Navigation Links
Scientists Link More Genes to Common Brain Tumor
Date:1/24/2013

THURSDAY, Jan. 24 (HealthDay News) -- Abnormalities in just five genes account for the majority of meningioma brain tumors, according to a new study.

Meningiomas are the most common type of brain tumor. They are usually benign but are cancerous in about 10 percent of cases. Surgery is the only treatment for meningiomas, but this finding could help lead to new therapies tailored to individual patients, according to the study authors.

Previous research found that about half of meningiomas were linked to a mutation or deletion of a gene called neurofibromin 2. The genetic origin of the other types of meningiomas was unknown.

In this study, researchers analyzed samples from 300 meningiomas and found that abnormalities in four other genes are also linked to the brain tumors. Each of these genes tends to be associated with tumors in different areas of the brain. Location can indicate how likely meningiomas are to become cancerous.

The study was published online Jan. 24 in the journal Science.

"Combining knowledge of these mutations with the location of tumor growth has direct clinical relevance and opens the door for personalized therapies," study senior author Murat Gunel, a professor of neurosurgery, genetics and neurobiology at Yale University School of Medicine in New Haven, Conn., said in a university news release. Gunel is also a member of Yale Cancer Center's genetics and genomics research program.

Personalized therapies could include treating some patients with chemotherapy only or sparing vulnerable patients from radiation therapy, according to the release.

More information

The American Brain Tumor Association has more about meningiomas.

-- Robert Preidt

SOURCE: Yale University, news release, Jan. 24, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Temple scientists find cancer-causing virus in the brain, potential connection to epilepsy
2. Scientists identify new strategy to fight deadly infection in cystic fibrosis
3. Social Scientists call for more effective teaching in Higher Education
4. UT MD Anderson scientists find protein that reins in runaway network
5. Study Finds Older Male Scientists Likelier to Commit Research Fraud
6. NIH scientists identify protective role for antibodies in Ebola vaccine study
7. Johns Hopkins neuroscientists win National Academy of Science Awards
8. Scientists find a new way to boost common cancer drugs
9. Cancer scientists determine mechanism of 1 of the most powerful tumor-suppressor proteins, Chd5
10. New American Chemical Society video series: Conversations with Celebrated Scientists
11. Scientists discover how deadly skin cancer spreads into other parts of the body
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Link More Genes to Common Brain Tumor
(Date:4/26/2017)... ... April 26, 2017 , ... RawTrition now brings you BioEnergy which is ... from SUPERFOODS! , RawTrition is taking nutrients to the next level! ... body recognizes its raw form (unlike the synthetically made options that are on the ...
(Date:4/25/2017)... , ... April 25, 2017 , ... ... breakthrough topical cream that’s the first in a new class of photodynamic cosmetics ... overall appearance of skin, visibly reduce outward signs of aging, and minimize the ...
(Date:4/25/2017)... ... 2017 , ... As President Trump challenges the status quo ... administration could impact the employee benefits industry. James Slotnick, AVP, Government Relations, for ... make it through Congress. His discussion will focus on the current state of ...
(Date:4/25/2017)... (PRWEB) , ... April 25, 2017 , ... ... targets, they rely on contracted partners to help with process innovation in drug ... combined drug formulation experience along with state-of-the-art analytical equipment in support of their ...
(Date:4/25/2017)... (PRWEB) , ... April 25, 2017 , ... ... addition of predictive analytics to its patient care management module. Using this new ... before a patient has been initiated on continuous positive airway pressure (CPAP), oral, ...
Breaking Medicine News(10 mins):
(Date:4/18/2017)... , April 18, 2017  Cardinal Health (NYSE: ... fiscal 2017 earnings per share (EPS) guidance and ... This is in conjunction with this morning,s announcement of ... Thrombosis and Nutritional Insufficiency businesses. Cardinal Health ... operations will be at the bottom of its previous ...
(Date:4/18/2017)... DALLAS , April 18, 2017 Viverae ... proud to announce the integration of IBM ® ... platform to deliver targeted communications for a personalized experience. ... meaningful actions on their health in real time. The ... that matter most to members, wherever they are in ...
(Date:4/18/2017)... DIEGO , April 18, 2017  Astute Medical, ... a case series to be presented at the 2017 ... which begins today and continues through April 22. Physicians ... IGFBP-7 , used to assess risk for acute kidney ... decompensated heart failure (ADHF). Elevated levels ...
Breaking Medicine Technology: