Navigation Links
Scientists develop 'designer protein,' opening new door in cancer research
Date:8/3/2010

WINSTON-SALEM, N.C. Tuesday, Aug. 3, 2010 A major breakthrough in how to target and destroy the most malignant and aggressive brain cancer cells has been made by researchers at Wake Forest University Baptist Medical Center.

Scientists have identified a way to target and destroy Glioblastoma multiforme (GBM) cells without harming healthy cells.

The finding allows for new possibilities in cancer research previously not known to be readily feasible.

"Treatment of patients with Glioblastoma multiforme is still a major challenge, as GBM is extremely difficult to manage," said Waldemar Debinski, M.D., Ph.D., director of the Brain Tumor Center of Excellence at Wake Forest Baptist. "Over the last 30 to 40 years, with all the cancer research efforts out there, we have only been able to extend the survival rate in these patients by about one month per decade of research. People who have this kind of cancer survive for an average of 14.5 months after diagnosis, although some with this form of cancer can live longer than that average. I don't think anyone would label this satisfactory progress."

Debinski, a professor of neurosurgery and senior investigator on the study, and colleagues have thus focused their efforts on finding a way to treat these tumors something potentially less toxic and invasive than surgery, radiation and chemotherapy in the form of molecular targeting.

Their latest achievement, recently featured on the cover of the journal Genes and Cancer, is the result of years of research funded by the National Cancer Institute.

Almost 20 years ago, Debinski and colleagues developed what Debinski has dubbed a "designer protein," a single-chain protein that is able to seek out and make its way into specific cells, such as cancer cells. The challenge, and most recent focus of the researchers' work, has been finding a way to program that protein, once inside the targeted cell, to locate and accumul
'/>"/>

Contact: Jessica Guenzel
jguenzel@wfubmc.edu
336-716-3487
Wake Forest University Baptist Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Scientists Pinpoint Area of Brain That Fears Losing Money
2. Scientists Discover How HIV Is Transmitted Between Men
3. Prevention Is Key Research Goal for Premature Babies, Scientists Say
4. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
5. Scientists find donut-shaped structure of enzyme involved in energy metabolism
6. Neuroscientists reveal new links that regulate brain electrical activity
7. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. Scientists Spot Genetic Fingerprints of Individual Cancers
10. Scientists Unravel Mysteries of Intelligence
11. MSU scientists develop more effective method of predicting lead-poisoning risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/27/2015)... OR (PRWEB) April 27, 2015 Climate ... Their accuracy depends on the number of variables used ... Recently, two noted scientists, water researcher Gerald Pollack, PhD, ... Kleyne Hour™ Power of Water® radio show, noted three ... simulations. , None of these individuals dispute that ...
(Date:4/27/2015)... 2015 The WeedLife Network has ... problem that has been troubling cannabis businesses with ... by announcing the launch of WeedLIVE, the first-ever ... , Officially launched today, WeedLIVE.com is designed specifically ... index only marijuana-related business websites. , WeedLIVE deals ...
(Date:4/27/2015)... 2015 The Radiology Business Management ... with applied business information and intelligence, is proud to ... email newsletter for its more than 2,000 members. , ... legislative news sources in that it is exclusively devoted ... of radiology. The newsletter is produced in cooperation with ...
(Date:4/27/2015)... IL (PRWEB) April 27, 2015 Pure ... launch of its brand new website design at ... list of the company’s product catalog, both featured and ... Natural blog ( http://www.purennatural.com/blog/ ). , Pure n Natural ... and satisfying shopping experience. The website is neatly organized ...
(Date:4/27/2015)... Portland, Ore. (PRWEB) April 27, 2015 ... Ben Albert has joined its team as ... division, an area focused on investing in and building ... care system. In his new role, Albert will be ... transforming health care so that it is both economically ...
Breaking Medicine News(10 mins):Health News:Global warming: Computer weather models flawed report Climatologist, Water Researcher on Sharon Kleyne Hour™ radio show 2Health News:Global warming: Computer weather models flawed report Climatologist, Water Researcher on Sharon Kleyne Hour™ radio show 3Health News:The WeedLife Network debuts its ground-breaking WeedLIVE cannabis industry search engine 2Health News:The WeedLife Network debuts its ground-breaking WeedLIVE cannabis industry search engine 3Health News:Radiology Business Management Association Launches Weekly Legislative and Policy Newsletter 2Health News:Pure n Natural Systems, Inc. Launches New Website Design 2Health News:Pure n Natural Systems, Inc. Launches New Website Design 3Health News:Cambia Welcomes Ben Albert as Operating Partner 2Health News:Cambia Welcomes Ben Albert as Operating Partner 3
... BASKING RIDGE, N.J., Sept. 9 Regado Biosciences, a ... aptamers with active control agents, announced that on September ... Phase 2b, randomized, partially-blinded, multi-center, active-controlled, dose-ranging study of ... was achieved. REG1 comprises the selective factor IXa ...
... STOCKHOLM, September 9 Karolinska ... company that will commercialize its,dermatology and wound healing opportunities ... transferred all of its,holdings from its five dermatology and ... new company. , "This is ...
... 9 CRGT, a leading provider of Information Technology (IT) ... premier sponsor of the Teardrops to Rainbows 7th annual Golf ... Golf & Hunt Club in Leesburg, Virginia. The tournament ... Teardrops to Rainbows is a non-profit organization that provides support, ...
... , ATLANTA, Sept 9 The ... for improving health and appearance are still available. , ... Feet" program offers a top-of-the-line skin rejuvenation and repair procedure ... Dr. David R. Fern, FACS. Dr. Fern and the Vein & ...
... , Optometry & Vision Development, Volume 40, Number 3, 2009 ... What is its cause? How does it affect brain anatomy, electrophysiology, visual ... these patients? How can optometrists as health care providers be in the ... The latest issue of Optometry & Vision Development ...
... , SAN DIEGO, Sept. 9 ... announced today that it is providing a co-pay assistance savings ... The savings program is available through physicians enrolled in ... responsible for the first $50 of their LOTRONEX prescription co-pay, ...
Cached Medicine News:Health News:Regado Biosciences Announces First Patient Enrolled in RADAR (Phase 2b) Study of REG1 Anticoagulation System 2Health News:Regado Biosciences Announces First Patient Enrolled in RADAR (Phase 2b) Study of REG1 Anticoagulation System 3Health News:Karolinska Development Introduces New Concept for Development of its Dermatology and Wound Healing Portfolio 2Health News:CRGT Sponsors Teardrops to Rainbows Golf Tournament 2Health News:'Cash For Crow's Feet' Program Offers Effective - and Affordable - Laser Skin Treatments 2Health News:Special Autism Issue Published by the College of Optometrists in Vision Development 2Health News:Special Autism Issue Published by the College of Optometrists in Vision Development 3Health News:Prometheus Announces Co-Pay Assistance Savings Program for LOTRONEX(R) (alosteron HCl) Tablets 2Health News:Prometheus Announces Co-Pay Assistance Savings Program for LOTRONEX(R) (alosteron HCl) Tablets 3Health News:Prometheus Announces Co-Pay Assistance Savings Program for LOTRONEX(R) (alosteron HCl) Tablets 4
(Date:4/24/2015)... 24, 2015  Bayer Corporation hosted its annual "Take Your ... Bayer HealthCare US headquarters.  This is Bayer,s second "Take Your ... Whippany campus, and Thursday,s event welcomed 230 children ... at work. Fortunately, for the kids, this was ... whose mission is "Science For A Better Life," Bayer made ...
(Date:4/24/2015)... , April 24, 2015 In today,s ... employee groups around the world to access diverse ... hours. While there are many areas to misstep ... examine which best practices are necessary and beneficial ... According to research by benchmarking firm, ...
(Date:4/24/2015)... and Markets ( http://www.researchandmarkets.com/research/pmbmv2/global_biobanking ) has announced ... report to their offering. The analysts ... CAGR of 7.07% over the period 2014-2019 ... segments: Equipment and Consumables. This report covers the present ... market for the period 2015-2019. ...
Breaking Medicine Technology:Bayer Hosts "Take Your Child to Work Day" 2Bayer Hosts "Take Your Child to Work Day" 3Bayer Hosts "Take Your Child to Work Day" 4Work Around the Clock: Building Effective Global Capabilities 2Global Biobanking Market Report 2015-2019 - Increase in Strategic Collaborations with Beckman Coulter, Tecan & Thermo Fischer Scientific Dominating 2
... May 2, 2011 NewCardio, Inc., (OTC BB: NWCI) a ... prestigious NYC Bright Lights Conference at the Le Parker Meridien ... of its kind with an exclusive focus on publicly traded ... will present on May 10, 2011 at 9 a.m. ET. ...
... Fla., May 2, 2011 The Unilens Vision Inc. ... of Directors today declared a quarterly cash dividend of $0.045 per ... record at the close of business on May 13, 2011. ... Specialty Contact Lens Company" Established in 1989, Unilens ...
Cached Medicine Technology:NewCardio to Showcase Cardiac Diagnostic Technology at MDB Capital's Bright Lights Conference in New York City on May 10, 2011 2NewCardio to Showcase Cardiac Diagnostic Technology at MDB Capital's Bright Lights Conference in New York City on May 10, 2011 3NewCardio to Showcase Cardiac Diagnostic Technology at MDB Capital's Bright Lights Conference in New York City on May 10, 2011 4Unilens Vision Inc. Declares Quarterly Cash Dividend of $0.045 Per Share 2
Lightweight Pneumatic Conserver., ,NOTE: All models passed the ASTM PS 127-00 regulator ignition safety test....
Lightweight Pneumatic Conserver., ,NOTE: All models passed the ASTM PS 127-00 regulator ignition safety test....
... ,Offers an average 5:1 increase in usage ... use of a standard cannula. , ,The ... offers ambulatory oxygen patients a superior alternative to ... 2-year warranty. , ...
Redesigning the World's Oxygen Therapy One Device at a Time. , ,Everything you like about our OXYMATIC 400 Series conservers, only better!...
Medicine Products: