Navigation Links
Scientists design new anti-flu virus proteins using computational methods
Date:5/13/2011

A research article May 12 in Science demonstrates the use of computational methods to design new antiviral proteins not found in nature, but capable of targeting specific surfaces of flu virus molecules.

One goal of such protein design would be to block molecular mechanisms involved in cell invasion and virus reproduction.

Computationally designed, surface targeting, antiviral proteins might also have diagnostic and therapeutic potential in identifying and fighting viral infections.

The lead authors of the study are Sarel J. Fleishman and Timothy Whitehead of the University of Washington (UW) Department of Biochemistry, and Damian C. Ekiert from the Department of Molecular Biology and the Skaggs Institute for Chemical Biology at The Scripps Research Institute. The senior authors are Ian Wilson from Scripps and David Baker from the UW and the Howard Hughes Medical Institute.

The researchers note that additional studies are required to see if such designed proteins can help in diagnosing, preventing or treating viral illness. What the study does suggest is the feasibility of using computer design to create new proteins with antiviral properties.

"Influenza presents a serious public health challenge," the researchers noted, "and new therapies are needed to combat viruses that are resistant to existing anti-viral medications or that escape the body's defense systems."

They focused their attention on the section of the flu virus known as the hemagglutinin stem region. They concentrated on trying to disable this part because of its function in invading the cells of the human respiratory tract.

Their approach was somewhat similar to engineering a small space shuttle with the right configuration and construction, as well as recognizance and interlocking mechanisms, to dock with a troublesome space station and upset its mission. Only these scientists attempted their engineering feat at an at
'/>"/>

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Scientists Pinpoint Area of Brain That Fears Losing Money
2. Scientists Discover How HIV Is Transmitted Between Men
3. Prevention Is Key Research Goal for Premature Babies, Scientists Say
4. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
5. Scientists find donut-shaped structure of enzyme involved in energy metabolism
6. Neuroscientists reveal new links that regulate brain electrical activity
7. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. Scientists Spot Genetic Fingerprints of Individual Cancers
10. Scientists Unravel Mysteries of Intelligence
11. MSU scientists develop more effective method of predicting lead-poisoning risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists design new anti-flu virus proteins using computational methods
(Date:5/30/2015)... The results of a 40+ year ... high potential to cause mesothelioma, regardless of the volume ... on the Surviving Mesothelioma website. , The study ... Lodz, Poland found that, among the 138 cases of ... 2012, all of them happened at plants that had, ...
(Date:5/30/2015)... EHO offers a suite of online applications in ... ability to manage their drug-spend for the lowest cost ... has been able to compete with the big corporate ... among the giants of the industry. Since EHO launched ... it has simplified the way hospices can monitor patients ...
(Date:5/30/2015)... 2015 Cyclist Barry Haarde will ... the World 2015: Piles of Miles” near San ... about hemophilia and encourage individuals to support needy ... Save One Life supports nearly 1,200 impoverished children ... through direct sponsorships, scholarships and micro-enterprise grants. Hemophilia ...
(Date:5/30/2015)... FL (PRWEB) May 30, 2015 This ... partners with Pulmonary Horizons to offer one of ... effectively identify and discuss successful practices to diagnose, treat ... Attending the Pulmonary Horizons Conference is Interaction ... can address the Overall Needs of Patients with COPD," ...
(Date:5/29/2015)... Displays and Exhibits’ has recently aligned with a ... hanging signs ; making what was formerly an elite ... ceiling rigging points at a usual height of 16’-20’ are ... These signs are very unique and more visible than the ... and dismantle labor and rigging the costs far outweigh the ...
Breaking Medicine News(10 mins):Health News:New Study Finds Close Link Between Crocidolite Asbestos and Deadly Mesothelioma, According to Surviving Mesothelioma 2Health News:Barry Haarde Cycles 4,000 Miles Across the USA for Hemophilia 2Health News:Pulmonary Horizons 2nd Annual COPD Conference Miami Hilton Downtown, July 17-19, 2015 Patient Centered Cross-Continuum Education to Improve the Care of Patients with COPD 2Health News:Pulmonary Horizons 2nd Annual COPD Conference Miami Hilton Downtown, July 17-19, 2015 Patient Centered Cross-Continuum Education to Improve the Care of Patients with COPD 3Health News:Displays and Exhibits Announces New Hanging Sign Supplier 2
... ... train doctors in providing proven, non-surgical relief to millions of sufferers. , ... Dallas, TX (PRWEB) November 24, ... 2010 Frozen Shoulder Syndrome Diagnosis & Treatment seminar dates today. The three-day training ...
... , ... a Leg Up From the American Podiatric Medical Association , ... Bethesda, Md. (Vocus) November 24, 2009 -- The average person ... expert and rookie travelers alike continue making their holiday travel plans, it’s easy to forget ...
... , SAN DIEGO, Nov. 24 ... Farming, Nursery and Wellness products is pleased to announce it ... (AVA) for its Aloe365(TM) Juice product. , ... very pleased to announce that we have completed the certification ...
... WASHINGTON, Nov. 24 MinuteClinic, the pioneer and largest ... has opened its first retail health care center in ... The clinic is open seven days a week and ... Langston, Kingman Park, Atlas District, Ivy City and the ...
... , 2009 Q3 Financials, S-1 Registration Statement ... , WESTON, Fla., Nov. 24 American Scientific Resources Inc. ... current corporate update. , Since filing 2007 and 2008 audited financials ... which are all part of a long term business plan for ...
... COLUMBUS, Ga., Nov. 24 Aflac Incorporated (NYSE: AFL ... the exchange of two of its investment securities owned by Aflac. ... 2009, and the exchanges are expected to settle on December 1, ... investment in Lloyds TSB Bank plc yen-denominated, Upper Tier II perpetual ...
Cached Medicine News:Health News:OTZ Announces 2010 Frozen Shoulder Syndrome Seminar Schedule 2Health News:OTZ Announces 2010 Frozen Shoulder Syndrome Seminar Schedule 3Health News:Keep Holiday Travel Foot-Friendly 2Health News:Keep Holiday Travel Foot-Friendly 3Health News:US Farms, Inc. Receives American Vegetarian Association Certification Approval for Aloe365(TM) Juice Product 2Health News:MinuteClinic Opens First Retail Clinic in Washington, D.C. at CVS/pharmacy Store in Northeast 2Health News:MinuteClinic Opens First Retail Clinic in Washington, D.C. at CVS/pharmacy Store in Northeast 3Health News:MinuteClinic Opens First Retail Clinic in Washington, D.C. at CVS/pharmacy Store in Northeast 4Health News:American Scientific Resources Inc. Issues Corporate Update 2Health News:American Scientific Resources Inc. Issues Corporate Update 3Health News:Aflac To Exchange Two Lloyds Banking Group Securities, Enhance Risk-Based Capital Ratio 2Health News:Aflac To Exchange Two Lloyds Banking Group Securities, Enhance Risk-Based Capital Ratio 3Health News:Aflac To Exchange Two Lloyds Banking Group Securities, Enhance Risk-Based Capital Ratio 4Health News:Aflac To Exchange Two Lloyds Banking Group Securities, Enhance Risk-Based Capital Ratio 5
(Date:5/30/2015)... 2015 Caris Life Sciences®, a leading ... precision medicine, today announced the presentation of data ... Caris Molecular Intelligence®, the company,s panomic comprehensive tumor ... share histological features. In separate presentations at the ... Oncology (ASCO) in Chicago, Ill. ...
(Date:5/29/2015)... May 29, 2015  Excite Medical was established by ... the years, Excite Medical, under the leadership of ... company, with a solid track record of providing unparalleled ... and distributor base.  Photo - ... Medical has been possible, in large part, due to ...
(Date:5/29/2015)... N.J. , May 29, 2015 A six-hour ... is being presented at the Cannabis World Congress ... New York, NY .  Taking place on ... a dedicated day of education at the leading event on ... Led by Clover Leaf University, the first ...
Breaking Medicine Technology:Caris Molecular Intelligence Multi-Platform Tumor Profiling Facilitates Comparisons between Tumors that Share Histological Features 2Caris Molecular Intelligence Multi-Platform Tumor Profiling Facilitates Comparisons between Tumors that Share Histological Features 3Caris Molecular Intelligence Multi-Platform Tumor Profiling Facilitates Comparisons between Tumors that Share Histological Features 4Caris Molecular Intelligence Multi-Platform Tumor Profiling Facilitates Comparisons between Tumors that Share Histological Features 5Caris Molecular Intelligence Multi-Platform Tumor Profiling Facilitates Comparisons between Tumors that Share Histological Features 6Cannabis Business Certification and Career Workshops Presented at New York Trade Show & Conference 2Cannabis Business Certification and Career Workshops Presented at New York Trade Show & Conference 3Cannabis Business Certification and Career Workshops Presented at New York Trade Show & Conference 4
... AMSTERDAM, October 8 BMEYE B.V., ... its Series B financing round, raising EUR 6 million. ... Partners participated in the,financing, along with other existing BMEYE ... BMEYE has successfully been selling Nexfin(TM), ...
... Media, LLC (AHM) has acquired Ephikacy, LLC, the Chicago-based ... pharmaceutical and life sciences industries. , Advanced Health Media ... automation and compliance management systems to more than 50 ... 200 brands. The addition of Ephikacy,s product and ...
Cached Medicine Technology:BMEYE B.V. Completes EUR 6 Million Series B Financing Round 2BMEYE B.V. Completes EUR 6 Million Series B Financing Round 3Advanced Health Media Announces Acquisition of Ephikacy, LLC 2Advanced Health Media Announces Acquisition of Ephikacy, LLC 3
Gills Colibri forceps, very fine pointed tips....
Fine tying forceps, curved tips, wide handle....
Castroviejo tying forceps, tying platforms, straight, 0.3 mm teeth....
Microsurgical curved forceps made of titanium has curved shafts with smooth working surface. TCI working parts 6 mm from tips with round handle, diam. 6 mm, overall length 116 mm....
Medicine Products: