Navigation Links
Scientists Spot Genetic Clues to Crohn's Disease
Date:8/27/2014

WEDNESDAY, Aug. 27, 2014 (HealthDay News) -- A new genetic discovery about Crohn's disease could lead to different ways to fight the bowel disorder, researchers report.

The scientists pinpointed chemical changes in Crohn's patients' DNA that affect how their genes work, and said these changes can be detected in blood samples.

Along with raising the possibility of a simple diagnostic test for Crohn's, the findings provide new insight into how the disease develops and suggest possible gene targets for new treatments, said the authors of the study. It was published Aug. 26 in the journal Inflammatory Bowel Diseases.

Previous research has found several genes linked to Crohn's, but not everyone who has the genes develops the condition.

The findings of this new study involving children with Crohn's disease in Scotland suggest that differences in environmental factors among people -- such as diet and gut bacteria -- can trigger Crohn's in some people with these genes, the researchers said.

In Scotland, the incidence of Crohn's has increased 500 percent in the past 50 years. Currently, there is no way to prevent Crohn's disease. Therapy focuses on treating symptoms, such as abdominal pain, diarrhea and severe weight loss.

"Our study gives the strongest evidence yet that epigenetic changes are involved in Crohn's disease. The findings provide a potential mechanism whereby diet or other environmental factors may modify genetic material to cause Crohn's disease," Jack Satsangi, of the Center for Genomic and Experimental Medicine at the University of Edinburgh, said in a university news release.

"We hope the findings will help to identify much-needed treatment opportunities for this debilitating condition," he concluded.

More information

The Crohn's & Colitis Foundation of America has more about Crohn's disease.

SOURCE: University of Edinburgh, news release, Aug. 26, 2014

--


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Scientists solving the mystery of human consciousness
2. Scientists uncover multiple faces of deadly breast cancer
3. Scientists identify major source of cells defense against oxidative stress
4. Scientists tailor cell surface targeting system to hit organelle ZIP codes
5. Scientists rewrite rulebook on breast cancer in landmark global study
6. Warwick scientists uncover how checkpoint proteins bind chromosomes
7. NIH scientists link quickly spreading gene to Asian MRSA epidemic
8. Joslin scientists identify important mechanism that affects the aging process
9. Scripps Research scientists show how memory B cells stay in class to fight different infections
10. Scientists Map Melanomas Genome
11. A*STAR scientists discover switch to boost anti-viral response to fight infectious diseases
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Spot Genetic Clues to Crohn's Disease
(Date:10/18/2018)... ... October 18, 2018 , ... Drummond Group, ... the Strategic Health Information Exchange Collaborative (SHIEC) as a Strategic Business and Technology ... , Drummond Group is a HITRUST CSF Assessor that assists HIEs to ...
(Date:10/18/2018)... ... October 18, 2018 , ... ... research study demonstrating the company’s automated preclinical image data analysis tool, InVivoAX™, ... The technology finds applications in preclinical imaging of small animal models of ...
(Date:10/16/2018)... ... 16, 2018 , ... CCC ( Compressor Controls Corporation ) ... today announces Total Train Comprehensive Release version 14.1 (TTCR 14.1), available for immediate ... on improving cybersecurity defense around turbomachinery. The upgrade process is seamless, without ...
(Date:10/16/2018)... (PRWEB) , ... October 16, 2018 , ... dicentra Global ... Cannabis Edibles HACCP Certification Program . Canada will become the first G7 country in ... the government of Canada also plans to formally legalize the production and use of ...
(Date:10/16/2018)... ... October 16, 2018 , ... AutismOne, ... host the proceedings of the 4th Annual International HPV Vaccine Education Symposium. , ... Wednesday, May 22, 2019, through Friday, May 24, 2019, with a keynote address ...
Breaking Medicine News(10 mins):
(Date:10/13/2018)... ... October 12, 2018 , ... Submissions to the ... from healthcare providers, students, trainees, and researchers worldwide. Winning proposals will receive grants ... and bioinformatics services. , “uBiome is thrilled to further expand our collaborations in ...
(Date:10/13/2018)... Manchester, UK (PRWEB) , ... October 13, 2018 , ... ... will reach 14.4 per cent over the next five years, from $3200 million in ... a key driver and could even help drive this growth further. This news comes ...
(Date:10/11/2018)... ... October 11, 2018 , ... ... announced today that it has completed the strategic combination of RevSpring and ... patient revenue cycle engagement, billing, and payments solutions generating over one billion ...
Breaking Medicine Technology: