Navigation Links
Scientists Pinpoint Most Major Genes Behind Deadly Blood Cancer
Date:5/1/2013

WEDNESDAY, May 1 (HealthDay News) -- Nearly all the genetic mutations associated with the blood cancer acute myeloid leukemia (AML) have probably been identified, researchers report.

The findings could lead to improved treatments for AML patients, as well as ways to more accurately predict the severity of disease in individual patients. AML is a fast-growing cancer that often is difficult to treat.

"We now have a genetic playbook for this type of leukemia," study co-leader Dr. Timothy Ley, associate director for cancer genomics at the Genome Institute at Washington University School of Medicine in St. Louis, said in a university news release.

"We don't know all the rules yet, but we know all the major players," Ley said. "This information can help us begin to understand which patients need more aggressive treatment right up front, and which can be treated effectively with standard chemotherapy."

The study included about 200 AML patients. Ley and his colleagues analyzed the DNA of each patient's leukemia cells and compared it to DNA from their healthy cells. Doing so enabled the researchers to pinpoint the mutations that occurred only in the cancer cells and contributed to the development and progression of AML.

Cancer cells in the AML patients had an average of 13 mutated genes, far fewer than the several hundred typically found in breast, lung and other solid tumors, according to the study, which was published online May 1 in The New England Journal of Medicine.

Because the study included a large number of AML patients, the researchers believe they have found nearly all of the major mutations linked with the disease.

Nearly 15,000 Americans will be diagnosed with AML this year, and more than 10,000 will die from the disease.

More information

The American Cancer Society has more about acute myeloid leukemia.

-- Robert Preidt

SOURCE: Washington University School of Medicine, news release, May 1, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Temple scientists weaken HIV infection in immune cells using synthetic agents
2. HIV Cure Looks Promising, Danish Scientists Contend
3. Guelph scientists develop first vaccine to help control autism symptoms
4. Scientists Spot Cancer Metabolism Changes
5. Work By Female Scientists Gets Judged More Harshly: Study
6. Scientists May Have Spotted Brains Numbers Center
7. Scientists scan the human heart to create digital anatomical library
8. Scientists Create Breast Cancer Survival Predictor
9. Molecule treats leukemia by preventing cancer cell repair, Jackson Laboratory scientists report
10. Scientists map elusive 3-D structure of telomerase enzyme, key actor in cancer, aging
11. Scientists discover gene mutation that causes children to be born without spleen
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Pinpoint Most Major Genes Behind Deadly Blood Cancer
(Date:6/23/2017)... ... June 23, 2017 , ... 21 Middle East and ... has selected 21 leaders from government, business and civil society in 11 countries across ... U.S. this fall, engaging in a transformative exchange of knowledge and ideas with the ...
(Date:6/23/2017)... Jupiter, FL (PRWEB) , ... June 23, 2017 , ... ... the award winning series, which is slated to air fourth quarter 2017. American Farmer ... Christian D.A. Hansen, a Danish pharmacist, founded Chr. Hansen in Denmark in 1874 ...
(Date:6/23/2017)... ... June 23, 2017 , ... All-Star Insurance, a family managed agency that ... eastern Texas, is announcing the launch of a new charity drive to benefit women ... the United States reveal that an estimated 252, 710 new cases of invasive or ...
(Date:6/22/2017)... ... June 22, 2017 , ... Plastic Surgery Associates is proud to report that ... Each year, research and information firm, Castle Connolly, releases their list of the most ... marks the 3rd time that Dr. Canales has been recognized by Castle ...
(Date:6/22/2017)... ... 2017 , ... Despite its pervasiveness, many physicians are unfamiliar with how best ... with clinical practice. Now, however, a timely review has been published in the ... etiology of NeuP and educating preclinical scientists on its diagnosis and choice of treatment. ...
Breaking Medicine News(10 mins):
(Date:6/12/2017)... 12, 2017 Kineta, Inc., a biotechnology company focused ... Vice President of R&D and Head of Virology Kristin ... Preparedness for the Northwest and Beyond meeting sponsored by ... 14, 2017 from 8:30-10:30 AM PDT at the Agora Conference ... Dr. Bedard will be joined by other leaders in ...
(Date:6/9/2017)... ALTO, Calif. , June 9, 2017 ... device company focused on the design, manufacture, sale and ... the market on the progress of its commercial roll-out ... is now available in more than one hundred (100) ... AeroForm offers a needle-free alternative for ...
(Date:6/8/2017)... 2017   Responding to Heath Ledger,s father,s ... of singer Chris Cornell in May, the mental ... a free online psychiatric drug side effects ... about psychotropic drug risks. The father of ... an accidental overdose, has called for tighter rules on prescription ...
Breaking Medicine Technology: