Navigation Links
Scientists Map Elephantiasis Parasite's Genome

Achievement should help fight the disfiguring disease

THURSDAY, Sept. 20 (HealthDay News) -- An international team of scientists says they've documented the genetic sequence of one of the world's most debilitating human parasites.

Microscopic Brugia malayi worms can live for years inside the human body. The parasite can be transmitted through the bites of infected insects or spiders, noted researchers reporting in the Sept. 21 issue of the journal Science.

Infection with B. malayi can lead to a disfiguring disease called elephantiasis, which features an excessive buildup of lymphatic fluid in the body and extreme swelling in the limbs, trunk or head. It's estimated that B. malayi has seriously incapacitated and disfigured more than 40 million people worldwide, according to the World Health Organization.

The researchers said the genetic sequence of B. malayi reveals dozens of potential new targets for drugs or vaccines to understand, treat and prevent elephantiasis.

"The genomic information gives us a better understanding of what genes are important for different processes in the parasite's life cycle. So, it will now be possible to target these genes more specifically and interrupt its life cycle," study first author Elodie Ghedin, assistant professor of infectious diseases at the University of Pittsburgh School of Medicine, said in a prepared statement.

Current drugs target the larvae but don't completely kill the worms. Often, patients must take drugs periodically for years. When a worm does die, it can release foreign molecules into the body that cause a major immune reaction.

More information

The World Health Organization has more about elephantiasis.

-- Robert Preidt

SOURCE: University of Pittsburgh Schools of Health Sciences, news release, Sept. 20, 2007

Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Nobel Prize for Medicine shared by Three scientists
2. Scientists plan human cloning clinic in the United States
3. Scientists crack mechanism of Leptin-Obesity Hormone
4. Scientists use plant hormones to fight cancer
5. American scientists alter gene makeup of babies
6. Expose on eating disorders!! Scientists trace “brain’s eating control center pathway”
7. Scientists found ancient Human Germ Killer
8. Scientists locate key hormone involved in appetite control
9. Scientists open the book of life
10. Electronic nose by Italian scientists
11. Scientists review SARS
Post Your Comments:
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, ... at Work award to iHire in recognition of their exemplary accomplishments in worksite health ... annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is ... associated with chronic pain and the benefits of holistic treatments, Serenity Recovery Center ... suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. The ... published in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , ...
(Date:6/24/2016)... ... ... National recruitment firm Slone Partners is pleased to announce the placement of ... President of North American Capital Sales at HTG Molecular . , ... the commercialization of the HTG EdgeSeq system and associated reagents in North America. , ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Calif. , June 23, 2016 Any dentist ... many challenges of the current process. Many of them do ... of the technical difficulties and high laboratory costs involved. And ... to offer it at such a high cost that the ... it. Dr. Parsa Zadeh , founder of ...
(Date:6/23/2016)... -- Research and Markets has announced the addition ... - Forecast to 2022" report to their offering. ... to date financial data derived from varied research sources to ... potential impact on the market during the next five years, ... of sub markets, regional and country level analysis. The report ...
(Date:6/23/2016)... , June 23, 2016 , ... Thursday, July 7, 2016 , , , , LOCATION: , ... , , , , EXPERT PANELISTS:  , , , Frost ... Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh ... The global pharmaceutical industry is witnessing an exceptional era. Several ...
Breaking Medicine Technology: