Navigation Links
Scientists Spot DNA Linked With Dangerous Heart Rhythms
Date:12/27/2010

MONDAY, Dec. 27 (HealthDay News) -- Scientists have identified DNA sequence variations associated with abnormal heart rhythms that can cause heart damage and sudden death.

The international team studied nearly 50,000 people worldwide and found variants in 22 locations across the human genome that can effect QRS interval -- a measure of electrical depolarization in the heart's lower chambers (ventricles).

QRS interval is easily measured on an electrocardiogram (EKG). A prolonged QRS interval has been associated with increased risk for heart problems and sudden cardiac death.

Among the significant findings were variations in two side-by-side genes that regulate electrically charged particles to produce signals that activate heart contractions. One of these genes, SCN5A, is known to play a role in controlling how signals start from specialized muscle cells and travel across the heart to cause rhythmic contractions. It had not been known that the neighboring gene, SCN10A, played any role in cardiac electrical activity at all.

"The size of this study really gave us the power to identify many genes not previously suspected to play a role in heart conduction," corresponding author Dan Arking, an assistant professor at McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, said in a Hopkins news release.

The study was published recently in Nature Genetics.

More information

The U.S. National Heart, Lung, and Blood Institute has more about heart rhythm problems.

-- Robert Preidt

SOURCE: Johns Hopkins Medicine, news release, December 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Scientists Pinpoint Area of Brain That Fears Losing Money
2. Scientists Discover How HIV Is Transmitted Between Men
3. Prevention Is Key Research Goal for Premature Babies, Scientists Say
4. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
5. Scientists find donut-shaped structure of enzyme involved in energy metabolism
6. Neuroscientists reveal new links that regulate brain electrical activity
7. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. Scientists Spot Genetic Fingerprints of Individual Cancers
10. Scientists Unravel Mysteries of Intelligence
11. MSU scientists develop more effective method of predicting lead-poisoning risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Spot DNA Linked With Dangerous Heart Rhythms
(Date:5/31/2016)... ... , ... Spectrum Aquatics has launched a brand new ADA pool lift, the ... the user in mind. , “Over the last two years our key customers and ... lbs lift is a necessary requirement for certain facilities with specific needs,” said Nabil ...
(Date:5/31/2016)... ... May 31, 2016 , ... TeaZa® Energy, LLC ... pouches, on World No Tobacco Day . The new flavor—Tropical TeaZa? Energy—will ... on this summer. , The new flavor is best described as a juicy, ...
(Date:5/31/2016)... , ... May 31, 2016 , ... ... marketing services firm and statement solutions provider, for the tenth consecutive year ... May 2016 issue of Advertising Age, and SourceLink ranked eighteenth in the “U.S. ...
(Date:5/30/2016)... FL (PRWEB) , ... May 30, 2016 , ... As ... means for their children and their efforts to keep their households lice free. ... across Hawaii are enacting new policies that keep kids in the classroom despite the ...
(Date:5/30/2016)... , ... May 30, 2016 , ... Another ER facility ... in Plano, located at 3960 Legacy Drive, Plano, TX and is open 24 hours ... of Commerce followed by a medical open house. The Jasper High School band entertained ...
Breaking Medicine News(10 mins):
(Date:5/30/2016)... Eye expert s ... eye examination before leaving hospital ... Moorfields Eye Hospital Dubai, the first overseas branch of the ... identified premature babies as a special concern in the region when ... retinopathy of prematurity (ROP). ROP is a potentially blinding condition that ...
(Date:5/27/2016)... , May 27, 2016 ... innovative biopharmaceutical company focused on late-stage drug development, ... Dexcel Pharma of pivotal batches required for ... Drug Administration (FDA). This follows Kitov,s announcement ... III trial successfully met its primary efficacy endpoint. ...
(Date:5/26/2016)... , May 26, 2016 ... Associated With Both Cost Savings and Overall ... plc (LSE: BTG), an international specialist healthcare company, ... at the 21st Annual Meeting of ISPOR (International ... treatment of hepatocellular carcinoma (HCC) using yttrium-90 glass ...
Breaking Medicine Technology: