Navigation Links
Scientists develop 'designer protein,' opening new door in cancer research
Date:8/3/2010

WINSTON-SALEM, N.C. Tuesday, Aug. 3, 2010 A major breakthrough in how to target and destroy the most malignant and aggressive brain cancer cells has been made by researchers at Wake Forest University Baptist Medical Center.

Scientists have identified a way to target and destroy Glioblastoma multiforme (GBM) cells without harming healthy cells.

The finding allows for new possibilities in cancer research previously not known to be readily feasible.

"Treatment of patients with Glioblastoma multiforme is still a major challenge, as GBM is extremely difficult to manage," said Waldemar Debinski, M.D., Ph.D., director of the Brain Tumor Center of Excellence at Wake Forest Baptist. "Over the last 30 to 40 years, with all the cancer research efforts out there, we have only been able to extend the survival rate in these patients by about one month per decade of research. People who have this kind of cancer survive for an average of 14.5 months after diagnosis, although some with this form of cancer can live longer than that average. I don't think anyone would label this satisfactory progress."

Debinski, a professor of neurosurgery and senior investigator on the study, and colleagues have thus focused their efforts on finding a way to treat these tumors something potentially less toxic and invasive than surgery, radiation and chemotherapy in the form of molecular targeting.

Their latest achievement, recently featured on the cover of the journal Genes and Cancer, is the result of years of research funded by the National Cancer Institute.

Almost 20 years ago, Debinski and colleagues developed what Debinski has dubbed a "designer protein," a single-chain protein that is able to seek out and make its way into specific cells, such as cancer cells. The challenge, and most recent focus of the researchers' work, has been finding a way to program that protein, once inside the targeted cell, to locate and accumul
'/>"/>

Contact: Jessica Guenzel
jguenzel@wfubmc.edu
336-716-3487
Wake Forest University Baptist Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Scientists Pinpoint Area of Brain That Fears Losing Money
2. Scientists Discover How HIV Is Transmitted Between Men
3. Prevention Is Key Research Goal for Premature Babies, Scientists Say
4. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
5. Scientists find donut-shaped structure of enzyme involved in energy metabolism
6. Neuroscientists reveal new links that regulate brain electrical activity
7. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. Scientists Spot Genetic Fingerprints of Individual Cancers
10. Scientists Unravel Mysteries of Intelligence
11. MSU scientists develop more effective method of predicting lead-poisoning risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... 2014 JZ Fitness, an independently operated ... wellness programming, authorship, international lecturing and community wellness, created ... the release of the JZ Fitness nutrition app, available ... coaching thousands of individuals on nutrition, Jenn Zerling (“JZ”) ... not require calorie counting or cumbersome food logging. ...
(Date:10/20/2014)... 20, 2014 AttorneyOne.com, a recognized authority on ... from the FDA on Sit and Slim II . ... to purchase or use Sit and Slim II because it ... is promoted as weight loss product on various websites and ... market in 2010 for safety reasons, can significantly increase blood ...
(Date:10/20/2014)... Succeed is proud to announce that they ranked ... the Every Body Walk! campaign by Kaiser Permanente. ... encourages workers to be more active outside of the workplace. ... at the end of September, was a friendly competition between ... Participating companies gave their staff pedometers and each day, ...
(Date:10/20/2014)... 2014 Final Cut Pro X Plugin developers ... Citrus theme for FCPX filmmakers . , “Fun, cool, ... the Citrus theme” Says Christina Austin, CEO of Pixel Film ... professional.” , Citrus comes with all the tools needed for ... four transitions for added style, a title screen for an ...
(Date:10/20/2014)... Punzoné , the first line of ... a lot to celebrate this month. October marks Italian Heritage ... and contributions of Americans of Italian heritage and Italians in ... it shares its favorite Italian cocktails and encourages everyone to ... even if it is only in a glass. , ...
Breaking Medicine News(10 mins):Health News:JZ Fitness Nutrition App Launches on iTunes 2Health News:JZ Fitness Nutrition App Launches on iTunes 3Health News:FDA Advises Not to Use Sit and Slim II: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Succeed Management Solutions, LLC Competes in Walking Challenge and Achieves 12th Place in Portland 2Health News:Today Pixel Film Studios Announced the Release of the Citrus theme for Final Cut Pro X 2Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 2Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 3Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 4
... worldwide as the standard of care for a serious lung ... should not be used together to treat the disease, called ... rigorous independent study. The study, which will appear online ... to coincide with a presentation at the annual meeting ...
... Rosenfeld, M.D., M.P.H., of Seattle Children,s Hospital, and colleagues conducted ... rate of pulmonary exacerbations in children younger than 6 years ... recommended as therapy for patients 6 years or older with ... younger than 6 years. In the randomized trial, the ...
... obstructive sleep apnea (OSA) in children normalizes disturbances in ... according to a new study. "OSA is ... and executive function," said lead author Ann Halbower, MD, ... University of Colorado Denver. "Our study is the first ...
... Preliminary results from an ongoing, large-scale study by Yale ... naturally occurring substance produced in the brain and throughout ... known to process social information in children and adolescents ... Child Study Center research team that includes postdoctoral fellow ...
... News) -- Female athletes take longer to recover from ... have longer recovery times. The findings show that doctors ... into account when treating patients with concussions, said researchers ... from nearly 300 athletes in the United States who ...
... News) -- Older men have an increased risk of developing ... not know how to properly check themselves for signs of ... worrisome because nearly 132,000 new cases of melanoma will be ... which conducted the online poll. "This survey demonstrates that ...
Cached Medicine News:Health News:First, do no harm: Study finds danger in standard treatment for a serious lung disease 2Health News:First, do no harm: Study finds danger in standard treatment for a serious lung disease 3Health News:Treatment of childhood OSA reverses brain abnormalities 2Health News:Oxytocin improves brain function in children with autism 2Health News:Females, Young Athletes Take Longer to Get Over Concussions 2Health News:Melanoma a Big Threat to Older Men 2
(Date:10/17/2014)... 2014 UBM Medica US announces that ... and information resource for neurologists and other healthcare providers, features ... disease , with discussions of the latest developments in approaches ... have Parkinson disease , more than the total of those ... disease. Diagnosis can be difficult because there are no ...
(Date:10/17/2014)... DALLAS , October 17, 2014 /PRNewswire/ ... research report "Optical Imaging Market by Technique (Optical ... System, Imaging software) & by Application (Ophthalmology, Neurology, Oncology, ... by MarketsandMarkets, this report studies the Optical Imaging ... The market was valued at $917.1 million ...
(Date:10/17/2014)... -- Investor-Edge has initiated coverage on the ... ), NPS Pharmaceuticals Inc. (NASDAQ: NPSP ), ... Inc. (NASDAQ: MNTA ), and Catalyst Pharmaceutical ... companies can be accessed at: http://investor-edge.com/register . ... ended on a mixed note as the Dow Jones ...
Breaking Medicine Technology:Neurology Times Features Coverage of Parkinson and Alzheimer Disease 2Neurology Times Features Coverage of Parkinson and Alzheimer Disease 3Optical Imaging Market Worth $1,669.2 Million by 2019 2Optical Imaging Market Worth $1,669.2 Million by 2019 3Optical Imaging Market Worth $1,669.2 Million by 2019 4Biotech Equities Technical Briefing - Arena Pharma, NPS Pharma, XOMA, Momenta Pharma, and Catalyst Pharma Partners 2Biotech Equities Technical Briefing - Arena Pharma, NPS Pharma, XOMA, Momenta Pharma, and Catalyst Pharma Partners 3Biotech Equities Technical Briefing - Arena Pharma, NPS Pharma, XOMA, Momenta Pharma, and Catalyst Pharma Partners 4Biotech Equities Technical Briefing - Arena Pharma, NPS Pharma, XOMA, Momenta Pharma, and Catalyst Pharma Partners 5
... PHILADELPHIA, Sept. 9 Compliance Implementation Services (CIS), ... it has been named to Inc. Magazine,s fourth ... companies in the United States. (Logo: ... ) "The leaders of the companies ...
... have an increased risk of developing venous thromboembolism (VTE) due to ... model to predict their chance of developing blood clots, according to ... the journal of the American Society of Hematology. VTE, the formation ... percent of cancer patients and is one of the leading causes ...
Cached Medicine Technology:Despite Economic Turmoil, CIS Named to Inc. 5000 List of Fastest-Growing Private Companies in America 2Improvement in Prediction of Blood Clots in Cancer Patients 2Improvement in Prediction of Blood Clots in Cancer Patients 3
... is a modular orthotic elbow system that can ... distal humeral fractures, proximal ulnar fractures or post ... K2 is a highly flexible system that provides ... assemble the brace that best fits your patients ...
The IROM Elbow is ideal for fixed or controlled ROM in the treatment of stable supracondylar fractures, stable radial fractures, and lateral/medial epicondylitis....
A lightweight soft good with rigid elbow protection. Designed by medical professionals with your needs in mind. Provides elbow stability for mild to moderate medial/lateral and hyperextension injurie...
Innovative support that immobilizes and positions elbow at 122 to minimize stretching of ulnar nerve...
Medicine Products: