Navigation Links
Scientists Probe Sepsis' Deadly Secrets
Date:8/18/2007

Inflammatory condition is 10th leading killer in United States, experts say

FRIDAY, Aug. 17 (HealthDay News) -- Even when they appear clinically similar, patients with potentially deadly sepsis may be having different kinds of immune responses, say U.S. researchers who conducted the first large-scale natural history study of the common condition.

Sepsis -- a result of the body's inflammatory response to infection -- can lead to organ failure and death. Almost one million people in the United States will develop sepsis this year, and about 30 percent will die, making it the 10th leading cause of death in the country.

The University of Pittsburgh team said its findings suggest that past interpretations of how the immune system responds to infection were incorrect, because they were based on data from small studies. As a result, most of the treatments based on those studies have proven ineffective.

For this study, the University of Pittsburgh team evaluated data from almost 1,900 patients hospitalized with community-acquired pneumonia (CAP), the leading cause of severe sepsis. More than 30 percent of the patients developed severe sepsis, and 26 percent of those patients died.

The researchers found that 82 percent of the CAP patients had elevated cytokine levels, which were highest among those with fatal severe sepsis and lowest among those with no sepsis. Cytokines are signaling proteins especially involved in immune and inflammatory processes.

The study was published this week in the journal Archives of Internal Medicine.

"Our data show that much of what we previously thought about the role of the inflammatory response plays in sepsis was wrong or incomplete," Dr. John A. Kellum, professor in the department of critical care at the University of Pittsburgh School of Medicine, said in a prepared statement.

"We had thought the inflammatory response to infection was relatively short-li
'/>"/>


Copyright©2007 ScoutNews,LLC.

Page: 1 2

Related medicine news :

1. Nobel Prize for Medicine shared by Three scientists
2. Scientists plan human cloning clinic in the United States
3. Scientists crack dengue fever puzzle
4. Scientists found ancient Human Germ Killer
5. Scientists locate key hormone involved in appetite control
6. Scientists open the book of life
7. Electronic nose by Italian scientists
8. Scientists review SARS
9. Scientists push to lower hidden sodium in food
10. Indian Scientists Make Wide-Ranging Analysis And Annotation Of X Chromosome
11. Scientists have found effective brain regions for deep brain stimulation for Parkinson’s
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... Catalent Pharma Solutions, the leading global ... for drugs, biologics and consumer health products, has ... and technology offer based on the company’s expertise ... 450,000 sq. ft. Kansas City, MO facility. , ... formulation, development, analytical expertise, scale up and manufacturing ...
(Date:9/17/2014)... JOLLA, CASeptember 17, 2014Scientists at The Scripps Research ... on vancomycin that is powerfully effective against vancomycin-resistant ... The new vancomycin analog appears to have not ... against which bacteria probably cannot evolve resistance quickly. ... once introduced will still be in clinical use ...
(Date:9/17/2014)... 17, 2014 Boston Children’s Museum ... a monthly concert series, introducing young Museum visitors ... Top, America’s premier national platform celebrating the stories, ... of the young musicians featured will also be ... Children’s Museum is fortunate to partner with the ...
(Date:9/17/2014)... A petition to ban the use of ... other gynecological surgeries has gathered nearly 85,000 signatures, Bernstein ... at least 84,908 supporters had signed the petition as ... report from ABC News, the Change.org petition was launched ... his wife, Dr. Amy Reed, was diagnosed with Stage ...
(Date:9/17/2014)... WEDNESDAY, Sept. 17, 2014 (HealthDay News) -- Present-day ... groups of ancient humans, according to a new ... descended from indigenous hunter-gatherers and early European farmers. ... samples revealed they are also the descendants of ... genetic material from this third ancestral group, researchers ...
Breaking Medicine News(10 mins):Health News:New OptiPact™ Technology Introduced by Catalent 2Health News:Scripps Research Institute chemists modify antibiotic to vanquish resistant bacteria 2Health News:Scripps Research Institute chemists modify antibiotic to vanquish resistant bacteria 3Health News:Boston Children's Museum Partners with From the Top to Offer Monthly Concert Series 2Health News:Boston Children's Museum Partners with From the Top to Offer Monthly Concert Series 3Health News:Power Morcellator Petition Nears 85,000 Signatures, Bernstein Liebhard LLP Reports 2Health News:Power Morcellator Petition Nears 85,000 Signatures, Bernstein Liebhard LLP Reports 3Health News:Power Morcellator Petition Nears 85,000 Signatures, Bernstein Liebhard LLP Reports 4Health News:Europeans Are Descendants of at Least 3 Ancient Human Groups: Study 2Health News:Europeans Are Descendants of at Least 3 Ancient Human Groups: Study 3
... Pancreatic cancer develops and spreads much more slowly than ... Hopkins investigators. The finding indicates that there is a ... disease. "For the first time, we have a ... when it would be best to intervene," according to ...
... tumors are one of the most lethal cancers, with fewer ... But a new study that peers deeply into the genetics ... opportunity for early diagnosis. In contrast to earlier predictions, many ... years to become lethal after the first genetic perturbations appear. ...
... PHILADELPHIA Demetrius H. Bagley, M.D., the Nathan Lewis Hatfield ... Medical College (JMC) of Thomas Jefferson University was recently honored ... Award in Endourology at the World Congress of Endourology. ... is fitting that Dr. Bagley was chosen to receive the ...
... News) --Mental health issues confronted by U.S. veterans returning ... by gender, new research suggests. Female veterans ... than are their male counterparts, according to a study ... the Veterans Administration from 2002 to 2008. They are ...
... efficient as humans mature. Now, for the first time ... Polytechnique Fdrale de Lausanne (EPFL) and the University of ... verified these gains with a powerful new computer program. ... the soon-to-be-released software allows for individualized maps of vital ...
... and University of North Carolina (UNC) researchers report in ... that narcotics and diagnostic testing are overused in ... overlook more effective treatments for neck pain, such as ... evidence to support the effectiveness of therapeutic exercise in ...
Cached Medicine News:Health News:Surprise finding: Pancreatic cancers progress to lethal stage slowly 2Health News:Surprise finding: Pancreatic cancers progress to lethal stage slowly 3Health News:Revising the timeline for deadly pancreatic cancer 2Health News:Revising the timeline for deadly pancreatic cancer 3Health News:Jefferson urologist awarded Lifetime Achievement Award from Endourological Society 2Health News:Mental Health Issues Differ for U.S. Male, Female Vets 2Health News:The brain's journey from early Internet to modern-day fiber optics -- all in 1 lifetime 2Health News:Narcotics and diagnostics overused in treatment of chronic neck pain 2
(Date:9/17/2014)... NEW YORK , Sept. 17, 2014 ... on behalf of purchasers of the securities of PDL ... PDLI -News).  Such investors are advised to ... coordinator Eitan Kimelman at info@bgandg.com ... the Company and certain of its executives violated federal ...
(Date:9/17/2014)... EDEN PRAIRIE, Minn. , Sept. 17, 2014 /PRNewswire/ ... pioneer and global market leader of advanced imaging modalities ... Intravascular Ultrasound System in two live cases at the ... The cases were presented from Medstar Washington ... New York-Presbyterian Hospital/Columbia University Medical Center ( New ...
(Date:9/17/2014)... DALLAS , Sept. 17, 2014   OTEMR, ... 2014 Edition Complete EHR certification, which designates that the ... the Stage 1 and Stage 2 Meaningful Use measures ... and Reinvestment Act (ARRA).  ONETOUCH EMR 2.0 was certified ... an Office of the National Coordinator-Authorized Certification Body (ONC-ACB) ...
Breaking Medicine Technology:Shareholder Alert: Bronstein, Gewirtz & Grossman, LLC Investigates claims on behalf of Investors of PDL BioPharma, Inc. --PDLI 2ACIST Launches HDi High-Definition IVUS 2ACIST Launches HDi High-Definition IVUS 3OTEMR, Inc.'s ONETOUCH EMR Achieves ONC HIT 2014 Edition COMPLETE EHR Certification from ICSA Labs 2OTEMR, Inc.'s ONETOUCH EMR Achieves ONC HIT 2014 Edition COMPLETE EHR Certification from ICSA Labs 3
... speed and efficiency in the healthcare process remains ... essential variables to ensure healthy, accurate outcomes. Rising ... Align Networks, a physical medicine provider network, have ... pace of healthcare. (Logo:   http://photos.prnewswire.com/prnh/20080206/AQW030LOGO-b ...
... Cynosure, Inc. (Nasdaq: CYNO ), ... array of light-based aesthetic treatment systems, today announced ... financial results before the market opens on Tuesday, ... investors and analysts that day at 9:00 a.m. ...
Cached Medicine Technology:Realizing Healthcare Savings Using Real-Time Technology 2Realizing Healthcare Savings Using Real-Time Technology 3Cynosure to Host Third-Quarter 2010 Financial Results Conference Call on October 26 2
This 100 µL is the equivalent to the "Universal Blue" tips and fits virtually every manufacturer's 1000 µL Pipettor....
Conducting disposable tips provide cross-contaminationfree pipetting for sensitive applications such as PCR setup....
Volume range 0.2-10 l. Designed for pipetting micro-sized drops. Ideal for use with micro volume Finnpipettes....
Conducting disposable tips....
Medicine Products: