Navigation Links
Scientists discover new mechanism regulating the immune response
Date:6/28/2013

Scientists at an Academy of Finland Centre of Excellence have discovered a new mechanism regulating the immune response that can leave a person susceptible to autoimmune diseases.

A fresh study by Turku Centre for Biotechnology and Aalto University in Finland is the first to report a new mechanism that regulates specification of lymphocytes, the white blood cells pivotal to immune response. By combining state-of-the art techniques, next-generation deep sequencing and computational data mining, the researchers discovered new epigenetic factors regulating lymphocyte function. Regulatory regions of the genes studied displayed variations (single nucleotide polymorphisms or SNPs) that have been associated with predisposition to autoimmune diseases such as type1 diabetes, rheumatoid arthritis and inflammatory bowel disease. These discoveries provide new insight into and basis for the study of emergent mechanisms of immune-mediated diseases.

Immune-mediated diseases such as type 1 diabetes, rheumatoid arthritis, asthma and allergies result from abnormal immune response. T lymphocytes that orchestrate the immune response can differentiate into functionally distinct lineages to combat infection and disease. The correct response to cytokines and a controlled balance of T lymphocyte populations are critical for the immune system and for the avoidance of autoimmune disorders.

The study was published in Immunity, a distinguished international scientific journal.


'/>"/>

Contact: Riitta Lahesmaa
riitta.lahesmaa@btk.fi
358-233-38601
Academy of Finland
Source:Eurekalert

Page: 1

Related medicine news :

