Navigation Links
Scientists far from finish line in understanding anemia in female athletes
Date:11/20/2013

ANN ARBORWhen Kaitlyn Patterson's fatigue progressed to hyperventilating even during slow runs, and then forced her to quit high school distance running for the season, she knew something was very wrong.

Patterson had exercise-induced iron-deficiency anemia, a common, perplexing problem among elite female athletes, especially endurance runners. Later, as a University of Michigan sophomore, she was so interested in the topic that she applied for an undergraduate research position in the lab of Peter Bodary, U-M clinical assistant professor of movement science and health & fitness.

Patterson recently co-wrote a study challengingand perhaps putting to resta popular hypothesis on what causes exercise-induced iron-deficiency anemia.

It's another in a succession of findings from separate research groups that debunk the notion that the iron-regulating hormone hepcidin causes exercise-induced anemia. Conventional science has suggested that rigorous exercise causes hepcidin spikes that result in anemia.

"The U-M finding is significant because we want to provide physicians with the most accurate information regarding exercise-induced anemia," Bodary said.

The downside is that hepcidin isn't the anemia cure-all the scientific community had hoped.

Bodary said that physicians already do a nice job of helping athletes recover from exercise-induced anemia by providing iron supplementation and educating athletes about optimizing iron absorption. The challenge now is understanding what causes anemia in order to prevent it.

The U-M study is the first known to compare hepcidin levels in competitive college female runners against those of non-exercisers, Bodary said. About half the runners in the study had a history of anemia and about 85 percent supplemented with iron.

Researchers wanted to see if hepcidin remained high in resting athletes, which could link elevated hepcidin with exercise-induced iron-deficiency anemia. However, overall hepcidin levels in both groups were about equal, Bodary said.

Will scientists have to return to the starting line? Not necessarily. A physician familiar with Bodary's research contacted him about a female patient with long-term anemia that is hypothesized to have elevated levels of resting hepcidin. Although she didn't exercise regularly, her blood work resembled that of an athlete with the disease, Bodary said.

By analyzing the woman's blood samples, Bodary's lab hopes to learn if high hepcidin drives her anemia. Results could help scientists decode what causes anemia in both the general population of women and in elite athletes.

Meanwhile, Patterson remains healthy since her first struggles with anemia.

"I still run, and have returned to cross country skiing and have taken up cycling," she said. "I'm planning on ski racing this winter and putting together a solid triathlon season. I've been fortunate in that I responded well to iron supplementation, so I've stayed healthy since my original bout with anemia."


'/>"/>

Contact: Laura Bailey
baileylm@umich.edu
734-647-1848
University of Michigan
Source:Eurekalert

Related medicine news :

1. LSUHSC faculty shares inside knowledge in book to develop nations research scientists
2. Renowned Scientists Join Cure Alzheimer’s Fund’s Search for Alzheimer’s Therapies
3. Scientists fingerprint single cancer cells to map cancers family tree
4. A*STAR scientists bring to light mechanism of drug for infections
5. NSF International Scientists Announce Discovery of New Bacterium, Same Family as E. coli and Klebsiella Pneumonia
6. CNIO scientists decipher how the immune system induces liver damage during hepatitis
7. A*STAR scientists uncover potential drug target to nip cancer in the bud
8. Volunteers join scientists in finding out who gets rid of cow dung
9. Scientists at Cancer Prevention Institute of California Find That a Diet High in Fruits and Vegetables May Significantly Reduce Risk of Breast Cancer
10. Leicester scientists map structure of key complex in the immune system
11. Neuroscientists determine how treatment for anxiety disorders silences fear neurons
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in agile ... a contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise ... use of Agile methodologies in a consistent and high value manner across CMS ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent ... sleep apnea using cutting-edge Oventus O2Vent technology. As many as 18 million ... by frequent cessation in breathing. Oral appliances can offer significant relief to about ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... The American ... Excellence to Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium ... 8. , In honor of Morris F. Collen, a pioneer in the field of ...
(Date:10/12/2017)... ... ... HMP , a leader in healthcare events and education, today announced that ... for ‘Best B-to-B Healthcare Website.’ Winners were announced during the Eddie & Ozzie Awards ... recognizes editorial and design excellence across a range of sectors. This year’s program included ...
(Date:10/12/2017)... ... October 12, 2017 , ... Health ... interactive health literacy software tool, and the Cancer Patient Education Network (CPEN), an ... education, today announce a new strategic alliance. , As CPEN’s strategic partner, ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... , Sept. 22, 2017  As the latest ... Senators Bill Cassidy (R-LA) and Lindsey ... notes that the medical device industry is in an ... device tax, the 2.3% excise tax on medical device ... they also want covered patients, increased visits and hospital ...
(Date:9/19/2017)... 2017 HistoSonics, Inc., a venture-backed medical device company developing a non-invasive, robotically assisted, ... three leadership team developments today:   ... ... Tom Tefft ... Veteran medical device executive Josh Stopek , PhD, who has ...
(Date:9/18/2017)... Mich. , Sept. 18, 2017  PMD Healthcare ... Specialty Pharmacy of Kalamazoo, Mich. , ... hub service that expedites and streamlines patient and provider ... PD 2.0, and wellness management services.  ... device used to measure lung function for a variety ...
Breaking Medicine Technology: