Navigation Links
Scientists discover new clues explaining tendon injury
Date:7/4/2012

Tendon disorders cost the UK economy more than 7bn a year and now scientists at Queen Mary, University of London have identified a vital component of tendons which could help treat them.

The research, published in the highly regarded Royal Society journal Interface today (4 July), found that a component of tendons known as the interfascicular matrix (IFM) is essential for their function.

"Tendon disorders are highly debilitating and painful, and may herald the end of an Olympic athlete's career," said co-author Dr Hazel Screen, a senior lecturer in medical engineering at Queen Mary, University of London.

"Even today, with advancements in sports science, little is known about tendon health management, and we still do not understand why some people are more prone to tendon injury than others.

However, we have now found that the matrix which binds the fascicles together in the tendon, the IFM, is essential for tendon function and that changes to this structure may be responsible for tendon injury."

Scientists at Queen Mary, along with colleagues from University of Liverpool and University College London, are working on a project funded by the Horserace Betting Levy Board, in which they have been dissecting tendons from horses in order to better understand the role of the IFM.

Tendon injury is common in horses as well as humans, with an economic impact of more than 3bn a year in horse racing. Around 16,000 horses are in training each year and the tendon injury rate is as high as 43% with few horses returning to racing after injury.

Lead author Dr Chavaunne Thorpe from the School of Engineering and Materials Science at Queen Mary, University of London explained: "A specific tendon in horses known as the superficial digital flexor tendon (SDFT) stretches and recoils in the same way as the Achilles tendon and is injured in the same way.

"We tested how the components within the SDFT worked to enable the tendon to stretch and function effectively.

"When we looked at its capacity to stretch, we found that the IFM, previously thought to be unimportant in tendon function, was essential to SDFT extension in horses. We found that tendons with a stiffer IFM were not able to stretch as far before they failed."

The finding suggests that the IFM may be critical in preventing tendon overuse injury, and the authors are now trying to find out exactly how this is achieved.

Dr Screen added: "If we are able to manipulate the IFM, we could potentially design a diagnostic test to see whether someone is more susceptible to tendon injury than others, and also pave the way for prospective treatments."


'/>"/>

Contact: Bridget Dempsey
b.dempsey@qmul.ac.uk
44-207-882-3004
Queen Mary, University of London
Source:Eurekalert

Related medicine news :

1. Scientists identify new cancer stem cell mechanism
2. Finding brings scientists 1 step closer to Parkinsons drug
3. Even Some Scientists Are Math-Challenged
4. Danish scientists detect new immune alert signal
5. Scientists discover mechanism that promotes lung cancer growth and survival
6. Scientists Probe Diversity of Human Bodys Microbes
7. Proposed testosterone testing of some female olympians challenged by Stanford scientists
8. Scientists identify possible drug target for acute pancreatitis
9. Scientists Map the Tomatos Genome
10. Scientists discover gene which causes rare disease in babies
11. Scientists evaluate different antimicrobial metals for use in water filters
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... Los Angeles, CA (PRWEB) , ... February 08, 2016 , ... ... autism conference held annually in this country. The AutismOne 2016 Conference, which is being ... the truth they often won’t hear elsewhere about helpful interventions and causes of chronic ...
(Date:2/7/2016)... ... February 07, 2016 , ... ... the latest techniques and the most minimally invasive approaches. , Women who have ... after menopause. Other risk factors include surgery to the pelvic floor, connective tissue ...
(Date:2/7/2016)... (PRWEB) , ... February 07, 2016 , ... ... MyDecision™ program. MyDecision™ empowers employers and organizations with the tools and information to ... combines three elements to cut the cost of providing employee healthcare benefits by ...
(Date:2/6/2016)... ... February 06, 2016 , ... ... PERIOPERATIVE NURSES EXPECTED AT AORN SURGICAL CONFERENCE & EXPO , WHAT:     , ... with an estimated 5000 perioperative nurses in attendance to study the latest ...
(Date:2/6/2016)... CA (PRWEB) , ... February 06, 2016 , ... With ... and easily add warm color grades to their footage. A LUT is a Lookup ... pixel's color to the corresponding color indicated by the table. By manipulating each pixel, ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... 8, 2016  Labvantage Lx, a newcomer to ... male sexual enhancement product, EnduramenT. Setting a new ... with a patented biomedical breakthrough molecule that promotes ... compound responsible for many biological functions including erectile ... Forgoing the use of prescription medications, scientists ...
(Date:2/8/2016)... , Feb. 8, 2016  Echo Therapeutics, ... device company focused on non-invasive continuous glucose ... today announced that it will host a ... 17, 2015 at 9:00 a.m. Eastern Time ... its corporate strategy, advancements in its CGM ...
(Date:2/8/2016)... 2016 In a historic vote among its members this weekend, ... medical cannabis cultivation facility and dispensary on tribal land near ... as a provider for patients in the state,s Medical Cannabis Program. ... a provider for patients in the state,s Medical Cannabis Program. ... the project and pursue designation from the State of New ...
Breaking Medicine Technology: