Navigation Links
Scientists Spot Possible Target in Ovarian Cancer
Date:7/12/2011

TUESDAY, July 12 (HealthDay News) -- Researchers seeking a way to beat cancer have found that a particular gene, known as PAX8, is altered in a significant number of ovarian tumors, according to a new study.

The research is part of Project Achilles, a comprehensive effort by scientists from the Broad Institute of MIT and Harvard, and the Dana-Farber Cancer Institute to identify weaknesses in cancers.

After analyzing the cells of more than 100 tumors, including 25 ovarian cancer tumors, the researchers reported that identifying genes like PAX8 might help in the battle against certain types of cancer.

"In this project, we're looking for all of the Achilles' heels of cancer. That is to say, we're looking for any instance where you inactivate a gene and affect the survival of cancer cells," William Hahn, a senior associate member of the Broad Institute and an associate professor at Dana-Farber and Harvard Medical School, said in an institute news release.

The researchers suppressed more than 10,000 genes in an attempt to find those needed for cancer cells to grow and survive. The PAX8 gene was identified in nearly one-fifth of the ovarian tumors analyzed.

"Not only can we characterize what genes are mutated or altered, but we can also simultaneously assess which of those are important functionally," Hahn said.

In identifying these specific genes, the investigators hope to predict the effect of treatments targeting specific genes. They also noted that going forward, it may be more telling to identify tumors based on genetic mutations rather than their organ or tissue of origin.

"Many of us in the genomics field . . . were thinking that maybe someday, we won't care about the organs that cancers come from, that we will only care about the genetic mutations that drive them," said Hahn.

In the near future, the researchers said they plan further investigation of the notoriously treatment-resis
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Scientists Pinpoint Area of Brain That Fears Losing Money
2. Scientists Discover How HIV Is Transmitted Between Men
3. Prevention Is Key Research Goal for Premature Babies, Scientists Say
4. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
5. Scientists find donut-shaped structure of enzyme involved in energy metabolism
6. Neuroscientists reveal new links that regulate brain electrical activity
7. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. Scientists Spot Genetic Fingerprints of Individual Cancers
10. Scientists Unravel Mysteries of Intelligence
11. MSU scientists develop more effective method of predicting lead-poisoning risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Spot Possible Target in Ovarian Cancer
(Date:8/29/2015)... NY (PRWEB) , ... August 29, 2015 , ... Next ... end of summer (which astronomically, officially ends on September 22nd this year). For IT ... cyber security hangovers linger on which could prove far more costly than a simple ...
(Date:8/29/2015)... Calgary, AB (PRWEB) , ... August 29, 2015 ... ... congestive heart failure, angina, chronic obstructive pulmonary disease (including emphysema), or asthma, are ... conditions such as angina, previous heart attack, heart failure or heart-rhythm problems (arrhythmia ...
(Date:8/29/2015)... ... , ... The popular television program VOICES IN AMERICA, hosted by legendary star ... devoting an entire short segment to the subject of diabetes. Diabetes is a debilitating ... daily basis, but recent advancements in medical science may prove to be a significant ...
(Date:8/28/2015)... (PRWEB) , ... August 29, 2015 , ... Rio ... higher learning and the student experience as part of the EDUCAUSE - Next Generation ... Foundation . , This is the third Breakthrough Models Incubator hosted by ...
(Date:8/28/2015)... ... August 28, 2015 , ... An online provider of CPAP machines, ... purchase of CPAP equipment more affordable by offering shipping at no cost to you, ... products and orders of any size. My Cpap Store is located in Las Vegas, ...
Breaking Medicine News(10 mins):Health News:Business Cyber Security – Come Out of the Summer with a Clean Slate 2Health News:Business Cyber Security – Come Out of the Summer with a Clean Slate 3Health News:Business Cyber Security – Come Out of the Summer with a Clean Slate 4Health News:Heart Fit Clinic Sounds the Alarm on Forest Fire Smoke and Chronic Heart Disease in Calgary Area 2Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 2Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 3Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 4Health News:My Cpap Store Now Offering Delivery Special 0 Cost to You 2
... , SAN DIEGO, Nov. 24 US ... Nursery and Wellness products is pleased to announce it has ... for its Aloe365(TM) Juice product. , Yan ... pleased to announce that we have completed the certification process ...
... , 2009 Q3 Financials, S-1 Registration Statement being Prepared ... WESTON, Fla., Nov. 24 American Scientific Resources Inc. (Pink Sheets: ... update. , Since filing 2007 and 2008 audited financials on Pinksheets ... all part of a long term business plan for the Company. ...
... BATTLE CREEK, Mich., Nov. 24 The following should be ... W.K. Kellogg Foundation: , The W.K. Kellogg Foundation commends Congress ... substantially strengthen oral health care for our most vulnerable children. ... a high water mark for oral health legislation, with more ...
... reasoning that testing less is OK , TUESDAY, Nov. 24 ... upended in the past two weeks. , Not only did ... age at which it recommends women get their first mammogram ... and Gynecologists (ACOG) decided that adolescents should be spared the ...
... Health ... suggests the need to re-examine reimbursement. , ... Alpharetta, GA (Vocus) November 24, 2009 -- The proposed legislation ... insurers, legislators and policy makers all weighing in with their views on what will ...
... ... advice on the topic of most concern to MyShrink readers. a - ban,- don: ... ... 2009 -- Dr. Suzanne LaCombe and Dr. Carole Gaato today announced the second webinar ...
Cached Medicine News:Health News:US Farms, Inc. Receives American Vegetarian Association Certification Approval for Aloe365(TM) Juice Product 2Health News:American Scientific Resources Inc. Issues Corporate Update 2Health News:American Scientific Resources Inc. Issues Corporate Update 3Health News:Statement of Support: Strengthening Oral Health Care is Key Part of Health Reform 2Health News:Recent Cancer Screening Changes Leave Many Confused 2Health News:Recent Cancer Screening Changes Leave Many Confused 3Health News:Recent Cancer Screening Changes Leave Many Confused 4Health News:Jackson & Coker Industry Report Addresses Health Care Reform 2Health News:Jackson & Coker Industry Report Addresses Health Care Reform 3Health News:Home For the Holidays: MyShrink.com Announces the Second in its Successful Six-Part Webinar Series: "Abandonment: The Hidden Fear" 2
(Date:8/28/2015)... 2015 Research and ... of the "Investigation Report on China,s Quetiapine ... Developed by AstraZeneca plc, quetiapine (under the ... for the treatment of schizophrenia. Approved by CFDA ... in the Catalogue of Drugs for the Basic ...
(Date:8/28/2015)... August 28, 2015 The scientific team ... with one of the leading academics in the field of ... record holder in life extension for model animals - 10 ... of aging and age-related diseases, primarily, around the stability and ... just been published as "Stability analysis of a model gene ...
(Date:8/28/2015)... Denmark and ATLANTA ... 31, 2015 the US Food and Drug Administration (FDA) cleared ... Depressive Disorder in adult patients who have failed to receive ... TMS is a non-invasive technique for stimulating neural tissue in ... Major Depressive Disorder. The procedure has been proven safe and ...
Breaking Medicine Technology:China Quetiapine Market Investigation Report 2010-2019 2Gero: Physics Meets Biology to Help Defeat Aging 2Gero: Physics Meets Biology to Help Defeat Aging 3Therapy System for Treating Major Depressive Disorder Receives FDA Clearance 2Therapy System for Treating Major Depressive Disorder Receives FDA Clearance 3
... enrollment is complete in,the first randomized, prospective, ... and cost-effectiveness of a physiologic-guided,percutaneous coronary intervention ... with multivessel coronary artery disease (CAD). Bernard ... today at the Transcatheter,Cardiovascular Therapeutics symposium (TCT ...
... Phase III - - Conference Call Scheduled ... LA JOLLA, Calif., Oct. 22 TorreyPines,Therapeutics, Inc. (Nasdaq: ... endpoint in a 306-patient, Phase IIb clinical trial for ... study, which evaluated,tezampanel administered subcutaneously, the 40 mg dose ...
Cached Medicine Technology:Patient Enrollment Complete in First Trial to Compare Physiologic Guidance vs. Angiographic Guidance of Stent Deployment in Patients with Multivessel Disease 2Tezampanel Meets Primary Endpoint in Phase IIb Clinical Trial in Acute Migraine Headache 2Tezampanel Meets Primary Endpoint in Phase IIb Clinical Trial in Acute Migraine Headache 3Tezampanel Meets Primary Endpoint in Phase IIb Clinical Trial in Acute Migraine Headache 4Tezampanel Meets Primary Endpoint in Phase IIb Clinical Trial in Acute Migraine Headache 5Tezampanel Meets Primary Endpoint in Phase IIb Clinical Trial in Acute Migraine Headache 6Tezampanel Meets Primary Endpoint in Phase IIb Clinical Trial in Acute Migraine Headache 7Tezampanel Meets Primary Endpoint in Phase IIb Clinical Trial in Acute Migraine Headache 8
... Rim Implants provide the surgeon ... augmentation of the inferior and ... or secondary rim repair. The ... projection and extends around the ...
Flattened points in vertical plane, straight shafts, cross action, round handle....
Phaco chopper delicate rounded tip....
Nucleus chopper....
Medicine Products: