Navigation Links
Scientists ID Uterine Muscle Switch for Contractions
Date:11/21/2008

Finding may lead to new therapies for preterm labor

FRIDAY, Nov. 21 (HealthDay News) -- Researchers say they've found the switch that activates the uterine muscles for contraction during childbirth, a finding that may lead to therapies for preterm labor.

The molecule prostacyclin normally binds the protein IP on the surface of these uterine muscle cells, keeping them relatively inactive during pregnancy.

But researchers from Dartmouth Medical School in New Hampshire, testing uterine tissue strips from pregnant women undergoing Caesarean birth, found that agonist chemicals can stimulate IP, which then activated proteins involved in muscle contraction. The same chemicals also increased the contraction of these tissue strips in response to the hormone oxytocin.

The findings were published in the latest issue of the Journal of Clinical Investigation.

In an accompanying commentary, researchers from Newcastle University in the United Kingdom said the finding might be viewed as contentious, because prostacyclin is a smooth muscle relaxant. They explained the paradoxical observation by saying that one of the major signaling molecules produced by the uterus just prior to labor is prostacyclin.

More information

The March of Dimes has more about preterm labor.



-- Kevin McKeever



SOURCE: The Journal of Clinical Investigation, news release, Nov. 20, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. The Honorable Edward M. Kennedy, Scientists Mina J. Bissell and Susan Band Horwitz, and Philanthropist Jon M. Huntsman to Receive American Cancer Society Highest Honor for Outstanding Contributions to Cancer Fight
2. Scientists honored for contributions to cancer fight
3. United BioSource Scientists, FDA, and Other Industry Leaders Present to Risk Management and Drug Safety Summit
4. Scientists exploring new compounds to target muscular dystrophy
5. Portuguese scientists discover new mechanism that regulates formation of blood vessels
6. UCLA scientists find cell pathway driving a deadly sub-type of breast cancer
7. Leading Scientists From Around the World Headed to Kansas for Symposium on Combating Deadly Infectious Diseases
8. Cardiff scientists study acute infection in end-stage kidney disease patients
9. Scientists Unravel Mystery of Tamoxifen Resistance
10. Freezing Ovaries Preserves Fertility, Scientists Report
11. TSODs Frank Whyte Provides Negotiation Skills Training to NIH Scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... Heights, NY (PRWEB) , ... December 09, 2016 , ... ... Alcoholism and Drug Dependence, Inc. (NCADD) is recommending the film Whispering Spirits ... states and the District of Columbia as an education tool in the war against ...
(Date:12/9/2016)... ... 09, 2016 , ... An inventor from Cana, Va., wanted to fulfill the ... amusement park rides. , The patent-pending SAFETY STRAP FOR AMPUTEES improves accessibility. It eliminates ... be set up in a matter of minutes, or even seconds. The SAFETY STRAP ...
(Date:12/9/2016)... , ... December 09, 2016 , ... ... at The Pierre Hotel in New York, NY, on December 3rd, to benefit ... and physicians attended the annual event, which raised over $1 million - the ...
(Date:12/9/2016)... ... ... "I had a terrible time trying to get my grandson to use ... nebulizer had a more child-friendly design, then children would be more likely to look ... to avoid the need to deliver medication via a nebulizer mask. The design will ...
(Date:12/8/2016)... Charleston, WV (PRWEB) , ... December 08, 2016 ... ... that it will become Quality Insights beginning January 1, 2017. The name ... emphasizes its commitment to measuring and improving health care quality. , “We are ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... DUBLIN , Dec 9, 2016 ... "High-Throughput Screening Market - Forecast to 2021" report to ... ... adoption of open innovative models in the pharmaceutical and biotechnology ... spending and rising government funding. Emerging markets and growing research ...
(Date:12/9/2016)... , Dec 9, 2016 Research and Markets ... 2016-2020" report to their offering. ... The global travel vaccines market to grow ... The report covers the present scenario and the growth prospects of ... size, the report considers the revenue generated from the sales of ...
(Date:12/8/2016)... LONDON , Dec. 8, 2016 Australia ... GlobalData,s new report, "Australia Ophthalmic Lasers Market Outlook to ... Lasers market. The report provides value, in millions of ... within market segements - Excimer Lasers, Femtosecond Lasers and ... and distribution shares data for each of these market ...
Breaking Medicine Technology: