Navigation Links
Scientists discover new clues explaining tendon injury

Tendon disorders cost the UK economy more than 7bn a year and now scientists at Queen Mary, University of London have identified a vital component of tendons which could help treat them.

The research, published in the highly regarded Royal Society journal Interface today (4 July), found that a component of tendons known as the interfascicular matrix (IFM) is essential for their function.

"Tendon disorders are highly debilitating and painful, and may herald the end of an Olympic athlete's career," said co-author Dr Hazel Screen, a senior lecturer in medical engineering at Queen Mary, University of London.

"Even today, with advancements in sports science, little is known about tendon health management, and we still do not understand why some people are more prone to tendon injury than others.

However, we have now found that the matrix which binds the fascicles together in the tendon, the IFM, is essential for tendon function and that changes to this structure may be responsible for tendon injury."

Scientists at Queen Mary, along with colleagues from University of Liverpool and University College London, are working on a project funded by the Horserace Betting Levy Board, in which they have been dissecting tendons from horses in order to better understand the role of the IFM.

Tendon injury is common in horses as well as humans, with an economic impact of more than 3bn a year in horse racing. Around 16,000 horses are in training each year and the tendon injury rate is as high as 43% with few horses returning to racing after injury.

Lead author Dr Chavaunne Thorpe from the School of Engineering and Materials Science at Queen Mary, University of London explained: "A specific tendon in horses known as the superficial digital flexor tendon (SDFT) stretches and recoils in the same way as the Achilles tendon and is injured in the same way.

"We tested how the components within the SDFT worked to enable the tendon to stretch and function effectively.

"When we looked at its capacity to stretch, we found that the IFM, previously thought to be unimportant in tendon function, was essential to SDFT extension in horses. We found that tendons with a stiffer IFM were not able to stretch as far before they failed."

The finding suggests that the IFM may be critical in preventing tendon overuse injury, and the authors are now trying to find out exactly how this is achieved.

Dr Screen added: "If we are able to manipulate the IFM, we could potentially design a diagnostic test to see whether someone is more susceptible to tendon injury than others, and also pave the way for prospective treatments."


Contact: Bridget Dempsey
Queen Mary, University of London

Related medicine news :

1. Scientists identify new cancer stem cell mechanism
2. Finding brings scientists 1 step closer to Parkinsons drug
3. Even Some Scientists Are Math-Challenged
4. Danish scientists detect new immune alert signal
5. Scientists discover mechanism that promotes lung cancer growth and survival
6. Scientists Probe Diversity of Human Bodys Microbes
7. Proposed testosterone testing of some female olympians challenged by Stanford scientists
8. Scientists identify possible drug target for acute pancreatitis
9. Scientists Map the Tomatos Genome
10. Scientists discover gene which causes rare disease in babies
11. Scientists evaluate different antimicrobial metals for use in water filters
Post Your Comments:
(Date:10/13/2017)... , ... October 13, 2017 , ... The Visiting Nurse ... Market. Featuring a collection of specialty vendors and unique items from across the nation, ... quality-focused health and wellness services offered by the VNA. The boutique will be ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Agile Software Development, has been awarded a contract by the Center for Medicare ... (BPA) aims to accelerate the enterprise use of Agile methodologies in a consistent ...
(Date:10/12/2017)... ... 12, 2017 , ... Planet Fitness, one of the largest and fastest growing ... open a flagship location in Covington, LA at 401 N. U.S. Highway 190, in ... to Office Depot in the Holiday Square shopping center. Its location allows it to ...
(Date:10/12/2017)... Rockville, Maryland (PRWEB) , ... October 12, 2017 ... ... a magnetic drug delivery system that we intend to develop to enable prevention ... regimens can lead to severe hearing loss, especially in pediatric patients. For cisplatin, ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... one of Michigan’s 2017 Best and Brightest in Wellness® by Best and Brightest. ... awards program on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... Texas , Oct. 6, 2017   Provista, ... with more than $100 billion in purchasing power, today ... news and information. The Newsroom is the ... and industry trends, infographics, expert bios, news releases, slideshows ... having access to a wealth of resources at their ...
(Date:10/4/2017)... to the Centers for Disease Control and Prevention (CDC), influenza vaccination ... is helping communities across Massachusetts , Connecticut ... flu shots through the end of the month. *Some exclusions ... ... shot is by the end of October, according to the Centers for ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: