Navigation Links
Scientists Link More Genes to Common Brain Tumor

THURSDAY, Jan. 24 (HealthDay News) -- Abnormalities in just five genes account for the majority of meningioma brain tumors, according to a new study.

Meningiomas are the most common type of brain tumor. They are usually benign but are cancerous in about 10 percent of cases. Surgery is the only treatment for meningiomas, but this finding could help lead to new therapies tailored to individual patients, according to the study authors.

Previous research found that about half of meningiomas were linked to a mutation or deletion of a gene called neurofibromin 2. The genetic origin of the other types of meningiomas was unknown.

In this study, researchers analyzed samples from 300 meningiomas and found that abnormalities in four other genes are also linked to the brain tumors. Each of these genes tends to be associated with tumors in different areas of the brain. Location can indicate how likely meningiomas are to become cancerous.

The study was published online Jan. 24 in the journal Science.

"Combining knowledge of these mutations with the location of tumor growth has direct clinical relevance and opens the door for personalized therapies," study senior author Murat Gunel, a professor of neurosurgery, genetics and neurobiology at Yale University School of Medicine in New Haven, Conn., said in a university news release. Gunel is also a member of Yale Cancer Center's genetics and genomics research program.

Personalized therapies could include treating some patients with chemotherapy only or sparing vulnerable patients from radiation therapy, according to the release.

More information

The American Brain Tumor Association has more about meningiomas.

-- Robert Preidt

SOURCE: Yale University, news release, Jan. 24, 2013

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Temple scientists find cancer-causing virus in the brain, potential connection to epilepsy
2. Scientists identify new strategy to fight deadly infection in cystic fibrosis
3. Social Scientists call for more effective teaching in Higher Education
4. UT MD Anderson scientists find protein that reins in runaway network
5. Study Finds Older Male Scientists Likelier to Commit Research Fraud
6. NIH scientists identify protective role for antibodies in Ebola vaccine study
7. Johns Hopkins neuroscientists win National Academy of Science Awards
8. Scientists find a new way to boost common cancer drugs
9. Cancer scientists determine mechanism of 1 of the most powerful tumor-suppressor proteins, Chd5
10. New American Chemical Society video series: Conversations with Celebrated Scientists
11. Scientists discover how deadly skin cancer spreads into other parts of the body
Post Your Comments:
Related Image:
Scientists Link More Genes to Common Brain Tumor
(Date:11/27/2015)... CA (PRWEB) , ... November 27, 2015 , ... According ... at the recent 2015 American Dental Association meeting in Washington D.C. revolved around the ... protect a patient’s overall health. The talk stressed the link between periodontal disease (more ...
(Date:11/27/2015)... ... November 27, 2015 , ... The ... in America. As people age, more care is needed, especially with Alzheimer’s, dementia ... medical professionals are being overworked. The forgotten part of this equation: 80 percent ...
(Date:11/27/2015)... ... November 27, 2015 , ... "When I was traveling, ... from Hillside, N.J. "Many people catch diseases simply from sitting on such dirty ... be protected from germs." , He developed the patent-pending QUDRATECS to eliminate the ...
(Date:11/27/2015)... ... 27, 2015 , ... ProSidebar: Fashion is a set of 30 ... ProSidebar: Fasion, video editors can easily add an informative sidebar to any FCPX production. ... Utilize presets featuring self-animating drop zones, lines, bars, and text with the ease of ...
(Date:11/27/2015)... ... November 27, 2015 , ... Intellitec ... Dynamics SL User Group (MSDSLUG). Recognized as Microsoft’s official group for end users ... Dynamics SL software users, partners, industry experts and representatives. Intellitec Solutions’ membership status ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , Nov. 26, 2015 Research ... addition of the "2016 Future Horizons and ... (TDM) Market: Supplier Shares, Country Segment Forecasts, Competitive ... --> --> ... analysis of the Italian therapeutic drug monitoring market, ...
(Date:11/25/2015)... 25, 2015 ... the "Global Brain Monitoring Devices Market ... --> ) has announced the ... Devices Market 2015-2019" report to their ... ( ) has announced the addition ...
(Date:11/25/2015)... 25, 2015  The American Academy of Pediatrics ... and the March of Dimes cheered today,s signature ... Infants Act of 2015 (S.799), which takes ... born exposed to drugs, such as opioids, and ... all three organizations have worked together leading advocacy ...
Breaking Medicine Technology: