Navigation Links
Scientists explore new class of synthetic vaccines
Date:7/25/2012

In a quest to make safer and more effective vaccines, scientists at the Biodesign Institute at Arizona State University have turned to a promising field called DNA nanotechnology to make an entirely new class of synthetic vaccines.

In a study published in the journal Nano Letters, Biodesign immunologist Yung Chang joined forces with her colleagues, including DNA nanotechnology innovator Hao Yan, to develop the first vaccine complex that could be delivered safely and effectively by piggybacking onto self-assembled, three-dimensional DNA nanostructures.

"When Hao treated DNA not as a genetic material, but as a scaffolding material, that made me think of possible applications in immunology," said Chang, an associate professor in the School of Life Sciences and a researcher in the Biodesign Institute's Center for Infectious Diseases and Vaccinology. "This provided a great opportunity to try to use these DNA scaffolds to make a synthetic vaccine."

"The major concern was: Is it safe? We wanted to mimic the assembly of molecules that can trigger a safe and powerful immune response in the body. As Hao's team has developed a variety of interesting DNA nanostructures during the past few years, we have been collaborating more and more with a goal to further explore some promising human health applications of this technology."

The core multidisciplinary research team members also included: ASU chemistry and biochemistry graduate student and paper first author Xiaowei Liu, visiting professor Yang Xu, chemistry and biochemistry assistant professor Yan Liu, School of Life Sciences undergraduate Craig Clifford and Tao Yu, visiting graduate student from Sichuan University.

Chang points out that vaccines have led to the some of the most effective public health triumphs in all of medicine. The state-of-the-art in vaccine development relies on genetic engineering to assemble immune system stimulating proteins into virus-like p
'/>"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. New method to find novel connections from gene to gene, drug to drug and between scientists
2. Scientists discover melanoma-driving genetic changes caused by sun damage
3. Scientists Map Genomes of One Mans Sperm
4. Scientists Say Blood Test May Help Predict Alzheimers
5. Scientists find new way to induce programmed cell death, or apoptosis
6. New York Stem Cell Foundation scientists featured for new model of Alzheimers disease
7. SIgN scientists discover dendritic cells key to activating human immune responses
8. UW scientists discover why human body cannot fight HIV infection
9. Scientists Pinpoint Antibody That May Be Specific to MS Patients
10. Scientists first to see trafficking of immune cells in beating heart
11. Scientists develop new strategy to overcome drug-resistant childhood cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists explore new class of synthetic vaccines
(Date:5/22/2015)... According to a new Aegis Living Study on ... likely to worry about what will happen to their memory ... 69% Silent Generation), which may help explain why nearly half ... particularly Millennials (47%), Gen X’ers (51%), and Boomers (43%). The ... among more than 2,000 U.S. adults ages 18+. , ...
(Date:5/22/2015)... 2015 The dentist in ... that they are now offering complimentary consultations to ... treatments. At consultations, patients can discuss their candidacy ... certain treatments can achieve and whether alternative options ... initial appointment. If treatments are chosen, patients can ...
(Date:5/22/2015)... 22, 2015 Wimbledon Health Partners, the ... (EKG), echocardiogram and NCV testing , is proud ... respected All American National athlete, to the Wimbledon Athletics ... the high level of testing and information it provides ... their athletic trainers, this way they can focus on ...
(Date:5/22/2015)... In April 2006, Veatch Consulting opened for ... they have concentrated their focus to working with over ... of this growth and their goals to better serve ... Colorado, Cleveland, Ohio, Houston, Texas and now Dallas, Texas. ... offices, dental start ups, orthodontic practices, pediatric dental practices, ...
(Date:5/22/2015)... 22, 2015 In efforts to offer ... section containing particular muscles stretches has been a large ... of stretches now complete, Chunk Fitness envisions a mid-June ... be filmed and released at a later point in ... here: http://www.chunkfitness.com/stretches . , About the Company: Chunk ...
Breaking Medicine News(10 mins):Health News:New Study Reveals America’s Fear of Aging 2Health News:New Study Reveals America’s Fear of Aging 3Health News:West Hollywood Dental Office, Sunset Plaza Dental is Now Offering Complimentary Consultations 2Health News:Wimbledon Athletics Recruits Team USA Athlete 2Health News:Wimbledon Athletics Recruits Team USA Athlete 3
... paramedics shortens time to specialized treatment, study finds , ... people with chest pain who are given an electrocardiogram ... long to receive treatment to open their arteries. , ... and go directly to the cardiac catheterization laboratory for ...
... ... Flying Aid and Orange Israel Telecommunications have announced today that they are aiding ... children. This will be the first of three stages of establishing the orphanage ... IDF - will be providing fresh, running drinking water, an electric generator, tents ...
... less likely to opt for surgery than county hospitals, ... The type of treatment received by prostate cancer patients ... where they receive care, a new U.S. study has ... in county hospitals, while patients in private facilities ...
... , WASHINGTON , Jan. 25 ... disability advocates, The HSC Foundation is currently accepting applications for its ... the ages of 14 and 26 in the Washington, DC ... , Applicants will be evaluated on their current and previous work ...
... , ... OrthoAccel Technologies, Inc., developers of the AcceleDent System , ... week that it has engaged Waldemar "Val" B. Szwajkowski ... the Company will be primarily focused on strategic development of ...
... ... 5W Public Relations ( http://www.5wpr.com ) , one of the 25 ... of Philip Stein ( http://www.philipstein.com/ ) watches to its versatile roster ... quickly grown to be a leader in watches and other lifestyle products using ...
Cached Medicine News:Health News:Israel Flying Aid, Orange Israel Create Haiti Orphanage, Provide Humanitarian Aid 2Health News:Israel Flying Aid, Orange Israel Create Haiti Orphanage, Provide Humanitarian Aid 3Health News:Israel Flying Aid, Orange Israel Create Haiti Orphanage, Provide Humanitarian Aid 4Health News:Prostate Cancer Care Varies By Hospital Type 2Health News:DC Nonprofit Searches for Next Generation of Disability Advocates 2Health News:Industry Advisor Joins OrthoAccel Technologies, Inc. 2Health News:Industry Advisor Joins OrthoAccel Technologies, Inc. 3Health News:Industry Advisor Joins OrthoAccel Technologies, Inc. 4Health News:5W Public Relations Adds Philip Stein Watches to Its Fashion & Lifestyle Client Roster 2Health News:5W Public Relations Adds Philip Stein Watches to Its Fashion & Lifestyle Client Roster 3
(Date:5/22/2015)... 22, 2015 According to a ... Product (Consumables, Instruments, Services), by Test Type (Indirect, Enzyme-based, ... Cytometry), by End Users - Global Forecast to 2020", ... expected to reach $736.85 Million by 2020 from $452.36 ... Browse 71 market data Tables and ...
(Date:5/22/2015)... BOSTON , May 22, 2015   InspireMD, Inc. ... in stent embolic protection systems ("EPS"), today announced that its ... PARADIGM, lead by principle investigator Prof. Piotr Musialek , ... in Paris, France . PARADIGM, ... pe R cutaneous c A roti D revascularization ...
(Date:5/22/2015)... R.I. , May 22, 2015 ... once-daily central nervous system stimulant indicated for the ... to patients beginning Summer 2015. ... XR received approval from the U.S. Food and ... is an extended-release formulation of methylphenidate capsule with ...
Breaking Medicine Technology:Oxidative Stress Assays Market Worth $736.85 Million by 2020 2Oxidative Stress Assays Market Worth $736.85 Million by 2020 3Oxidative Stress Assays Market Worth $736.85 Million by 2020 4InspireMD's CGuardTM Highlighted at Clinical Presentation at EuroPCR 2015 Conference 2InspireMD's CGuardTM Highlighted at Clinical Presentation at EuroPCR 2015 Conference 3InspireMD's CGuardTM Highlighted at Clinical Presentation at EuroPCR 2015 Conference 4Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 2Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 3Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 4Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 5Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 6
... false signals and contamination caused by ... Barrier Tips offer performance and economy ... (PCR(a)), radioactive isotopes, tissue culture fluids, ... , ,Promega Barrier Tips are made ...
... ART Aerosol Resistant Tips offer a ... ART Tips are designed for applications such ... studies. In addition, ART Tips are excellent ... and forensic studies. ART Tips prevent aerosol ...
Ideal for use with low volume samples on the Biomek robotic pipetting systems, the ART 20R provides guaranteed protection for your expensive workstation....
Hydrophobic PE filter without self-sealing additives, permits sample recovery after accidental over-pipetting. All filters are sterile (to USP, DAB, Ph.Eur. standards) and PCR clean (free from human ...
Medicine Products: