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Scientists decode secrets of a very common virus that can cause cancer
Date:12/15/2010

ell growth is related to several types of cancer, including post-transplant lymphoproliferative disorder, in which a transplant patient gets a form of lymphoma because of B-cell proliferation, and HIV-associated B-cell lymphomas among others.

"This finding can be extended to the general case of any oncogene being activated that might start the process of tumor formation," Luftig said. "About 20 percent of all human cancers are caused by infectious agents, where about 80 percent of these infections are viral." Another example of a viral infection leading to cancer is the human papillomavirus, implicated in cervical cancer.

Epstein-Barr virus infection can mean different courses for different people. In children 4-5 years old, a first infection with the virus may cause a mild illness, but if this primary infection happens during adolescence, the person may suffer a case of mononucleosis with heavy fatigue and other symptoms. In immune-compromised people, the virus can do much worse damage and cause forms of lymphoma.


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Contact: Mary Jane Gore
mary.gore@duke.edu
919-660-1309
Duke University Medical Center
Source:Eurekalert

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