Navigation Links
Scientists discover genetic variant associated with prostate cancer in African Americans
Date:10/31/2007

Wednesday, October 31, 2007 Today researchers report a newly identified genetic variation that is linked to higher incidence of prostate cancer in African American men. This study, which emphasizes the importance of characterizing genetic markers associated with prostate cancer in high-risk populations, is published online in Genome Research (www.genome.org).

Prostate cancer is the second leading cause of cancer death in men and, according to the American Cancer Society, will claim the lives of more than 27,000 men in the United States this year. Among different populations, prostate cancer exhibits significant variation in incidence rates, with African American men exhibiting the highest rate worldwide.

Recent studies investigating genetic variations associated with susceptibility to prostate cancer have implicated a specific region of chromosome 8 as harboring potential markers for the disease. In the study published today, the research groups lead by Dr. Rick Kittles of the University of Chicago and Dr. John Carpten of the Translational Genomics Research Institute further analyzed the 8q24 region of chromosome 8 by comparing the genotypes of 490 African American men diagnosed with prostate cancer and 567 control subjects. This study took advantage of differences in genetic ancestry among the African American men in order to replicate and further localize a risk locus for prostate cancer, says Kittles.

Using this information, the researchers characterized new genetic markers which were significantly associated with prostate cancer. Since the prevalence of prostate cancer is almost two-fold higher among African Americans compared to European Americans, the use of ancestry informative markers for association with prostate cancer is quite powerful. We identified a novel prostate cancer risk locus that maps within a gene region on 8q24, Kittles says. This region contains an int
'/>"/>

Contact: Peggy Calicchia
calicchi@cshl.edu
516-422-4012
Cold Spring Harbor Laboratory
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Nobel Prize for Medicine shared by Three scientists
2. Scientists plan human cloning clinic in the United States
3. Scientists crack mechanism of Leptin-Obesity Hormone
4. Scientists use plant hormones to fight cancer
5. American scientists alter gene makeup of babies
6. Expose on eating disorders!! Scientists trace “brain’s eating control center pathway”
7. Scientists found ancient Human Germ Killer
8. Scientists locate key hormone involved in appetite control
9. Scientists open the book of life
10. Electronic nose by Italian scientists
11. Scientists review SARS

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/8/2009)...ealth Care Reform Bill ,, Critical legislatio...all Americans ,, BALTIMORE, Nov. 7 /PRNewswire...es House of Representatives passed critical health...icare for seniors and end discrimination by insura...t of affordable health coverage. ,, The Afforda...
(Date:11/7/2009)...e-USNewswire/ -- Speaker Nancy Pelosi spoke on th...ffordable Health Care for America Act. The House ... are the Speaker,s remarks. ,, "Madam Speaker,...our nation and for American families. For nearly ...ilosophy -- as far back as Teddy Roosevelt -- have...
(Date:11/7/2009)...d A. Cook (GA), Louis J. Goodman (TX), Palmer P. J...CAGO, Nov. 7 The Americ...medical society executive leaders with achievement...and ideals of the medical profession. The awards w...ng meeting in Houston. ,, (Logo: http://www....
(Date:11/7/2009)...SNewswire/ -- With the final House vote on healthc...ing the entire bill hostage to further their antia...o far beyond the status quo restrictions on aborti...ll. In an outrageous amendment, which is expected...ce Democrats are demanding explicit and unequivoca...
(Date:11/7/2009)...SNewswire/ -- Speaker Nancy Pelosi and Democratic ...ollowing a Democratic Whip meeting with President ...eaker,s opening remarks: ,, "Thank you very mu... to receive the President of the United States on ...ote and making progress for the American people. ...
Breaking Medicine News(10 mins):Health News:AARP Maryland Key Vote News Alert 2Health News:AARP Maryland Key Vote News Alert 3Health News:Pelosi: Health Legislation Founded on Key Principles for a Healthier America: Innovation, Competition and Prevention 2Health News:Pelosi: Health Legislation Founded on Key Principles for a Healthier America: Innovation, Competition and Prevention 3Health News:Pelosi: Health Legislation Founded on Key Principles for a Healthier America: Innovation, Competition and Prevention 4Health News:AMA Honors Medical Society Executives 2Health News:Pelosi Remarks Following House Democrats' Meeting with President Obama 2
...Scrip,s new Pharmaceutical Company,League Tables, ...ace behind,Johnson &Johnson (J&J) in the list of c...ss divisions. Only 43% of J&J,s revenue comes fro...gh operating conditions in 2006 -,caused by patent...
...espite widespread belief among cancer patients and...relieve nausea caused by cancer treatment, new res...he study, presented today (Wednesday) at the Europ...ctive acupuncture or a sham treatment that involve...
...h metastatic breast cancer who have also endured p...ncer recur nearly twice as fast as other women, ac...edical Center scientist. , The small, retrospec...pared with women who have more peaceful lives, who...
... Quality and Convenience Close to Home and the ..., Sept. 26 MinuteClinic,( http://www.minuteclinic...-,based health care in the United States, has open...the area by the end of,the year. MinuteClinic hea...
.... 26 Milestone,Scientific, Inc. (OTC Bulletin Boa...tion technologies, today announced that senior off...g EdgeWater Research Fall 2007,Small/Micro Cap Con...EN: Wednesday, October 10, 2007 at 8:50 AM MDT, ...
...er danger, but doses must be very high , ,... doses of caffeine and acetaminophen (such as Tyle...researchers warn. , This combo produces a byproduc... while taking acetaminophen, the experts added, bu...
Other Medicine News:Health News:Johnson & Johnson Tops Annual Pharmaceutical Company Rankings in a New Report From Industry-Leading Publication Scrip 2Health News:Acupuncture does not reduce radiotherapy-induced nausea, but patients believe it does 2Health News:Got stress? It could impact breast cancer recurrence 2Health News:An Innovation in Health Care Opens at CVS/pharmacy Stores in Pittsburgh 2Health News:An Innovation in Health Care Opens at CVS/pharmacy Stores in Pittsburgh 3Health News:An Innovation in Health Care Opens at CVS/pharmacy Stores in Pittsburgh 4Health News:Milestone Scientific to Present at the Edgewater Research Investor Conference 2Health News:Caffeine Plus Acetaminophen Toxic for Some 2
(Date:11/6/2009)...wire-FirstCall/ -- Boston Scientific Corporation (...n agreement in principle with the U.S. Department ...ued by its Guidant subsidiary in 2005. The allege...on Scientific,s 2006 acquisition of Guidant. ,,...estigation by the U.S. Attorney,s Office in Minnea...
(Date:11/6/2009)...FirstCall/ -- Keryx Biopharmaceuticals, Inc. (Nasd..., November 10, 2009 at 8:30 a.m. EST to discuss th...s outlook for the remainder of 2009. Ron Bentsur,... the call. Keryx will announce its financial resu...d prior to the call. ,, In order to participate...
(Date:11/6/2009)...irstCall/ -- Caraco Pharmaceutical Laboratories, L...ethamine ophthalmic solution, 0.5% following a fin...on (FDA) for Sun Pharma,s Abbreviated New Drug App... solution on the first day following patent expira...y equivalent to Acular® Ophthalmic Solution, ...
Breaking Medicine Technology:Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 2Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 3Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 4Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 5Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 6Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 7Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 8Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 9Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 10Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 11Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 12Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 13Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 14Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 15Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 16Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 17Keryx Biopharmaceuticals, Inc. to Hold Conference Call on Third Quarter 2009 Financial Results on Tuesday, November 10, 2009 at 8:30 a.m. EST 2Caraco Pharmaceutical Laboratories, Ltd. Markets Generic Acular(R) Opthalmic Solution 2Inc 500 Ranks Charlesson as One of Americas Fastest Growing Private Companies 54831 1Inc 500 Ranks Charlesson as One of Americas Fastest Growing Private Companies 54831 2Sonic Innovations Awarded Contract From U S Veterans Administration 54829 1Sonic Innovations Awarded Contract From U S Veterans Administration 54829 2Sonic Innovations Awarded Contract From U S Veterans Administration 54829 3Bayard Advertising Appointed by Hospital Corporation of America 28HCA 29 West Florida Division for Recruitment Advertising and Employment Branding 54828 1Bayard Advertising Appointed by Hospital Corporation of America 28HCA 29 West Florida Division for Recruitment Advertising and Employment Branding 54828 2
... 16 SuperGen Inc.,(Nasdaq: SUPG ), a pharmaceuti...lopment and commercialization of therapies for sol...nounced as part of a series of,presentations at th...fied a,lead PIM kinase inhibitor, SGI-1776, that c...ia (AML) xenograft models (Abstract No. 4083)., I...
...g Forward with a planned IND Filing for Novavax,s ...ate, ROCKVILLE, Md., April 16 Novavax, Inc.,(Nas...ive results from an,immunogenicity study in ferret... influenza vaccine candidate. These findings will ...onal new drug ("IND") application to,support initi...
Other Medicine Technology:SuperGen Identifies Lead PIM Kinase Inhibitor, SGI-1776, That Causes Tumor Regression in AML Xenograft Models 2Novavax Reports Positive Results from Preclinical Studies of its VLP-based Trivalent Seasonal Influenza Vaccine Candidate 2Novavax Reports Positive Results from Preclinical Studies of its VLP-based Trivalent Seasonal Influenza Vaccine Candidate 3
...es is a national reference laboratory and a worldw...evelopment. ARUP offers an extensive test menu of ...l and anatomic pathology. Owned by the University ...han half of the nation's university teaching hospi...
...es is a national reference laboratory and a worldw...evelopment. ARUP offers an extensive test menu of ...l and anatomic pathology. Owned by the University ...han half of the nation's university teaching hospi...
...es is a national reference laboratory and a worldw...evelopment. ARUP offers an extensive test menu of ...l and anatomic pathology. Owned by the University ...han half of the nation's university teaching hospi...
...es is a national reference laboratory and a worldw...evelopment. ARUP offers an extensive test menu of ...l and anatomic pathology. Owned by the University ...han half of the nation's university teaching hospi...
Medicine Products: