Navigation Links
Scientists Spot Key to Cystic Fibrosis Infections
Date:12/16/2008

Targeting pigments in mucus could fight deadly,,bacteria in lungs

TUESDAY, Dec. 16 (HealthDay News) -- Blue-green pigments called phenazines that stain the mucus in the lungs of cystic fibrosis patients are signaling molecules that could spur dangerous infections, researchers say.

The pigments may enable infectious Pseudomonas aeruginosa bacteria to form into structured communities, according to a Massachusetts Institute of Technology (MIT) study.

The finding could lead to the development of drugs that target phenazines to treat P. aeruginosa infections in CF patients, said the researchers, who presented their findings Tuesday at the annual meeting of the American Society for Cell Biology.

Healthy people can easily cope with P. aeruginosa, but it's the leading cause of death among CF patients, because it chokes their lungs with sticky mucus.

It's long been believed that phenazines were antibiotics, generated by P. aeruginosa to kill off its bacterial competitors in the lungs.

In laboratory studies, the MIT researchers found that phenazines create a smooth biofilm surface under which a P. aeruginosa colony can thrive. The less phenazine there is, the weaker the colony surface.

"We have a long way to go before being able to test this idea, but the hope is that if survival in the lung is influenced by phenazine -- or some other electron-shuttling molecule or molecules -- tampering with phenazine trafficking might be a potential way to make antibiotics more effective," study leader Dianne K. Newman, a professor of biology and geobiology, explained in an MIT news release.

More information

The March of Dimes has more about cystic fibrosis.



-- Robert Preidt




'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Scientists, Physicians, Health, and Environmental Justice Advocates to New Obama EPA Director: We Look Forward to Toxic Chemical Regulatory Reform
2. Seven life scientists get research boost to set up in Europe
3. UC San Diego scientists developing brain imaging methods for studying natural human behavior
4. Scientists ID Enzyme Causing Brain Cell Death
5. NASA scientists provide update on existing remote sensing technology programs and new projects
6. Scientists ID Protein Aiding Breast Cancer Spread
7. UCLA scientists prove endothelial cells give rise to blood stem cells
8. Scientists at CSHL uncover new RNA processing mechanism and a new class of small RNAs
9. CSHL scientists show how a protein that determines cell polarity prevents breast cancer
10. Carnegie Mellon scientists offer explanation for face blindness
11. Scientists ID Uterine Muscle Switch for Contractions
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Spot Key to Cystic Fibrosis Infections
(Date:3/29/2015)... Franklin, TN (PRWEB) March 29, 2015 ... for several PT Online Continuing Education Courses . ... - 10.0 hours of CME - TPTA, approval # ... Master the evaluation of the shoulder complex - 10.5 ... Course Approved #56400TX , Examination and Treatment of the ...
(Date:3/28/2015)... Rocket Pure , a manufacturer of ... of their new natural sunscreen. They are offering the ... Both options come with a bonus lip balm sunscreen. , ... Amazon. Click to see the natural sunscreen on ... sunscreen is made with non-nano zinc oxide and provides broad-based ...
(Date:3/28/2015)... 2015 Could genetic code determine someone’s ... study by researchers at the Harvard T.H. Chan ... support of the Coffee and Caffeine Genetics Consortium and ... past fall, the study—one of several recent HSPH investigations ... from more than 120,000 regular coffee drinkers of European ...
(Date:3/28/2015)... March 28, 2015 Take a bite ... kicks into action. Acids tumble into the stomach, ready ... faulty valve-like structure lets these acids run amok, triggering ... extremely common symptom. More than 60 million Americans have ... examine where heartburn starts, and how it can be ...
(Date:3/28/2015)... New York, New York (PRWEB) March 28, 2015 ... ( http://www.vaginalmeshlawsuit2015.com/ ) involving devices manufactured by C.R. ... multidistrict litigation underway in U.S. District Court, Southern ... Jeffrey S. Grand, is serving on the Plaintiffs’ ... March 24th, the Court has granted certain defendants ...
Breaking Medicine News(10 mins):Health News:Rocket Pure Releases New Natural Sunscreens For Athletes 2Health News:Rocket Pure Releases New Natural Sunscreens For Athletes 3Health News:How Coffee Habits Relate to Our Genetic Code and Enhancing the Caffeine Experience 2Health News:How Coffee Habits Relate to Our Genetic Code and Enhancing the Caffeine Experience 3Health News:Bypass Your Heartburn Worries This Easter With Tylers Coffee 2Health News:Federal C.R. Bard Vaginal Mesh Lawsuits Move Forward, As Court Grants Defense Motion to Amend Responses to Master Complaint 2Health News:Federal C.R. Bard Vaginal Mesh Lawsuits Move Forward, As Court Grants Defense Motion to Amend Responses to Master Complaint 3Health News:Federal C.R. Bard Vaginal Mesh Lawsuits Move Forward, As Court Grants Defense Motion to Amend Responses to Master Complaint 4
... ... mount LED light fixtures improve energy savings, reduce carbon emissions and reduce maintenance costs. ... Quality tested and built to last. , ... Boulder, CO (PRWEB) June 15, 2010 -- Albeo Technologies, an ...
... One individual is ... and information resource, despite the floundering by past management. , ... Wilmington, DE (PRWEB) June 15, 2010 -- Scott Braddam, Editor ... the headaches that come with trying to reinvent the proverbial wheel. The previous management ...
... ... must be eliminated to stop the terrible human suffering and environmental toll exacted through ... difference. , ... June 15, 2010 -- Adrian Desbarats, owner of an organic clothing company ...
... ... a partnership agreement to provide an advanced paging solution for customers using BlackBerry® smartphones ... receive pages on their Blackberry smartphone via their current pager number and eliminate the ... ...
... certain PTSD symptoms may be key to treating anger among ... Carolina at Chapel Hill and Veterans Affairs researchers. ... or aggressiveness, but for the small subset who do, this ... PhD, lead author of the study, an assistant professor of ...
... shows that a simple, inexpensive and noninvasive carotid artery ultrasound ... tool for coronary artery disease (CAD). This may be an ... The ultrasound test can also be used to rule out ... pump function. The new study appears in the June ...
Cached Medicine News:Health News:Albeo Releases Six New Surface Mount LED Lighting Fixtures 2Health News:Albeo Releases Six New Surface Mount LED Lighting Fixtures 3Health News:Can New Management With An Old Name Help Bed Shoppers Forget the Past? 2Health News:Can New Management With An Old Name Help Bed Shoppers Forget the Past? 3Health News:Organic Clothing – Is Your Clothing Delivering Death in Small Doses? 2Health News:Organic Clothing – Is Your Clothing Delivering Death in Small Doses? 3Health News:Onset Technology and Citipage Ltd. Partner to Deliver Advanced Paging Messages to Smartphones 2Health News:Onset Technology and Citipage Ltd. Partner to Deliver Advanced Paging Messages to Smartphones 3Health News:Study: Specific PTSD symptoms related to anger and aggressiveness among Iraq/Afghanistan veterans 2Health News:Carotid artery ultrasound is an effective alternative to more invasive coronary angiography 2
(Date:3/27/2015)... March 27, 2015 /PRNewswire/ - Medicure Inc. (the "Company") ... has approved the grant of an aggregate of 236,070 ... and consultants of the Company pursuant to the Company,s ... to expire on the tenth anniversary of the date ... third anniversary of the date of grant and 50,000 ...
(Date:3/27/2015)... AUGUSTA, Ga. , March 27, 2015  Holographic ... innovator in the field of holographic medical imaging, is ... of its Kickstarter campaign. Launching on April 20 th ... Voxbox and Voxbox Pro. The 8-inch and 22-inch displays ... at home for the first time. In addition to ...
(Date:3/27/2015)... -- The Temple Health & Bioscience District (THBD) today announced ... 1802 South First St. in the Temple Medical and Education ... City of Temple to receive funding for redevelopment. ... Veterans Health Care System, the new facility will enable THBD ... and life science companies. Temple ...
Breaking Medicine Technology:Holographic Optical Technologies brings cutting-edge holograms to consumer market through upcoming Kickstarter campaign 2Holographic Optical Technologies brings cutting-edge holograms to consumer market through upcoming Kickstarter campaign 3Temple Health & Bioscience District Relocates, Offers Office And Lab Space To Biotech Companies 2
... – http://www.aubreyinc.com – announced that after a ... second generation product, AW BAT® Plus, it is ...  Founder Aubrey Woodroof, PhD MBA, expresses his appreciation for ... is a wonderful feeling to hear from a renowned ...
... of the Medicare Mobility Benefit has never been more ... Congress and regulators implemented policies and regulations limiting the ... senior citizens and people living with disabilities to obtain ... of changes ranging from the so-called competitive bidding program ...
Cached Medicine Technology:Aubrey Inc. Releases New Advanced Biosynthetic Wound Care Product 'AWBAT Plus' 2State of the Medicare Mobility Benefit 2State of the Medicare Mobility Benefit 3State of the Medicare Mobility Benefit 4State of the Medicare Mobility Benefit 5State of the Medicare Mobility Benefit 6
... thermometer that measures temperatures from -50 to ... easy-to-read display and minimum/maximum temperature memory. The ... with adhesive, by keyhole or flip-out desk ... is accurate to within 1C from -50 ...
... PVS allows the laboratory to verify automatic pipets ... the pipet. Each PVS kit contains six vials ... of Pipetting Solution. Using the pipet or dilutor ... titrations. The kit is then returned to Streck ...
... Concentrate is for use as a sheath ... Each 70ml bottle of Cytometry Concentrate dilutes ... water. Compared to Cubitainers, Streck Cytometry Concentrate ... saves money without compromising performance. Streck Cytometry ...
... storage and transport solution formulated ... cells in samples without reducing ... Samples treated with Cyto-Chex can ... seven days prior to analysis ...
Medicine Products: