Navigation Links
Scientists advance safety of nanotechnology
Date:6/10/2009

Scientists have identified for the first time a mechanism by which nanoparticles cause lung damage and have demonstrated that it can be combated by blocking the process involved, taking a step toward addressing the growing concerns over the safety of nanotechnology.

Nanotechnology, the science of the extremely tiny (one nanometre is one-billionth of a metre), is an important emerging industry with a projected annual market of around one trillion US dollars by 2015. It involves the control of atoms and molecules to create new materials with a variety of useful functions, including many that could be exceptionally beneficial in medicine. However, concerns are growing that it may have toxic effects, particularly damage to the lungs. Although nanoparticles have been linked to lung damage, it has not been clear how they cause it.

In a study published online today (Thursday 11 June) in the newly launched Journal of Molecular Cell Biology [1] Chinese researchers discovered that a class of nanoparticles being widely developed in medicine - ployamidoamine dendrimers (PAMAMs) cause lung damage by triggering a type of programmed cell death known as autophagic cell death. They also showed that using an autophagy inhibitor prevented the cell death and counteracted nanoparticle-induced lung damage in mice.

"This provides us with a promising lead for developing strategies to prevent lung damage caused by nanoparticles. Nanomedicine holds extraordinary promise, particularly for diseases such as cancer and viral infections, but safety concerns have recently attracted great attention and with the technology evolving rapidly, we need to start finding ways now to protect workers and consumers from any toxic effects that might come with it," said the study's leader, Dr. Chengyu Jiang, a molecular biologist at the Chinese Academy of Medical Sciences in Beijing, China.

The first nanomaterial
'/>"/>

Contact: Emma Ross
rosswrite@mac.com
Oxford University Press
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. UNC scientists identify growth factor as possible cancer drug target
2. World first: Chinese scientists create pig stem cells
3. Scientists use bed bugs own chemistry against them
4. NYP/Weill Cornell physician-scientists present at 2009 American Transplant Congress in Boston
5. Scripps Florida scientists devise accelerated method to determine infectious prion strains
6. Scientists find city rats are loyal to their hoods
7. Scientists find shared genetic link between the dental disease periodontitis and heart attack
8. Photos: The Nations Leading Scientists and Top Rock Stars Shine a Spotlight on the Promise of Medical Research
9. Scientists develop mathematical model to predict the immune response to influenza
10. Americas Top Young Scientists to Receive Scholarships for Winning Eggs-Periments
11. Scientists identify gene in breast cancer pathway
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... in California, the percentage undergoing a double mastectomy increased ... not associated with a lower risk of death than ... the September 3 issue of JAMA . The ... one breast was associated with a higher risk of ... , Randomized trials have demonstrated similar survival for patients ...
(Date:9/2/2014)... The Dream2Walk Foundation along with Gas Monkey ... 2014 during Spinal Cord Injury Awareness Month featuring full band ... Chuck Ligon. Linear Automotive will be there hosting a Hot ... open at 2pm. The car show is Pre 1964 only, ... to the concert. There will be trophies for top 3 ...
(Date:9/2/2014)... Sept. 2, 2014 (HealthDay News) -- Melatonin supplements did ... hip fractures, a new study found. Many older ... delirium due to disruption of their normal sleep-wake cycle. ... factor that contributes to delirium, but there has been ... patients. This study included 378 patients, average age ...
(Date:9/2/2014)... (Sept. 2, 2014) Measuring the levels of sex hormones ... sudden cardiac arrest, a heart rhythm disorder that is fatal ... published online by the peer-reviewed journal Heart Rhythm , ... hormone, were found in men who had a sudden cardiac ... were strongly associated with greater chances of having a sudden ...
(Date:9/2/2014)... When weather conditions are right, tornadoes can occur anywhere ... path of destruction. In fact, the United States leads the ... per year. Rainbow International offers the following safety tips on ... , Select a safe place such as a ... no windows to stay during the storm. If a tornado ...
Breaking Medicine News(10 mins):Health News:Increase seen in use of double mastectomy 2Health News:Increase seen in use of double mastectomy 3Health News:Gas Monkey Hosts Concert in Dallas Benefiting Dream2Walk Foundation with Linear Automotive 2Health News:Study links sex hormone levels in the blood to risk of sudden cardiac arrest 2Health News:Act Quickly in Case of Tornado: Rainbow International® Offers Tips on How to Be Prepared for a Tornado 2
... prescription drugs, study says , , MONDAY, March 24 (HealthDay ... their doctors end up having significantly higher out-of-pocket costs ... free samples, a new study finds. , In ... in out-of-pocket costs on prescription drugs in the six ...
... March 24 /Xinhua-PRNewswire-FirstCall/ -- China,Nepstar Chain Drugstore Ltd. (NYSE: ... drugstore chain in China based on the number of,directly ... has,declared a cash dividend on its ordinary share of ... full year 2007. The cash dividend is payable on,or ...
... 24 "Going head-to-head with your child,can be more stacked ... extra reading at bedtime and, before you know it, she,ll ... can,t refuse.,Well, if I can,t stay up late to have ... you owe me a back rub and two books before ...
... HeartWare Inc. (ASX: HTW),a developer and manufacturer ... failure, today announced it has selected Allen & ... corporate communications.,Allen & Caron Inc has offices in ... Chief Executive Douglas Godshall said: "There is a ...
... vitro model (cell culture) research currently underway at the Peninsula ... to identify and develop therapies for the treatment of multiple ... mutations affecting a protein called merlin, which in turn cause ... in the brain. Schwann cells produce the sheaths that surround ...
... From ... its Biodefense and Pandemic Fund, SAN DIEGO, March 24 ... million Series B financing to advance the,clinical development of its ... financing was led by Kleiner,Perkins, Caufield and Byers (KPCB). New ...
Cached Medicine News:Health News:Free Drug Samples Hike Out-of-Pocket Costs 2Health News:Free Drug Samples Hike Out-of-Pocket Costs 3Health News:China Nepstar Chain Drugstore Announces Dividend 2Health News:China Nepstar Chain Drugstore Announces Dividend 3Health News:HOW TO UNSPOIL YOUR CHILD FAST: Harvard Medical School Psychologist Writes Book to Guide and Motivate Parents and Support the Children's Defense Fund 2Health News:HeartWare Selects Allen & Caron for Investor Relations and Corporate Communications 2Health News:Research to lead to brain tumor therapies 2Health News:Research to lead to brain tumor therapies 3Health News:Trius Raises $30 Million in Series B Financing 2
(Date:9/2/2014)... , Spanien und CALGARY, Alberta , ... Vorgestellt in der "State of the Art and ...    Resverlogix Corp. (TSX: RVX) gab heute ... Affairs bei Resverlogix, beim Kongress des europäischen Kardiologenverbandes (ESC) ... Vortrag gehalten hat. In seinem Vortrag mit dem Titel ...
(Date:9/2/2014)... September 2, 2014 According ... Market Research "Latin America Home Healthcare Market (By ... Healthcare Devices, Mobility Assist Devices and Medical Supplies; ... Infusion Therapy and Unskilled Home Healthcare Services) - ... 2014 - 2020" the Latin American Home Healthcare ...
(Date:9/2/2014)... , Spanje, September 2, 2014 ... GARFIELD AF Registry bij het ESC CONGRESS ... bij patiënten met risico op beroerte in ... Gegevens van bijna 12.500 patiënten ingeschreven ... FIELD-Atrial Fibrillation (GARFIELD-AF), een innovatief, onafhankelijk initiatief ...
Breaking Medicine Technology:RVX-208 führt bei Patienten mit Diabetes mellitus zu einer Verringerung des relativen Risikos von gravierenden unerwünschten Herzkreislaufereignissen um 77 % 2RVX-208 führt bei Patienten mit Diabetes mellitus zu einer Verringerung des relativen Risikos von gravierenden unerwünschten Herzkreislaufereignissen um 77 % 3RVX-208 führt bei Patienten mit Diabetes mellitus zu einer Verringerung des relativen Risikos von gravierenden unerwünschten Herzkreislaufereignissen um 77 % 4RVX-208 führt bei Patienten mit Diabetes mellitus zu einer Verringerung des relativen Risikos von gravierenden unerwünschten Herzkreislaufereignissen um 77 % 5RVX-208 führt bei Patienten mit Diabetes mellitus zu einer Verringerung des relativen Risikos von gravierenden unerwünschten Herzkreislaufereignissen um 77 % 6Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 2Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 3Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 4Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 5Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 6Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 2Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 3Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 4Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 5Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 6Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 7Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 8Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 9Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 10
... /PRNewswire-Asia/ -- Winner Medical Group Inc. (Nasdaq: WWIN ... medical dressings, medical disposables and non-woven fabric made from 100% ... team will present at the 2011 Brean Murray, Carret & ... 27 and 28, 2011 at the JW Marriott Hotel located ...
... Ingelheim announced today that they will launch a three-year ... world.  The "Making More Health" initiative will promote healthy ... most promising solutions to challenging health problems. ... programs aimed at identifying innovative health solutions, including the ...
Cached Medicine Technology:Winner Medical to Present at Brean Murray, Carret & Co. Beijing China Growth Conference 2Winner Medical to Present at Brean Murray, Carret & Co. Beijing China Growth Conference 3Ashoka and Boehringer Ingelheim Announce a Global Partnership for "Making More Health" 2Ashoka and Boehringer Ingelheim Announce a Global Partnership for "Making More Health" 3
Exidine® 2% CHG Brushless Surgical Scrub offers exceptional persistence and broad-spectrum antimicrobial activity....
... FDA approved, Avagard antiseptic hand prep ... hand scrub brushes and antimicrobial soaps. ... hands for surgery, it's fast-acting and ... for up to six hours without ...
... antimicrobial skin cleanser will not leave your ... frequent washings. With persistent Antimicrobial action, CHG ... microorganisms, including gram-negative and gram-positive bacteria, fungi, ... a 15 second hand wash. The solution ...
Upon application to intact skin, Skin-Prep* protective wipes forms a protective film that prepares the skin for the attachment of drainage tubes, external catheters, adhesive dressings and can be...
Medicine Products: