Navigation Links
Scientists Reverse Multiple Sclerosis in Mice
Date:8/12/2009

Experimental treatment suppresses immune cells, forcing remission, study says,,

WEDNESDAY, Aug. 12 (HealthDay News) -- An experimental treatment that suppresses the immune system to put multiple sclerosis into remission completely reversed the disease in mice, Canadian scientists say.

In MS, the immune system attacks the central nervous system. The new treatment, called GIFT15, is composed of two proteins, GSM-CSF and interleukin-15, that are fused in the lab. Normally, the individual proteins act to stimulate the immune system, but when they're stuck together, the proteins suppress immune response, the researchers explained.

They do this by converting B-cells -- a type of white blood cell normally involved in immune response -- into immune suppressive cells.

"GIFT15 can take your normal, run-of-the-mill B-cells and convert them ... into these super-powerful B-regulatory cells," study team leader Dr. Jacques Galipeau, of the Jewish General Hospital Lady Davis Institute for Medical Research and McGill University in Montreal, said in a university news release.

He and his colleagues took normal B-cells from mice and sprinkled GIFT15 on the B-cells. "And when we gave them back intravenously to mice ill with multiple sclerosis, the disease went away," Galipeau said.

The treatment was fully effective with a single dose, and no significant side effects were seen in the mice, the researchers reported.

Their findings were published online Aug. 9 in Nature Medicine.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about multiple sclerosis.



-- Robert Preidt



SOURCE: McGill University, news release, Aug. 11, 2009
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Scientists Decode HIV Genome
2. 2009 American Association of Pharmaceutical Scientists Annual Meeting and Exposition
3. Scientists Learn How Cancer Drugs Cause Hypertension
4. Scientists Bioengineer New Teeth in Mice
5. Scientists ID First Human With Gorilla Strain of HIV
6. Scientists learn why even treated genital herpes sores boost the risk of HIV infection
7. UF scientists program blood stem cells to become vision cells
8. Scientists Find Way to Make Good Brown Fat
9. Scientists Test New Way to Get Drugs to Cancer Cells
10. Ethicon Endo-Surgery Holds Metabolic Surgery Scientific Forum Featuring Research By Top Scientists
11. Scientists Track Impact of DNA Damage in the Developing Brain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Reverse  Multiple Sclerosis in Mice
(Date:7/23/2014)... NJ (PRWEB) July 23, 2014 CarePoint ... the first hospital in New Jersey to receive the ... advanced robotics platform in the da Vinci series. This ... a profound step forward in innovation. The intuitive da ... across a wide spectrum of minimally invasive and complex ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 Ticket Down ... AS Roma tickets in Dallas, TX at the Cotton ... team tournament held in the United States and Canada beginning ... world including teams from La Liga, Serie A, English Premier ... are Manchester United, Manchester City, Olympiacos, Inter Milan, Liverpool, AS ...
(Date:7/23/2014)... American market was valued at $985.4 million in 2012. The ... to reach $1,801.1 million by 2018. Organobromines is the largest ... Market report defines and segments the bromine market in Europe ... TOC of the North American Bromine Market report, to get ... a glimpse of the segmentation in the North America bromine ...
(Date:7/23/2014)... July 23, 2014 This report defines ... Geography (Asia-Pacific, Europe, the Middle East & Africa, and ... systems and geography with analysis and forecasts of the ... to grow from over $10 billion in 2014 to ... over 5%. , browse 49 Market Tables and ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 Recently, Agebc.com ... . Now, the company is announcing a promotion of ... the promotion will end at the end of this ... in many popular styles, like A-line, mermaid, ball-gown, empire, ... wedding dresses and other special-occasion dresses for women, and ...
Breaking Medicine News(10 mins):Health News:CarePoint Health is First in New Jersey to Receive Newest Surgical Robot Platform 2Health News:CarePoint Health is First in New Jersey to Receive Newest Surgical Robot Platform 3Health News:CarePoint Health is First in New Jersey to Receive Newest Surgical Robot Platform 4Health News:Real Madrid vs. AS Roma Tickets Cotton Bowl Dallas, TX: Ticket Down Slashes Ticket Prices on all AS Roma vs. Real Madrid International Champions Cup Tickets 2Health News:Real Madrid vs. AS Roma Tickets Cotton Bowl Dallas, TX: Ticket Down Slashes Ticket Prices on all AS Roma vs. Real Madrid International Champions Cup Tickets 3Health News:North America Bromine Market is Expected to Reach $1801.1 million in 2018 - New Report by MicroMarket Monitor 2Health News:North America Bromine Market is Expected to Reach $1801.1 million in 2018 - New Report by MicroMarket Monitor 3Health News:North America Bromine Market is Expected to Reach $1801.1 million in 2018 - New Report by MicroMarket Monitor 4Health News:EHV Transmission Market $14 Billion by 2019 - Report by MarketsandMarkets 2Health News:EHV Transmission Market $14 Billion by 2019 - Report by MarketsandMarkets 3Health News:EHV Transmission Market $14 Billion by 2019 - Report by MarketsandMarkets 4Health News:Agebc.com Launched Its New Collection of Wedding Dresses 2
... FairWarning(R) announces 2007 achievements and foundation for ... 29 Today, FairWarning(R),announced 2007 company achievements ... further,the company,s position as the leading provider ... http://www.newscom.com/cgi-bin/prnh/20080128/FAIRWARNINGLOGO ), 2007 Growth ...
... DENVER, Jan. 29 HealthAware, a leading supplier ... launch of,WeightAware, the newest disease module in its ... with obesity and,arthritis. The program targets only those ... within 12 months., WeightAware is an extension ...
... name, company introduces new out-of-the-box proactive, ... ST. PETERSBURG, Fla., Jan. 29 EpicTide ... FairWarning(R). The company,s corporate,structure and mission remains unchanged. ... supplier of cross-platform privacy auditing,solutions for Electronic Health ...
... reported results include 22 percent sales growth and EPS of $.78, - Q4 pro forma adjusted results ... ... both sales and ... EPS, INDIANAPOLIS, Jan. 29 Eli Lilly and Company,(NYSE: LLY ) today announced ...
... Jan. 29 /Xinhua-PRNewswire-FirstCall/ -- China Medical,Technologies, Inc. ... leading China-based,medical device company that develops, manufactures ... high intensity focused ultrasound tumor,therapy systems, today ... results for the third quarter ended December ...
... CEO Bill Novelli,made the following statement today in ... (Logo: http://www.newscom.com/cgi-bin/prnh/20070209/NYF043LOGO ), "We ... us beyond,rhetoric and towards bipartisan solutions that are ... come together, openly,debate all available options, and solve ...
Cached Medicine News:Health News:FairWarning(R) Furthers Electronic Health Record Privacy Auditing Leadership 2Health News:HealthAware Introduces Its WeightAware Cardiovascular Disease Module 2Health News:EpicTide Changes Name to FairWarning(R) 2Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 2Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 3Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 4Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 5Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 6Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 7Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 8Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 9Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 10Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 11Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 12Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 13Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 14Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 15Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 16Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 17Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 18Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 19Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 20Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 21Health News:Lilly Caps Successful Year with Strong Fourth-Quarter Results 22Health News:China Medical Technologies to Announce Financial Results for the Third Quarter Ended December 31, 2007 on February 28, 2008 2Health News:Statement by AARP CEO Bill Novelli on President Bush's State of the Union 2
(Date:7/23/2014)...  Cardica, Inc. (Nasdaq: CRDC ) today announced ... quarter and year ended June 30, 2014, on Thursday, August ... a conference call at 4:30 p.m. Eastern Time to discuss ... business. Conference Call Details To access the live ... Time via phone, please dial 866-953-6859 from the ...
(Date:7/23/2014)... 2014  MiMedx Group, Inc.  (NASDAQ: ... of patent-protected regenerative biomaterials and bioimplants processed from ... its initial Investigational New Drug ("IND") application with ... The IND submission, which was filed yesterday, ... for certain indications of its micronized allografts towards ...
(Date:7/23/2014)... 23, 2014  ACON Equity Partners III, L.P., a ... ("ACON") announced it has completed the purchase of Injured ... Group and Parthenon Capital Partners. IWP is a leading ... Compensation, Automobile Personal Injury Protection and Personal Injury pharmacy ... As part of this transaction, ACON ...
Breaking Medicine Technology:Cardica to Announce Fiscal 2014 Fourth Quarter and Full Year Financial Results on Thursday, August 7, 2014 2MiMedx Files Its Initial Investigational New Drug Application 2MiMedx Files Its Initial Investigational New Drug Application 3ACON Investments Acquires Injured Workers Pharmacy 2ACON Investments Acquires Injured Workers Pharmacy 3
... from EAP in 2007, RICHMOND, Va., Jan. ... follow-on biologics and biopharmaceuticals, today,provided an update on ... the treatment of Amyotrophic Lateral Sclerosis (ALS). Since ... physicians and approximately 70 subjects,have been enrolled into ...
... Kind in US, Finds Allergy Immunotherapy ... Beneficial Even When Treatment Not Completed, MOSS ... health economics and outcomes research, today announced,findings of a ... benefits to children and significantly reduces health,care costs, even ...
Cached Medicine Technology:Insmed Provides Update on IPLEX(TM) Expanded Access Program in Italy for the Treatment of Amyotrophic Lateral Sclerosis 2Insmed Provides Update on IPLEX(TM) Expanded Access Program in Italy for the Treatment of Amyotrophic Lateral Sclerosis 3Study Says Allergy Shots Help Children, Reduce Health Care Costs 2Study Says Allergy Shots Help Children, Reduce Health Care Costs 3
The Cygnus-PFS Image-Guided Surgery System is the world's first portable and affordable image-guided surgery system....
Used for access and catheterization procedures. Double flexible tipped design permits alternative use of both ends of wire guide depending upon procedural needs. Supplied sterile in peel-open package...
The Emerald Guidewire is intended for percutaneous introduction of catheters....
Used to negotiate tortuous vessels....
Medicine Products: