Navigation Links
Scientists capture single cancer molecules at work
Date:12/8/2011

This press release is available in French.

Researchers have revealed how a molecule called telomerase contributes to the control of the integrity of our genetic code, and when it is involved in the deregulation of the code, its important role in the development of cancer. The University of Montreal scientists involved explain how they were able to achieve their discovery by using cutting edge microscopy techniques to visualize telomerase molecules in real time in living cells in Molecular Cell on December 9, 2011.

"Each time our cells divide, they need to completely copy the genomic DNA that encodes our genes, but the genome gets shorter each time until the cell stops dividing," said Dr. Pascal Chartrand, a biochemistry professor at the University of Montreal and a senior author of the study. "However, the telomerase molecules can add bits of DNA called telomeres to the ends of our genome. Telomeres prevent the genome from deteriorating or joining up with other pieces of DNA, allowing cells to divide indefinitely and become cancerous. Normally, the telomerase gene is not active, but how it is controlled is poorly understood. One difficulty has been that we need to see exactly what individual telomerase molecules are doing on our genome and when." Franck Gallardo, the study's lead author, added that the team was able to apply techniques from other work that the team was doing in their lab. "We could in fact visualize what individual telomerases were doing in cells," he said.

In collaboration with Nancy Laterreur and Dr. Raymund Wellinger of the Universit de Sherbrooke, Dr. Gallardo was able to tag telomerase with fluorescent proteins, which allowed them to visualize telomerase in single living cells. With this technological breakthrough, they observed that, contrary to previous theories, several molecules of telomerase cluster on
'/>"/>

Contact: Julie Gazaille
j.cordeau-gazaille@umontreal.ca
University of Montreal
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Scientists Pinpoint Area of Brain That Fears Losing Money
2. Scientists Discover How HIV Is Transmitted Between Men
3. Prevention Is Key Research Goal for Premature Babies, Scientists Say
4. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
5. Scientists find donut-shaped structure of enzyme involved in energy metabolism
6. Neuroscientists reveal new links that regulate brain electrical activity
7. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. Scientists Spot Genetic Fingerprints of Individual Cancers
10. Scientists Unravel Mysteries of Intelligence
11. MSU scientists develop more effective method of predicting lead-poisoning risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... NY (PRWEB) May 05, 2015 ... IVF Clinic in Greece, an experienced team of ... treatment of infertility for patients around the globe. , ... with VisitandCare.com. Greece unquestionably remains a global leader in ... talented and hard-working fertility specialists in the world who ...
(Date:5/5/2015)... York, New York (PRWEB) May 05, 2015 ... lawsuits ( http://www.testosteronelawsuithub.com/ ) filed on behalf ... complications due to their use of prescription ... in the federal multidistrict litigation underway in ... According to court documents dated May 1st, ...
(Date:5/5/2015)... Baptist Medical Center Jacksonville’s cancer program has ... the American College of Surgeons. , To earn the ... 30 Commission on Cancer quality care standards, be evaluated ... levels of excellence in the delivery of comprehensive patient-centered ... care locally at a CoC-accredited cancer center, they are ...
(Date:5/5/2015)... Atlanta, Georgia (PRWEB) May 05, 2015 ... Software of Victoria BC announced the Skedans Sensor ... The platform, for mobile and web app developers, provides ... from airborne and mobile sensors. , The Skedans Sensor ... at the intersection of the Internet of Things, Web ...
(Date:5/5/2015)... May 05, 2015 MAP Health Management, ... revenue cycle management for addiction treatment facilities, announced today ... President of Business Development. Mr. Mooney, who has more ... field, will be responsible for developing new strategic partnerships ... MAP’s core products and new initiatives. , Prior to ...
Breaking Medicine News(10 mins):Health News:Maternity Health IVF Clinic in Greece Demonstrates Industry-Leading Fertility Technology 2Health News:Maternity Health IVF Clinic in Greece Demonstrates Industry-Leading Fertility Technology 3Health News:Federal Testosterone Lawsuit Defendants Recently Submitted Answers to Master Long Form Complaint 2Health News:Federal Testosterone Lawsuit Defendants Recently Submitted Answers to Master Long Form Complaint 3Health News:Federal Testosterone Lawsuit Defendants Recently Submitted Answers to Master Long Form Complaint 4Health News:Baptist Medical Center Jacksonville Receives National Cancer Reaccreditation 2Health News:Baptist Medical Center Jacksonville Receives National Cancer Reaccreditation 3Health News:Baptist Medical Center Jacksonville Receives National Cancer Reaccreditation 4Health News:Skedans Systems Announces Skedans Sensor Collaboration Platform at AUVSI's Unmanned Systems 2015 in Atlanta 2Health News:Jimmy Mooney, an Addiction Treatment Veteran, Named Vice President of Business Development at MAP Health Management, LLC 2
... Risk highest among those who had mechanical ventilation, study finds ... from the hospital after a stay in the intensive care ... following three years, new research shows. , The risk of ... while in the ICU, according to the report published in ...
... would lower people,s quality of life, , TUESDAY, March 2 ... by kidney failure yield mixed results, depending on the severity ... on dialysis with severe anemia, according to the study, tend ... -- known as erythropoiesis-stimulating agents (ESAs) and marketed as Epogen, ...
... , Irvine, Calif., March 1, 2010 UC Irvine neurobiologists ... health and, therefore, that mental stimulation could limit the ... Using a novel visualization technique they devised to study memory, ... found that everyday forms of learning animate neuron receptors that ...
... ... ... , ... WASHINGTON , March 2 Vice Admiral ...
... ... ... , ... ...
... nanoparticle growing in popularity as a bactericidal agent has been ... University study. Tested on fathead minnows ╨ an organism ... life -- nanosilver suspended in solution proved toxic and even ... settle, the solution became several times less toxic but still ...
Cached Medicine News:Health News:Death After Discharge Rates Higher in Elderly ICU Patients 2Health News:For Some on Dialysis, Anemia Drugs Pose Risks 2Health News:For Some on Dialysis, Anemia Drugs Pose Risks 3Health News:For Some on Dialysis, Anemia Drugs Pose Risks 4Health News:Learning keeps brain healthy, UCI researchers find 2Health News:AMA Honors Vice Admiral John Mateczun, M.D., With Top Government Service Award 2Health News:AMA Honors Vice Admiral John Mateczun, M.D., With Top Government Service Award 3Health News:LG Electronics Expands Benefits of Healthcare HDTVs With New Compliance Ratings at HIMSS 2010 2Health News:LG Electronics Expands Benefits of Healthcare HDTVs With New Compliance Ratings at HIMSS 2010 3Health News:LG Electronics Expands Benefits of Healthcare HDTVs With New Compliance Ratings at HIMSS 2010 4Health News:LG Electronics Expands Benefits of Healthcare HDTVs With New Compliance Ratings at HIMSS 2010 5Health News:Popular nanoparticle causes toxicity in fish, study shows 2
(Date:5/5/2015)... and ST. LOUIS , ... blood pressure or high cholesterol may achieve better health ... networks, according to early results of a unique program ... ESRX ). "Pharmacists are one of ... frequent interactions with our members presents enormous opportunities to ...
(Date:5/5/2015)... Lymphatic pump treatment (LPT) shows promise in ... a new study published in The Journal of ... performed LPT on infected rats three times a day ... to treat pneumonia. After 96 hours, over 60 percent ... 25 percent of rats who received levofloxacin alone. ...
(Date:5/5/2015)... PORTLAND, Oregon , May 5, 2015 ... market in the US, Europe , ( ... , Spain , UK) and ... and etiology are reviewed. The report provides the 5-year test volume ... Ag, HCV, HCV NAT, Anti-HBc, Anti-HBs, Anti-HAV, Hepatitis Delta, HBc Ag, ...
Breaking Medicine Technology:SCAN Health Plan, Express Scripts' Quality Network Improves Medicare Beneficiary Health 2SCAN Health Plan, Express Scripts' Quality Network Improves Medicare Beneficiary Health 3SCAN Health Plan, Express Scripts' Quality Network Improves Medicare Beneficiary Health 4Lymphatic Pump Treatment Enhances Antibiotic Effectiveness for Treating Pneumonia 22015 Opportunities in the Global Hepatitis Diagnostic Testing Market: Big Market Research 22015 Opportunities in the Global Hepatitis Diagnostic Testing Market: Big Market Research 3
For the quantitative determination of total protein in serum. Linearity: 1-15 g/dl....
... the quantitative determination of urea ... lag phase of less than ... phase of at least 240 ... 100 mg/dL (35.6 mmol/L urea) ...
For the quantitative determination of direct bilirubin in human serum. Linearity: 20 mg/dl...
For the quantitative determination of direct & total bilirubin in serum. Modified Malloy-Evelyn Diazotization Method. Endpoint Reaction Product measured at 540 nm. Linearity: 20 mg/dl...
Medicine Products: