Navigation Links
Scientists Spot Source of Hurdle to AIDS Vaccine
Date:12/18/2009

Immune system turns off antibodies that could block HIV, study finds

FRIDAY, Dec. 18 (HealthDay News) -- Researchers have identified the cause of a major hurdle in efforts to develop an AIDs vaccine.

In tests with mice, the scientists found that the immune system can produce B cells with the potential to make powerful antibodies against HIV, the virus that causes AIDS. But the immune system mistakenly perceives these cells as harmful and destroys them before they have a chance to mature.

The study was published in this week's online issue of the Proceedings of the National Academy of Sciences.

"This work may mean that we need to think and act very differently in envisioning how a successful vaccine may work," study author Laurent Verkoczy, an assistant professor of medicine at Duke University Medical Center, said in a news release from the school.

"The good news is that while about 85 percent of the 'right' kind of B cells are eliminated, about 15 percent survive and wind up in circulating blood, but are turned off. One goal in vaccine design may be to figure out how to wake them up so they can go to work," Verkoczy explained.

The researchers plan to conduct mouse studies to test ways to teach the immune system to allow production of antibodies that can block HIV.

More information

The U.S. Department of Health and Human Services has more about AIDS vaccines.



-- Robert Preidt



SOURCE: Duke University Medical Center, news release, Dec. 15, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. BioProcess International Launches a New and Improved Website for Biopharmaceutical Managers and Scientists
2. Scientists Link Molecule to Severe Swine Flu
3. Scientists use cell phone records to predict spread of malaria
4. Scientists uncover protective mechanism against liver cancer
5. UNC scientists coordinate study of link between insulin use and cancer in people with diabetes
6. Doctors and Scientists Create New Society to Promote Non-Animal Toxicology Testing Methods
7. NeuroFocus Adds Two More of the Worlds Leading Neuroscientists to its Advisory Board
8. Scripps Research scientists reveal key structure from ebola virus
9. Stand Up To Cancer Funds High-risk/High-reward Cancer Research by 13 Young Scientists
10. Caltech scientists show how ubiquitin chains are added to cell-cycle proteins
11. Vanderbilt scientists report first effective medical therapy for rare stomach disorder
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published June 14 ... The article goes on to state that individuals are now more comfortable seeking to ... operations such as calf and cheek reduction. The Los Angeles area medical group, Beverly ...
(Date:6/24/2016)... ... ... Marcy was in a crisis. Her son James, eight, was out of control. Prone to ... , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there ... my other children and say he was going to kill them. If we were ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all ... brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary ...
(Date:6/24/2016)... ... ... People across the U.S. are sharpening their pencils and honing their writing ... which patients and their families pay tribute to a genetic counselor by nominating him ... Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, Genome ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative Solutions today ... cultivation and processing operations at its production facility, and opened its first two ... the manufacturer of a complete system of proactive air and surface purification solutions ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Calif. , June 23, 2016 Any dentist ... many challenges of the current process. Many of them do ... of the technical difficulties and high laboratory costs involved. And ... to offer it at such a high cost that the ... it. Dr. Parsa Zadeh , founder of ...
(Date:6/23/2016)... -- Research and Markets has announced the addition ... - Forecast to 2022" report to their offering. ... to date financial data derived from varied research sources to ... potential impact on the market during the next five years, ... of sub markets, regional and country level analysis. The report ...
(Date:6/23/2016)... June 23, 2016 , , ... July 7, 2016 , , , , LOCATION: , , ... , , , EXPERT PANELISTS:  , , , Frost & ... Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, ... The global pharmaceutical industry is witnessing an exceptional era. Several new ...
Breaking Medicine Technology: