Navigation Links
Scientists Link More Genes to Common Brain Tumor

THURSDAY, Jan. 24 (HealthDay News) -- Abnormalities in just five genes account for the majority of meningioma brain tumors, according to a new study.

Meningiomas are the most common type of brain tumor. They are usually benign but are cancerous in about 10 percent of cases. Surgery is the only treatment for meningiomas, but this finding could help lead to new therapies tailored to individual patients, according to the study authors.

Previous research found that about half of meningiomas were linked to a mutation or deletion of a gene called neurofibromin 2. The genetic origin of the other types of meningiomas was unknown.

In this study, researchers analyzed samples from 300 meningiomas and found that abnormalities in four other genes are also linked to the brain tumors. Each of these genes tends to be associated with tumors in different areas of the brain. Location can indicate how likely meningiomas are to become cancerous.

The study was published online Jan. 24 in the journal Science.

"Combining knowledge of these mutations with the location of tumor growth has direct clinical relevance and opens the door for personalized therapies," study senior author Murat Gunel, a professor of neurosurgery, genetics and neurobiology at Yale University School of Medicine in New Haven, Conn., said in a university news release. Gunel is also a member of Yale Cancer Center's genetics and genomics research program.

Personalized therapies could include treating some patients with chemotherapy only or sparing vulnerable patients from radiation therapy, according to the release.

More information

The American Brain Tumor Association has more about meningiomas.

-- Robert Preidt

SOURCE: Yale University, news release, Jan. 24, 2013

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Temple scientists find cancer-causing virus in the brain, potential connection to epilepsy
2. Scientists identify new strategy to fight deadly infection in cystic fibrosis
3. Social Scientists call for more effective teaching in Higher Education
4. UT MD Anderson scientists find protein that reins in runaway network
5. Study Finds Older Male Scientists Likelier to Commit Research Fraud
6. NIH scientists identify protective role for antibodies in Ebola vaccine study
7. Johns Hopkins neuroscientists win National Academy of Science Awards
8. Scientists find a new way to boost common cancer drugs
9. Cancer scientists determine mechanism of 1 of the most powerful tumor-suppressor proteins, Chd5
10. New American Chemical Society video series: Conversations with Celebrated Scientists
11. Scientists discover how deadly skin cancer spreads into other parts of the body
Post Your Comments:
Related Image:
Scientists Link More Genes to Common Brain Tumor
(Date:10/13/2017)... Worth, TX (PRWEB) , ... October 13, 2017 ... ... financial planning agency serving communities in the greater Dallas, Miami, and Raleigh regions, ... young boy fighting to overcome a rare and deadly chromosome abnormality. , After ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... certification process to promote standards of excellence for the field of eating disorders, ... March 22 – 25, 2018 in Orlando, Florida at the Omni Resort at ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that covers ... companies have a waiver for care if the client has a cognitive impairment diagnosis. ... pays for care, is often waived, so the benefits from their insurance start immediately,” ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... giving viewers the lowdown on sciatica in a new episode of "Success Files," ... on current events and innovation and investigates each subject in-depth with passion and ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and ... apnea using cutting-edge Oventus O2Vent technology. As many as 18 million Americans ... frequent cessation in breathing. Oral appliances can offer significant relief to about 75 ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... OBP Medical , a leading ... today announced regulatory approval from Brazil,s ... Nacional de Vigilância Sanitária (ANVISA)) to market ... with integrated LED light source and smoke evacuation ... of a tissue pocket or cavity during surgical ...
(Date:10/2/2017)... -- AllianceRx Walgreens Prime, the combined central specialty pharmacy and ... manager Prime Therapeutics LLC (Prime), today officially began the ... of new signage at its headquarters in ... few other company-owned facilities across the country. This also ... whom will begin to see the AllianceRx Walgreens Prime ...
(Date:9/28/2017)... 28, 2017 Hill-Rom Holdings, Inc. (NYSE: HRC), ... call and webcast on Friday, November 3, 2017, beginning ... ending at approximately 8:30 a.m. (CDT) / 9:30 a.m. ... 2017 financial performance and guidance for 2018, Hill-Rom executives ... enhance operational performance, and long-range financial outlook through 2020. ...
Breaking Medicine Technology: