Navigation Links
Scientists discover how to improve immune response to cancer at Princess Margaret Hospital
Date:4/26/2009

(Toronto April 26, 2009) A team of scientists at The Campbell Family Institute for Breast Cancer Research (CFIBCR) at Princess Margaret Hospital and international collaborators have discovered how to trigger an improved immune response to cancer that could be included in new clinical trials that use a patient's own cells to destroy tumours.

The findings, published online today in Nature Medicine (DOI: 10.1038/nm.1953), demonstrate the tantalizing potential of immunotherapy in cancer treatment, says principal investigator Dr. Pamela Ohashi, co-director, CFIBCR.

In the lab study, the scientists combined interleukin-7 (IL-7) a key component of the immune system with a viral vaccine to improve the ability of the cells of the immune system to attack tumours. The result was clear: The combination boosted immunity to tumours.

"We are extremely excited because our research has revealed the unexpected ways IL-7 works to break down barriers that naturally block the immune response to tumours. This is important because current vaccine approaches for immune therapy induce a response in just 1% to 3% of patients," says Dr. Ohashi, a senior scientist in signaling biology who holds a Canada Research Chair in Autoimmunity and Tumour Immunity. She is also a Professor, University of Toronto, in the Department of Medical Biophysics and Immunology. "

Dr. Tak Mak, co-author and CFIBCR director, says: "The promise of using the body's own defenses to fight cancer is enormous. The day is coming when immunotherapy may help spare cancer patients the toxic side effects of traditional therapies and greatly improve their quality of life while treating the disease. This is why we are planning to expand our immunotherapy research program at PMH." Dr. Mak is also a Professor, University of Toronto, in the Department of Medical Biophysics and Immunology.

This research was also financially supported by grants and fellowships from the Ca
'/>"/>

Contact: Jane Finlayson
jane.finlayson@uhn.on.ca
416-946-2846
University Health Network
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Scienceroll.com on Community Sites for Doctors and Scientists
2. Advancements in Integrative Medicine Research to Be Evaluated by Scientists From Leading International Academic Health Centers
3. Scientists From 25 Countries Sequence Cow Genome
4. Scientists Find New Way to Create Stem Cells
5. Reminder: Top Physician-Scientists Discuss State of Cancer Research at Damon Runyon Cancer Research Foundation Symposium
6. Keeping slim is good for the planet, say scientists
7. VirtualScopics Scientists to Present at International Society for Magnetic Resonance in Medicine 17th Scientific Meeting and Exhibition
8. Scientists Spot Stroke Genes
9. OHSU scientists partner with others to form center aimed at combating infectious diseases
10. BIDMC scientists receive creativity awards from Prostate Cancer Foundation
11. Scientists discover way to jumpstart bones healing process
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Gabe’s Chemo Duck Program is pleased to announce the release ... for kids with cancer. The Chemo Duck App, available on iTunes ... enjoyable games to help children of all ages living with cancer ... keep kids entertained, educated and at ease while waiting for clinic ...
(Date:1/22/2015)... 23, 2015 Angelweddingdress is a famous wedding ... its customers to follow it on Facebook, Twitter, and Pinterest. ... Day gift. Angelweddingdress draws a lottery every week. , Moreover, ... Feb. 28, 2015. Click Angelweddingdress homepage for more ...
(Date:1/22/2015)... Juvent Sports ( http://www.juventsports.com ) and ... Merchandise Show to bestow a Juvent Sports Achievement award ... Arlene McKitrick. The award commemorated and congratulated McKitrick for ... She won her first amateur tournament in 1979 and ...
(Date:1/22/2015)... 22, 2015 For over 20 years, Dr. David ... and Vista area has treated just about every type of ... circumstances. And for those same twenty-plus years, the team at ... those injuries with the best possible doctor. With the ...
(Date:1/22/2015)... 2015 Yesterday, Senator Holly Mitchell ... Kristin Olsen (R-Modesto) were honored by the California ... biotechnology, biomedical science, medical device and pharmaceutical innovation ... the “2014 Life Sciences Champion” award from CHI ...
Breaking Medicine News(10 mins):Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3
... LUCAS, Baja California Sur, Mexico, Feb. 4 The,7,000 ... will debut,on February 25, 2008 at Casa Dorada Los ... and Western spa philosophies, the Spa,s,signature services include a ... in a rhythmic massage that releases tonal,vibrations for physical ...
... Management Team (ASX: PGL; Nasdaq: PGLA) will be,conducting an ... time) and Monday 4 February at 5:00pm US EST., ... the Cellgate, Inc.,acquisition and will be available to answer ... the relevant presentation at: http://www.progen-pharma.com , Please ...
... to piece together the intricate series of interactions that ... determined the shape and structure of a binding site ... , In the Feb. 1 issue of Journal ... Qian Niu describe a region on the surface of ...
... Milestone Scientific,Inc. (OTC Bulletin Board: MLSS), the ... Scott Mahnken has joined the,Company,s leadership team as ... a wide range of strategic marketing and,communications initiatives ... sales growth, Mahnken will report directly to Bob ...
... half a million women around the world, including an ... planning methods developed by Georgetown University Medical Centers Institute ... of others use CycleBeads a visual aid developed by ... plan or prevent pregnancy. , Now CycleBeads are ...
... Respected Dermatologist says ,I am revolted by it;, ... WASHINGTON, Feb. 4 A group of,dermatologists, including ... Academy of Dermatopathology in New York City, has ... Recognition" program a,"shocking conflict of interest." The AAD ...
Cached Medicine News:Health News:East Meets West at Cabo San Lucas' New Saltwater Spa, Opening February 2Health News:Progen Investor Teleconference Dial In Details 2Health News:Breaking down Huntington's disease one protein at a time 2Health News:Milestone Scientific Appoints Dental Industry Veteran Scott Mahnken as New Director of Marketing 2Health News:Milestone Scientific Appoints Dental Industry Veteran Scott Mahnken as New Director of Marketing 3Health News:CycleBeads help women manage their fertility 2Health News:American Academy of Dermatology Caught in Pay-for-Play Scandal 2
(Date:1/23/2015)... DUBLIN , Jan. 23, 2015 Research and Markets ... "Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, ... offering. Video communication has been the topic of ... the United States and the Soviet Russia. ...
(Date:1/23/2015)... BETHESDA, Md. , Jan. 23, 2015  Northwest Biotherapeutics, Inc. ... developing DCVax® personalized immune therapies for operable and inoperable solid ... will present at the 7 th Annual Phacilitate Immunotherapy ... NW Bio,s presentation at Phacilitate will take place on January ...
(Date:1/23/2015)... all-time hits leader, is the new spokesperson for the topical ... announced. "Pete,s a Hall of Famer in our ... with Myoflex," said Ducere Pharma Chief Executive Officer Chris ... across all generations. The passion and intensity that Pete brought ...
Breaking Medicine Technology:Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3Pete Rose bets on Myoflex to relieve aches and pains 2
... easily accessible medicines have the potential to be misused ... teens and young adults . Actress and parent ... Americans to take personal responsibility for properly storing and ... falling into the wrong hands. Hicks will be taking ...
... 10, 2011 Experts call for patients to ... New research released today to mark European Week Against ... levels of pain across Europe are not being adequately assessed. ... http://multivu.prnewswire.com/mnr/prne/mundipharma/52140/ More than half ...
Cached Medicine Technology:"7th Heaven" and "Game Time" Star Catherine Hicks to Appear at the National Community Pharmacists Association's Convention October 10, 2011 in Nashville for Education Effort to Help Prevent Prescription Medication Abuse 2"7th Heaven" and "Game Time" Star Catherine Hicks to Appear at the National Community Pharmacists Association's Convention October 10, 2011 in Nashville for Education Effort to Help Prevent Prescription Medication Abuse 3New Research Shows Chronic Pain is not Being Adequately Measured[1] 2New Research Shows Chronic Pain is not Being Adequately Measured[1] 3New Research Shows Chronic Pain is not Being Adequately Measured[1] 4New Research Shows Chronic Pain is not Being Adequately Measured[1] 5
... CT is a completely automated, ... performing clotting assays in random ... method of sample management offers ... of STAT samples without the ...
... Alpha Fetoprotein (AFP) is a 68 kDa protein, ... the fetal liver and yolk sac [1]. ... weeks gestation, and production rates reach 19-26 g/min ... and estimates of total fetal AFP continue to ...
... movement is critical to ... Thats why this scale ... to do just that. ... technology, these wheelchair scales ...
... Inovise Medicals AUDICOR is the ... medical professionals worldwide quickly rule-in cardiac ... coronary syndrome, and other high-risk cardiac ... the existing workflow, AUDICOR products enable ...
Medicine Products: