Navigation Links
Scientists Pinpoint Most Major Genes Behind Deadly Blood Cancer
Date:5/1/2013

WEDNESDAY, May 1 (HealthDay News) -- Nearly all the genetic mutations associated with the blood cancer acute myeloid leukemia (AML) have probably been identified, researchers report.

The findings could lead to improved treatments for AML patients, as well as ways to more accurately predict the severity of disease in individual patients. AML is a fast-growing cancer that often is difficult to treat.

"We now have a genetic playbook for this type of leukemia," study co-leader Dr. Timothy Ley, associate director for cancer genomics at the Genome Institute at Washington University School of Medicine in St. Louis, said in a university news release.

"We don't know all the rules yet, but we know all the major players," Ley said. "This information can help us begin to understand which patients need more aggressive treatment right up front, and which can be treated effectively with standard chemotherapy."

The study included about 200 AML patients. Ley and his colleagues analyzed the DNA of each patient's leukemia cells and compared it to DNA from their healthy cells. Doing so enabled the researchers to pinpoint the mutations that occurred only in the cancer cells and contributed to the development and progression of AML.

Cancer cells in the AML patients had an average of 13 mutated genes, far fewer than the several hundred typically found in breast, lung and other solid tumors, according to the study, which was published online May 1 in The New England Journal of Medicine.

Because the study included a large number of AML patients, the researchers believe they have found nearly all of the major mutations linked with the disease.

Nearly 15,000 Americans will be diagnosed with AML this year, and more than 10,000 will die from the disease.

More information

The American Cancer Society has more about acute myeloid leukemia.

-- Robert Preidt

SOURCE: Washington University School of Medicine, news release, May 1, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Temple scientists weaken HIV infection in immune cells using synthetic agents
2. HIV Cure Looks Promising, Danish Scientists Contend
3. Guelph scientists develop first vaccine to help control autism symptoms
4. Scientists Spot Cancer Metabolism Changes
5. Work By Female Scientists Gets Judged More Harshly: Study
6. Scientists May Have Spotted Brains Numbers Center
7. Scientists scan the human heart to create digital anatomical library
8. Scientists Create Breast Cancer Survival Predictor
9. Molecule treats leukemia by preventing cancer cell repair, Jackson Laboratory scientists report
10. Scientists map elusive 3-D structure of telomerase enzyme, key actor in cancer, aging
11. Scientists discover gene mutation that causes children to be born without spleen
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Pinpoint Most Major Genes Behind Deadly Blood Cancer
(Date:10/13/2017)... ... 2017 , ... Lori R. Somekh, founder of the Law Office of ... elder law and special needs planning attorneys. “Membership in ElderCounsel helps our office remain ... to network with elder law attorneys nationwide,” said Somekh. , ElderCounsel ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term ... long-term care insurance companies have a waiver for care if the client has a ... when the family pays for care, is often waived, so the benefits from their ...
(Date:10/13/2017)... ... ... Ellevate Network, the leading network for professional women, brought together some of ... their inaugural Summit in New York City in June. The event was livestreamed with ... 3 million. To watch the Mobilize Women video, click here . , ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... the most popular and least understood books in the Holy Scriptures, Revelation. The Book ... have baffled scholars for centuries. Many have tossed it off as mere rubbish, but ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, ... Development, has been awarded a contract by the Center for Medicare and Medicaid ... to accelerate the enterprise use of Agile methodologies in a consistent and high ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... 2017  South Korean-based healthcare product Development Company I.M. ... on Kickstarter. The device will educate the user about ... better efficiency compared to the dated and pricey CPR ... efficacy of the compression for a more informed CPR ... to raise $5,000. ...
(Date:10/2/2017)... Mich. , Oct. 2, 2017 Diplomat ... 8th Day Software and Consulting, LLC , and ... 8th Day Software, based in Tennessee ... LLC. 8th Day expands EnvoyHealth,s service offerings for health ... development. "In an ...
(Date:10/2/2017)... 2017 Halo Labs announces the European launch of their ... HORIZON at MIBio 2017 in Cambridge, U.K ... matter in biopharmaceutical samples with unprecedented speed and sensitivity while using ... Backgrounded Membrane Imaging. ... subvisible particle analysis system ...
Breaking Medicine Technology: