Navigation Links
Scientists get first look at how water 'lubricates' proteins
Date:11/14/2007

COLUMBUS , Ohio -- Scientists are one step closer to understanding how proteins move when they perform functions essential for supporting life.

For the first time, scientists have directly observed how water lubricates the movements of protein molecules to enable different functions to happen.

In a paper published in the online early edition of the Proceedings of the National Academy of Sciences, Ohio State University researchers report using ultra-fast light pulses to reveal how water molecules link up with proteins and enable them to move and function.

The finding could one day help researchers find new treatments for diseases such as Alzheimer's, Parkinson's, cataracts, cystic fibrosis, and diabetes.

Proteins are complex molecules that form the main support structure for plant and animal cells, and they also regulate biochemical reactions. The shape and movements of a protein molecule determine its function, and scientists have long known that proteins can't function unless they are immersed in water.

Protein-water interactions are a central, long-standing, unsolved problem in protein science, said Dongping Zhong, associate professor of physics at Ohio State and leader of the study. We believe that we are making a major step to answer these fundamental questions, and the final results will be very important for many biological applications.

For instance, scientists could better understand how proteins fold and mis-fold -- a key to understanding certain diseases. They could also design more effective drug molecules that link up with proteins in just the right way.

Molecules move fast, shape-shifting in mere fractions of a second, so the movements are hard to see.

This study marks the first time scientists have been able to map the movements of water molecules at different sites on a much larger protein molecule, and see how those movements influence the form and function of the protein
'/>"/>

Contact: Dongping Zhong
Zhong.28@osu.edu
614-292-3044
Ohio State University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
2. Scientists Probe Sepsis Deadly Secrets
3. Scientists puzzled by severe allergic reaction to cancer drug in the middle Southern US
4. Scientists Develop Natural Protection for Stored Foods
5. Scientists detect presence of marburg virus in african fruit bats
6. Scientists Spot Brains Free Will Center
7. Scientists ID Likely Culprit in Popcorn Lung
8. Scientists explain how insulin secreting cells maintain their glucose sensitivity
9. Scripps Research scientists shed new light on how antibodies fight HIV
10. Scientists, physicians present latest findings in personalized cancer treatment and prevention
11. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... January 22, 2015 Gabe’s Chemo Duck Program is ... the first app ever created for kids with cancer. The Chemo ... and devices, is filled with enjoyable games to help children of ... The free app helps to keep kids entertained, educated and at ...
(Date:1/22/2015)... is a famous wedding dress company offering many trendy designs. ... Facebook, Twitter, and Pinterest. The fans will have an opportunity ... every week. , Moreover, the company has extended its 2015 ... homepage for more information. , Angelweddingdress is a ...
(Date:1/22/2015)... 22, 2015 Juvent Sports ( http://www.juventsports.com ... 2015 PGA Merchandise Show to bestow a Juvent Sports ... amateur golfer, Arlene McKitrick. The award commemorated and congratulated ... tournament win. She won her first amateur tournament in ...
(Date:1/22/2015)... 2015 For over 20 years, Dr. David Cruz ... Vista area has treated just about every type of injury ... And for those same twenty-plus years, the team at ... injuries with the best possible doctor. With the combined ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Yesterday, ... Bonilla (D-Concord) and Kristin Olsen (R-Modesto) were honored ... leadership in advancing biotechnology, biomedical science, medical device ... Olsen each received the “2014 Life Sciences Champion” ...
Breaking Medicine News(10 mins):Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3
... Blood ... Pressure Up to 30 Points, ... that the United States Food and Drug Administration (FDA),has approved ... known as high blood pressure. AZOR is a,convenient, once daily, ...
... to be higher than for whites, study finds , , THURSDAY, ... diabetes who take drugs to control their disease are less ... a new study finds. , Two factors appear to account ... to medications and emotional responses to having diabetes, according to ...
... QMED ) today announced it expects to report for ... of approximately $10.8 million and,$26.6 million and a net ... cash position as of August 31st, 2007 is,approximately $6.4 ... and CEO, said, "During the months of July and,August, ...
... the Largest and the ... Becomes McLaren,s Newest Subsidiary in Southeast ... Michigan, PONTIAC, Mich., Sept. ... care system in Michigan,McLaren Health Care is pleased to announce the addition of POH ...
... PARIS, Sept. 27 KARL LAGERFELD SAS announced ... to create KARL,LAGERFELD men,s and women,s eyewear starting ... one of the most prominent eyewear companies,the exclusive ... sun and ophthalmic collections for the KARL LAGERFELD ...
... WASHINGTON, Sept. 27 - 100 Black Men of,America, Inc. ... that,will work to increase local outreach to diverse communities ... to enhance,delivery of services to diverse communities during times ... the agreement the Red Cross will provide disaster training ...
Cached Medicine News:Health News:AZOR(TM) Receives FDA Approval for Treatment of High Blood Pressure 2Health News:AZOR(TM) Receives FDA Approval for Treatment of High Blood Pressure 3Health News:AZOR(TM) Receives FDA Approval for Treatment of High Blood Pressure 4Health News:AZOR(TM) Receives FDA Approval for Treatment of High Blood Pressure 5Health News:AZOR(TM) Receives FDA Approval for Treatment of High Blood Pressure 6Health News:Older Blacks, Latinos Struggle With Diabetes Control 2Health News:Older Blacks, Latinos Struggle With Diabetes Control 3Health News:QMed, Inc. Comments on Estimated 3rd Quarter Results & Medical Expense Ratio; Sets 2008 Revenue Guidance for Medicare SNPs at $88-95 Million 2Health News:QMed, Inc. Comments on Estimated 3rd Quarter Results & Medical Expense Ratio; Sets 2008 Revenue Guidance for Medicare SNPs at $88-95 Million 3Health News:McLaren Health Care Adds POH Medical Center to System 2Health News:KARL LAGERFELD SAS Signs Global Eyewear License Agreement With Marchon Eyewear, Inc. 2Health News:100 Black Men of America, Inc. and American Red Cross Sign National Agreement to Increase Diverse Outreach Nationwide 2
(Date:1/23/2015)... , Jan. 23, 2015  Immune Therapeutics, Inc. today announced the ... the compounding, packaging and distributing of its naltrexone tablets.  The ... United States . KRS Global is ... tablets in various strengths for individual patients in response to ...
(Date:1/23/2015)... 2015  iMD Companies, Inc. (ICBU) has repositioned itself as a ... grab a foothold in the hydroponic, hemp and medical marijuana ... presence in the sector, and recently partnering with the Chippewa ... and medical marijuana, iMD is committing to bring its vision ...
(Date:1/23/2015)... , Jan. 23, 2015  Mallinckrodt plc (NYSE: ... has approved a share repurchase program. The open-ended authorization ... of Mallinckrodt plc ordinary shares. "Funding ... top priorities as we continue to pursue a range ...
Breaking Medicine Technology:Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 3Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 4iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4
... SAN DIEGO, Oct. 28 Neurocrine Biosciences, Inc. (Nasdaq: NBIX ... 30, 2009. For the third quarter of 2009, the Company reported ... with a net loss of $17.7 million, or $0.46 per share, ... September 30, 2009, the Company reported a net loss of $43.1 ...
... BATESVILLE, Ind., Oct. 28 Hill-Rom Holdings, Inc. (NYSE: ... and 2010 financial guidance on Wednesday, November 11, 2009. ... morning on Thursday, November 12, 2009 at 7:30 a.m. EST. ... Quarter Earnings and 2010 Financial Guidance release will be issued ...
Cached Medicine Technology:Neurocrine Biosciences Reports Third Quarter 2009 Results 2Neurocrine Biosciences Reports Third Quarter 2009 Results 3Neurocrine Biosciences Reports Third Quarter 2009 Results 4Neurocrine Biosciences Reports Third Quarter 2009 Results 5Neurocrine Biosciences Reports Third Quarter 2009 Results 6Neurocrine Biosciences Reports Third Quarter 2009 Results 7Neurocrine Biosciences Reports Third Quarter 2009 Results 8Hill-Rom Holdings, Inc. Invites You to Join Its Fiscal 2009 Fourth Quarter Earnings and 2010 Financial Guidance Webcast 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: