Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 2Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 3Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 4Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 5Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 6Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 7Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 8Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 9Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 10Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 11Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 12Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 13Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 14Health News:China Shenghuo Announces Restated Results For Full Year 2007 & First Quarter 2008, Reports Results For Second & Third Quarter 2008 15Health News:Healthplace America Delivers the First and Only Surgery Benefit Management Solution Through the Healthplace Benefit(TM) 2Health News:Healthplace America Delivers the First and Only Surgery Benefit Management Solution Through the Healthplace Benefit(TM) 3
(Date:9/2/2014)... 2, 2014 Reportlinker.com announces that a ... catalogue: Acute Heart Failure Global Clinical ... http://www.reportlinker.com/p0689743/Acute-Heart-Failure-Global-Clinical-Trials-Review-H2-2014.html Acute Heart Failure Global ... GlobalData,s clinical trial report, "Acute Heart Failure ... on the Acute Heart Failure clinical trial scenario. ...
(Date:9/2/2014)... , Sept. 2, 2014   Santa Clara ... offering a special promotion for Invisalign. Invisalign is an ... and wires. It is often the orthodontic treatment of ... convenience and aesthetics of it. For a limited time, ... a significant savings from the usual cost. This offer ...
(Date:9/2/2014)... September 2, 2014 ... ESC-Kongress 2014 präsentierte GARFIELD-AF-Register bietet einen ... von schlaganfallgefährdeten Patienten in der klinischen ... Daten der nahezu 12.500 ... und unabhängigen Forschungsinitiative zur Untersuchung von ...
Breaking Medicine Technology:Acute Heart Failure Global Clinical Trials Review, H2, 2014 2Acute Heart Failure Global Clinical Trials Review, H2, 2014 3Acute Heart Failure Global Clinical Trials Review, H2, 2014 4Acute Heart Failure Global Clinical Trials Review, H2, 2014 5Acute Heart Failure Global Clinical Trials Review, H2, 2014 6Acute Heart Failure Global Clinical Trials Review, H2, 2014 7Acute Heart Failure Global Clinical Trials Review, H2, 2014 8Santa Clara Cosmetic Dentist, Dr. Alan Frame, is Now Offering a Special on Invisalign 2Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 2Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 3Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 4Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 5Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 6Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 7Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 8Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 9Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 10Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 11
These flexible stone retrieval devices are reusable, 3 Fr in diameter, with a working length of either 60 cm or 115 cm...
... The definition of dexterity in ... to grip firmly and release easily, ... comfort and security. A three- or ... control during stone retrieval. These graspers ...
For rigid cystoscopes and rigid-, and semi-rigid ureteroscopes, these forceps have an integral handle design and a diameter of 5 Fr with a working length of 58 cm....
Used for the retrieval of stones, stents, or other objects in the urinary tract under direct vision. Retrieval Forceps are designed for use through rigid or flexible endoscopes. Supplied sterile in p...
Medicine Products: