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Scientists debate CDC recommendations during meningitis outbreak
Date:2/5/2013

sease," writes Stevens.

In the second commentary, a rebuttal of the Stevens' commentary, a group of scientists including one CDC official defend the CDC's recommendation against prophylactic antifungal therapy, describing the CDC's decision analysis model.

"Most of these cases resulted from epidural injections; these patients did not intentionally receive intrathecal injections, as suggested by Stevens," write the scientists. "Clinicians must carefully weigh the benefit of treatment of asymptomatic patients with the significant expense associated with drug acquisition, monitoring drug levels and substantial drug-drug interactions. For this reason, CDC chose to recommend careful clinical evaluation and imaging for high risk patients, independent of symptoms, with the goal of finding early indications of infection."

The manuscripts of the commentaries are available online at http://bit.ly/asmpr0205a and http://bit.ly/asmpr0205b. Formal publication is scheduled for the April 2013 issue of Antimicrobial Agents and Chemotherapy.


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Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

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