Navigation Links
Scientists Spot DNA Linked With Dangerous Heart Rhythms
Date:12/27/2010

MONDAY, Dec. 27 (HealthDay News) -- Scientists have identified DNA sequence variations associated with abnormal heart rhythms that can cause heart damage and sudden death.

The international team studied nearly 50,000 people worldwide and found variants in 22 locations across the human genome that can effect QRS interval -- a measure of electrical depolarization in the heart's lower chambers (ventricles).

QRS interval is easily measured on an electrocardiogram (EKG). A prolonged QRS interval has been associated with increased risk for heart problems and sudden cardiac death.

Among the significant findings were variations in two side-by-side genes that regulate electrically charged particles to produce signals that activate heart contractions. One of these genes, SCN5A, is known to play a role in controlling how signals start from specialized muscle cells and travel across the heart to cause rhythmic contractions. It had not been known that the neighboring gene, SCN10A, played any role in cardiac electrical activity at all.

"The size of this study really gave us the power to identify many genes not previously suspected to play a role in heart conduction," corresponding author Dan Arking, an assistant professor at McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, said in a Hopkins news release.

The study was published recently in Nature Genetics.

More information

The U.S. National Heart, Lung, and Blood Institute has more about heart rhythm problems.

-- Robert Preidt

SOURCE: Johns Hopkins Medicine, news release, December 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Scientists Pinpoint Area of Brain That Fears Losing Money
2. Scientists Discover How HIV Is Transmitted Between Men
3. Prevention Is Key Research Goal for Premature Babies, Scientists Say
4. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
5. Scientists find donut-shaped structure of enzyme involved in energy metabolism
6. Neuroscientists reveal new links that regulate brain electrical activity
7. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. Scientists Spot Genetic Fingerprints of Individual Cancers
10. Scientists Unravel Mysteries of Intelligence
11. MSU scientists develop more effective method of predicting lead-poisoning risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Spot DNA Linked With Dangerous Heart Rhythms
(Date:12/8/2016)... ... December 08, 2016 , ... Healthcare ... Act. Dr. Botelho advocates for the mass media launching of story movements to ... opportunities to share their unfortunate experiences; such a movement can generate the network ...
(Date:12/8/2016)... ... December 08, 2016 , ... Peter ... communities in and around the greater Phoenix metropolitan region, is announcing a charity ... The mission of the Homeless Youth Connection is to promote community awareness of ...
(Date:12/7/2016)... PA (PRWEB) , ... December 07, 2016 , ... ... with the announcement that it is one of the early adopters completing EU-U.S. Privacy ... Framework is designed to provide companies on both sides of the Atlantic with a ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... and deep lines by smoothing and tightening the skin of the face to ... to address facial aging with very little downtime, Silhouette Instalift is a novel, ...
(Date:12/7/2016)... Ca (PRWEB) , ... December 07, 2016 , ... It ... that funding is with useful, properly analyzed data. The team at Beckman Coulter has ... address the 'need for speed' and the need to operate in a GLP (Good ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... 7, 2016  Palatin Technologies, Inc. ("Palatin") (NYSE ... a previously disclosed underwritten public offering of units ... as sole book-running manager, Roth Capital Partners acted ... as co-manager for the offering. "This ... net proceeds, allowing us to continue advancing bremelanotide ...
(Date:12/7/2016)... , Dec. 7, 2016 DelveInsight,s, ... report provides in depth insights on the ... the Janus Kinase 3 (JAK3) Inhibitors. The ... various stages of development including Discovery, Pre-clinical, ... and Preregistration. Report covers the product clinical ...
(Date:12/7/2016)... YORK , Dec. 7, 2016 ... report on pulmonary drugs studies the current as ... The stakeholders of this report include companies and ... various pulmonary/respiratory drugs and/or drug-device combinations as well ... This report comprises an elaborate executive summary along ...
Breaking Medicine Technology: