Navigation Links
Scientists develop 'designer protein,' opening new door in cancer research
Date:8/3/2010

WINSTON-SALEM, N.C. Tuesday, Aug. 3, 2010 A major breakthrough in how to target and destroy the most malignant and aggressive brain cancer cells has been made by researchers at Wake Forest University Baptist Medical Center.

Scientists have identified a way to target and destroy Glioblastoma multiforme (GBM) cells without harming healthy cells.

The finding allows for new possibilities in cancer research previously not known to be readily feasible.

"Treatment of patients with Glioblastoma multiforme is still a major challenge, as GBM is extremely difficult to manage," said Waldemar Debinski, M.D., Ph.D., director of the Brain Tumor Center of Excellence at Wake Forest Baptist. "Over the last 30 to 40 years, with all the cancer research efforts out there, we have only been able to extend the survival rate in these patients by about one month per decade of research. People who have this kind of cancer survive for an average of 14.5 months after diagnosis, although some with this form of cancer can live longer than that average. I don't think anyone would label this satisfactory progress."

Debinski, a professor of neurosurgery and senior investigator on the study, and colleagues have thus focused their efforts on finding a way to treat these tumors something potentially less toxic and invasive than surgery, radiation and chemotherapy in the form of molecular targeting.

Their latest achievement, recently featured on the cover of the journal Genes and Cancer, is the result of years of research funded by the National Cancer Institute.

Almost 20 years ago, Debinski and colleagues developed what Debinski has dubbed a "designer protein," a single-chain protein that is able to seek out and make its way into specific cells, such as cancer cells. The challenge, and most recent focus of the researchers' work, has been finding a way to program that protein, once inside the targeted cell, to locate and accumul
'/>"/>

Contact: Jessica Guenzel
jguenzel@wfubmc.edu
336-716-3487
Wake Forest University Baptist Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Scientists Pinpoint Area of Brain That Fears Losing Money
2. Scientists Discover How HIV Is Transmitted Between Men
3. Prevention Is Key Research Goal for Premature Babies, Scientists Say
4. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
5. Scientists find donut-shaped structure of enzyme involved in energy metabolism
6. Neuroscientists reveal new links that regulate brain electrical activity
7. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. Scientists Spot Genetic Fingerprints of Individual Cancers
10. Scientists Unravel Mysteries of Intelligence
11. MSU scientists develop more effective method of predicting lead-poisoning risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... The Alaska Center for Dentistry ... dentist Dr. Jonathan Oudin, DDS, who will begin working ... Barrow, Alaska, for three years. According to Teresa Wallace, ... Oudin to help take on new patients. , "This ... growing and serving the greater Anchorage metro community," Wallace ...
(Date:7/31/2014)... ROCHESTER, Minn. Implementation of an algorithm aimed ... the utilization of computed tomography (CT) scans, without ... have found. The study was recently published in ... is the most common cause of acute abdominal ... becomes inflamed and filled with pus. CT scans ...
(Date:7/31/2014)... (PRWEB) July 31, 2014 Setting goals for ... on blogs on successful tips to weight loss. Fitness on ... for over 8 years, and has worked with 6000 customers ... “We have had the chance to monitor why customers start ... exercising, how long they stick to their program, whether or ...
(Date:7/31/2014)... (PRWEB) July 31, 2014 Women in ... take charge of their financial future. The Independent ... has opened registration for 6 upcoming Los Angeles area ... for women, and with input from Kim Kiyosaki, a ... It’s Rising Time) who is passionate about women’s financial ...
(Date:7/31/2014)... NV (PRWEB) July 31, 2014 ... helping independent pharmacies enhance patient care by kicking ... and medication adherence. The first of many education ... opening of ThoughtSpot 2014, Good Neighbor Pharmacy and ... Medicare and Medicaid Services (CMS) Star Measures were ...
Breaking Medicine News(10 mins):Health News:Dr. Jonathan Oudin to Join Alaska Center for Dentistry at Wasilla Location 2Health News:Fitness on the Go's Rewards Program Helps Clients Reach Their Goals 2Health News:The Independent Woman to Offer Financial Workshops in the Los Angeles Area - Developed by Women for Women 2Health News:Good Neighbor Pharmacy Reinforces Commitment to Helping Enhance Patient Care 2Health News:Good Neighbor Pharmacy Reinforces Commitment to Helping Enhance Patient Care 3
... August 2, 2011 Engaging in physical activity after ... of survival. In a study published in the September ... , researchers from the Israel Study Group on First ... who lived in low socioeconomic status (SES) neighborhoods engaged ...
... 29, 2011) − In a recent study published in ... University of Kentucky College of Nursing and Mark Pyles, ... at the College of Charleston, found smoke-free legislation does ... urban communities. This is true regardless of whether the ...
... , MONDAY, Aug. 1 (HealthDay News) -- Teens are much ... or go to school in neighborhoods with many fast food ... finds. Researchers compared 2007 data on junk food consumption ... junk food outlets, such as fast food restaurants, convenience stores, ...
... Reporter , MONDAY, Aug. 1 (HealthDay News) -- Take the stairs ... tag with your kids at the park. New research shows ... 2.5 hours, of moderate activity a week -- can reduce the ... did more -- about 300 minutes a week, or five hours ...
... in a form of T cell leukemia, according to a ... of Experimental Medicine ( www.jem.org ). Approximately half ... carry genetic mutations in a cellular signaling pathway called Notch, ... by Andrew Weng and colleagues at the British Columbia Cancer ...
... Reston, Va. (August 1, 2011) Two new studies ... of Nuclear Medicine (JNM) provide insight into the ... types of dementia and to identify pharmaceuticals to slow ... Aging (NIA) and the Alzheimer,s Association guidelines for detecting ...
Cached Medicine News:Health News:Heart attack survivors from poorer neighborhoods get less exercise 2Health News:Study finds smoke-free laws don't impact rural or urban economies 2Health News:With Junk Food Stores Nearby, Teens May Eat More of It 2Health News:Even a Little Exercise Helps the Heart, Study Finds 2Health News:Even a Little Exercise Helps the Heart, Study Finds 3Health News:New JNM research supports upcoming Alzheimer's disease guidelines 2
(Date:7/31/2014)... , July 31, 2014 Touro University ... has been selected as the recipient of a $150,000 ... will allow the University to increase research and classroom ... creating state-of-the-art technology for the study of health sciences, ... the diverse needs and interests of our students," said ...
(Date:7/31/2014)... SAN FRANCISCO , July 31, 2014 /PRNewswire/ ... ) and Aspira Scientific ( Milpitas, California ... joint venture to develop and commercialize new fluorination ... biologically active molecules has benefited from the use ... metabolism, and combine lipophilicity with polarity to improve ...
(Date:7/31/2014)... ANTWERP, Belgium and LONDON , July ... Organization (CRO) and services provider for the medical industries, announced today ... The United Kingdom has one ... valued at USD 8.9 billion in 2012 and it is projected ... was estimated at USD 234 billion in 2012, equal to 9.5% ...
Breaking Medicine Technology:Touro University California Garners Grant From Long Foundation 2Catylix, Inc. and Aspira Scientific Announce Joint Venture to Commercialize New Fluorination Technologies 2genae Opens Offices in London 2
... 22, 2011 MedVantx, Inc., today announced the deployment ... medication and adherence reporting engine across its ... in the Company,s integrated program of initial free medication ... program utilizes the Company,s proprietary automated ATM like sample ...
... NEW YORK, Nov. 22, 2011 ... research report is available in its ... - Global Pipeline Analysis, Competitive Landscape ... http://www.reportlinker.com/p0685953/MRI-Systems---Global-Pipeline-Analysis-Competitive-Landscape-and-Market-Forecasts-to-2017.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Imaging ...
Cached Medicine Technology:MedVantx Launches Patient Profile™, A Proprietary Closed-Loop Pharmaceutical Adherence Management Program for Medical Home, Accountable Care and Population Health Management 2MedVantx Launches Patient Profile™, A Proprietary Closed-Loop Pharmaceutical Adherence Management Program for Medical Home, Accountable Care and Population Health Management 3MRI Systems - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 2MRI Systems - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 3MRI Systems - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 4MRI Systems - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 5MRI Systems - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 6MRI Systems - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 7MRI Systems - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 8MRI Systems - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 9MRI Systems - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 10MRI Systems - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 11MRI Systems - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 12