1. Scientists solving the mystery of human consciousness
2. Scientists uncover multiple faces of deadly breast cancer
3. Scientists identify major source of cells defense against oxidative stress
4. Scientists tailor cell surface targeting system to hit organelle ZIP codes
5. Scientists rewrite rulebook on breast cancer in landmark global study
6. Warwick scientists uncover how checkpoint proteins bind chromosomes
7. NIH scientists link quickly spreading gene to Asian MRSA epidemic
8. Joslin scientists identify important mechanism that affects the aging process
9. Scripps Research scientists show how memory B cells stay in class to fight different infections
10. Scientists Map Melanomas Genome
11. A*STAR scientists discover switch to boost anti-viral response to fight infectious diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... Raleigh, NC (PRWEB) August 21, 2014 ... proteins produced by Staph bacteria has been used to ... just posted an article on the new research. ... at the University of Western Australia treated mesothelioma ... that it killed the cancer cells while simultaneously stimulating ...
(Date:8/21/2014)... Obispo, CA (PRWEB) August 21, 2014 ... of Current Pedorthics, a bi-monthly publication of the Pedorthic Footcare ... of pedorthics. , Bunion Bootie is ... alternative solution for bunion sufferers and their pain. It is ... in nearly any shoe to eliminate the friction and rubbing ...
(Date:8/21/2014)... 21, 2014 According to a recent ... Ophthalmology, environmental factors may outweigh genetics in the development and ... of the world’s population is nearsighted, and this study provides ... “This is an important finding in the field of ophthalmology,” ... are we finding better ways to treat ophthalmological conditions ...
(Date:8/21/2014)... 21, 2014 Beverly Hills Medical Center of ... to offer patients TearLab, a new diagnostic option for measuring ... eye syndrome. , “ TearLab is a revolutionary new ... can accurately measure the amount of tears a patient produces ... Dr. Ghassan Zein, Medical Director at the Kuwait medical center. ...
(Date:8/21/2014)... Beverly Hills, CA (PRWEB) August 21, 2014 ... for your overall health. Juice cleanses offer clearer skin, more ... overall immune function. Pearl Recovery Retreat, a wellness center in ... programs right from the comfort of their recovery room. ... options to get them well again following surgery in our ...
Breaking Medicine News(10 mins):Health News:Study Finds Bacteria Compound Shrinks Mesothelioma Tumors, According to Surviving Mesothelioma 2Health News:Recently Featured in Current Pedorthics: Bunion Bootie, the Very Popular Bunion Treatment Splint 2Health News:Recently Featured in Current Pedorthics: Bunion Bootie, the Very Popular Bunion Treatment Splint 3Health News:Study Suggests Environmental Factors May Outweigh Genetics When It Comes to Myopia 2Health News:Beverly Hills Kuwait is the First Medical Center in Kuwait with Access to TearLab 2Health News:Los Angeles Surgery Recovery Center Now Offering Juice Cleanses 2Health News:Los Angeles Surgery Recovery Center Now Offering Juice Cleanses 3
... Corporation,("WorldHeart", Nasdaq: WHRT ), a pioneer in ... Alexander ("Alex") Martin as,President and CEO. Mr. Martin ... Mr. Martin joins WorldHeart from Edwards Lifesciences where ... Vice President since,2004. Previously, Alex was with Cordis ...
... Site Uses Search to Improve Point-of-Care Decisions ... leader in enterprise search, recently published a ... Platform(TM) helps health-care practitioners deliver faster and ... The case study details Vivisimo,s application for ...
... cancer risk almost 6-fold, researchers find , , FRIDAY, Feb. ... mutations that appear to predict a significant increased risk ... to early diagnosis and treatment, the researchers said. In ... and 1,590 deaths, according to the U.S. National Cancer ...
... University at Buffalo researcher John Violanti, Ph.D., a specialist ... a study on suicide risk among returning veterans. The ... number of soldiers taking their own lives., Violanti currently ... quickly persons associate feelings of self-harm, as a way ...
... Feb. 6 Masimo Corporation (Nasdaq: MASI ... and Low-Perfusion pulse oximetry, today announced that its management ... 21st Annual OC Growth Stock Conference at The Ritz-Carlton, ... 18, 2009, at 11:00 a.m. PT. A live audiocast ...
... Feb. 6 Optimal Reading Services Group, ... hospitals and radiology group practices, announced that its chief ... UBS Global Healthcare Services Conference on Monday, February 9, ... Hotel in New York City.Optimal leverages a deep pool ...
Cached Medicine News:Health News:WorldHeart Appoints New President and CEO 2Health News:WorldHeart Appoints New President and CEO 3Health News:New Vivisimo Case Study Details Medical Search 2Health News:Gene Test Could Predict Thyroid Cancer Risk 2Health News:Gene Test Could Predict Thyroid Cancer Risk 3Health News:Masimo to Present at the Roth Capital Partners 21st Annual OC Growth Stock Conference 2Health News:Optimal Readings to Present at 2009 UBS Global Healthcare Services Conference 2
(Date:8/20/2014)... LUTHERVILLE, Md. , Aug. 20, 2014 /PRNewswire/ ... (NADDI) today lauded the latest results achieved by ... system, known as the National Precursor Log Exchange ... law enforcement officials track down meth offenders and ... technology in Kansas blocked ...
(Date:8/20/2014)... Reportlinker.com announces that a new market ... The Impact of Healthcare Reform (PPACA) On ... http://www.reportlinker.com/p01618927/The-Impact-of-Healthcare-Reform-PPACA-On-the-US-IVD-Industry.html The "Patient Protection and ... that affects virtually every aspect of health care, ... take effect now. IVD manufacturers who have different ...
(Date:8/20/2014)... DUBLIN , Aug. 20, 2014 ... addition of the "Global Biosimilars/Follow-on-Biologics Market (Technology, ... 2013 - 2020" report to their offering. ... biosimilars/follow-on-biologics market (types, applications and geography) - Size, ... Research, Report, Opportunities, Segmentation and Forecast, 2013 - ...
Breaking Medicine Technology:Kansas's Stop-Sale System Achieves Significant Results In Battle Against Meth 2The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 2The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 3The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 4The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 5The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 6Global Biosimilars/Follow-on-Biologics Market (Technology, Types, Applications, Services and Geography) - Research Report, 2013 - 2020 2
... CITY , April 28 Sonic Innovations, Inc. (Sonic), the ... conducting ongoing training events for government clinicians.  The company has just completed ... San Diego, California and April 25 through 27 in ... 3 through 5 in Salt Lake City, Utah , ...
... April 28 The Wireless-Life Sciences Alliance ... its Wireless Health Commercialization Day on May 13, 2010 ... Convergence Summit, a three-day conference sponsored by the premier trade ... wireless communications technologies. The conference is scheduled for May ...
Cached Medicine Technology:Sonic Innovations Conducts National Training Events for Government Clinicians 2Sonic Innovations Conducts National Training Events for Government Clinicians 3Thought Leaders Shaping the Emerging Wireless Life Science Space to Share Vision and Insights at WLSA Convergence Summit 2Thought Leaders Shaping the Emerging Wireless Life Science Space to Share Vision and Insights at WLSA Convergence Summit 3Thought Leaders Shaping the Emerging Wireless Life Science Space to Share Vision and Insights at WLSA Convergence Summit 4
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: