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Scientists detail urgent research agenda to address chronic disease toll
Date:8/14/2014

ther HIV is being treated or not.

Research will play a critical role in providing the evidence, strategies and tools required to address this complex challenge, said the authors, who called for visionary scientific leadership, sustained investment and attention, and the breakdown of disciplinary silos.

"Just as the advent of widespread antiretroviral treatment demanded a seismic shift in global human capacity and health systems for the emergency response to HIV, emerging chronic conditions among those with HIV in lower- and middle-income countries will demand no less," said K. M. Venkat Narayan, M.D., of Emory University, Atlanta, one of the supplement's lead authors.

While the bulk of the supplement concerned circumstances in sub-Saharan Africa, two essays described similar challenges in low-resource settings in Asia, and in Latin America and the Caribbean. The authors suggested a number of complex health and implementation science topics in developing countries that merit further study, including:

  • The lessons learned from the integration of tuberculosis care into HIV treatment should be examined to develop optimal strategies to combat chronic diseases. .
  • Drug delivery systems now devoted to antiretroviral therapy (ART) and tuberculosis medicines could add essential and affordable drugs for noncommunicable disease management, improving the long-term survival and quality of life of those living with HIV, while potentially increasing ART adherence.
  • Virally triggered cancers associated with weakened immune systems are commonamong them anal cancer, liver cancer and Hodgkin diseasebut the epidemiology of HIV-associated cancers is not well studied.
  • ART is known to increase the risk of heart failure and other cardiopulmonary conditions in high-income countries but little is known about the impact in low-resource settings, where individuals may face additional risk factors such as air pollution.
  • Depression,
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Contact: Jeff Gray
Jeffrey.Gray@nih.gov
301-496-2075
NIH/Fogarty International Center
Source:Eurekalert  

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