Navigation Links
Scientists ID Uterine Muscle Switch for Contractions
Date:11/21/2008

Finding may lead to new therapies for preterm labor

FRIDAY, Nov. 21 (HealthDay News) -- Researchers say they've found the switch that activates the uterine muscles for contraction during childbirth, a finding that may lead to therapies for preterm labor.

The molecule prostacyclin normally binds the protein IP on the surface of these uterine muscle cells, keeping them relatively inactive during pregnancy.

But researchers from Dartmouth Medical School in New Hampshire, testing uterine tissue strips from pregnant women undergoing Caesarean birth, found that agonist chemicals can stimulate IP, which then activated proteins involved in muscle contraction. The same chemicals also increased the contraction of these tissue strips in response to the hormone oxytocin.

The findings were published in the latest issue of the Journal of Clinical Investigation.

In an accompanying commentary, researchers from Newcastle University in the United Kingdom said the finding might be viewed as contentious, because prostacyclin is a smooth muscle relaxant. They explained the paradoxical observation by saying that one of the major signaling molecules produced by the uterus just prior to labor is prostacyclin.

More information

The March of Dimes has more about preterm labor.



-- Kevin McKeever



SOURCE: The Journal of Clinical Investigation, news release, Nov. 20, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. The Honorable Edward M. Kennedy, Scientists Mina J. Bissell and Susan Band Horwitz, and Philanthropist Jon M. Huntsman to Receive American Cancer Society Highest Honor for Outstanding Contributions to Cancer Fight
2. Scientists honored for contributions to cancer fight
3. United BioSource Scientists, FDA, and Other Industry Leaders Present to Risk Management and Drug Safety Summit
4. Scientists exploring new compounds to target muscular dystrophy
5. Portuguese scientists discover new mechanism that regulates formation of blood vessels
6. UCLA scientists find cell pathway driving a deadly sub-type of breast cancer
7. Leading Scientists From Around the World Headed to Kansas for Symposium on Combating Deadly Infectious Diseases
8. Cardiff scientists study acute infection in end-stage kidney disease patients
9. Scientists Unravel Mystery of Tamoxifen Resistance
10. Freezing Ovaries Preserves Fertility, Scientists Report
11. TSODs Frank Whyte Provides Negotiation Skills Training to NIH Scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/20/2014)... 20, 2014 An improving macroeconomic landscape ... benefited the Massage Services industry over the ... industry products, the anticipated 1.0% annualized increase in per ... consumers with the means to afford additional massages. “While ... massage in a given year has declined from 2009 ...
(Date:12/20/2014)... Recently, VogueQueen.com, a leading wedding dress wholesaler and ... for 2015. Great discounts are now offered on ... can get a discount, up to 80% off, when ... January 30, 2015. , VogueQueen.com has recently released its ... dress promotion. Many customers worldwide like VogueQueen’s special designs ...
(Date:12/20/2014)... The aftermath of the November 24th hack on Sony ... Hollywood, but worldwide. As reported in the Los ... attack are starting a finger-pointing game which could put some ... are not the only ones affected, regular employees who had ... times ahead, agents and lawyers could be in for some ...
(Date:12/20/2014)... December 20, 2014 Parker & Sons, ... with years of experience in contractor services announces reaching ... services for the homeowners of Arizona. Parker and Sons ... professional contractor technicians that make customer service the number ... Phoenix Arizona and started with one service vehicle and ...
(Date:12/19/2014)... December 19, 2014 Sub Zero Ice Cream ... a blood drive Sunday the 28th from 2pm-6pm at the ... Sawyer Road in Sarasota, FL. , Inquiries regarding time slots ... for participating in the donating process, Sub Zero Ice Cream ... frozen, custom ice cream. , About Sub Zero Ice Cream ...
Breaking Medicine News(10 mins):Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:VogueQueen Big Sale Online For The Coming 2015 2Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 2Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 3Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 4Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 5Health News:Parker & Sons Announces Reaching A Milestone By Providing 40 Years Of Dedicated Contractor Services For Homeowners Of Arizona 2Health News:Parker & Sons Announces Reaching A Milestone By Providing 40 Years Of Dedicated Contractor Services For Homeowners Of Arizona 3Health News:Shark Tank’s Sub Zero Ice Cream Sponsors Blood Drive 2
... VANCOUVER, Dec. 8 /PRNewswire-FirstCall/ - StonePoint Global Brands ... Sterling and Oxford, has launched its upgraded in-room ... contains innovative packaging options, upgraded food selections, Room ... products and numerous other product and service improvements. ...
... 8 Human Genome Sciences, Inc. (Nasdaq: HGSI ) ... results of ACHIEVE 2/3, its Phase 3 trial of Albuferon(R) (albinterferon alfa-2b) ... http://www.newscom.com/cgi-bin/prnh/20080416/HGSLOGO ) , , The ... on Monday, December 8, 2008 at 8:15 am Eastern Time. , ...
... In a region saturated with,sunshine, South Florida physicians ... recent ADT Championship LPGA Playoffs in West Palm ... education presented by the,Women,s Dermatologic Society (WDS). Local ... caddies and members of the media,with 36% of ...
... 8 R&J Public Relations, a leading brand-building public ... in public relations initiatives to promote MAQUET Inc.,s VARIOP ... a leading global provider of medical equipment and systems ... , MAQUET has been ...
... NFL Legends, to announce initiative to support retired players in crisis on ... , ... Minnesota, MN (PRWEB) December 8, 2008 -- A group of current ... an active NFL veteran of the Minnesota Vikings where current players will ...
... joined the staff at the St. John-Clark Pain Treatment ... John, Randall Clark, Tracy Alan Jones, Brunella Lucchi and ... of the clinic,s dream team. From chicago, Wade ... top therapists from across the country who specialize in ...
Cached Medicine News:Health News:StonePoint Announces Completion of Test Market and Launch of New Program 2Health News:Human Genome Sciences to Sponsor Conference Call 2Health News:South Florida Dermatologists Win Over Golf Fans With Sun Safety Outreach at LPGA Playoffs 2Health News:South Florida Dermatologists Win Over Golf Fans With Sun Safety Outreach at LPGA Playoffs 3Health News:R&J Public Relations Selected to Promote MAQUET Inc.'s VARIOP Operating Room Suite in North America 2Health News:NFL Active Players and Mike Ditka to Hold Press Conference 2Health News:NFL Active Players and Mike Ditka to Hold Press Conference 3Health News:The St. John-Clark Pain Treatment Center Forms Manual Therapy 'Dream Team' 2
(Date:12/19/2014)... ALTOS, Calif. , Dec. 18, 2014 /PRNewswire/ ... a new generation of equipment for the testing ... the release of the new Luminary™ Profiler, the ... accurate light-based measurement in a cost-effective, portable unit. ... meet the specific needs of the cannabis industry, ...
(Date:12/19/2014)... DIEGO , Dec. 18, 2014  RESMED INC. (NYSE: ... its second quarter of fiscal year 2015 results on Thursday, ... close. A press release with ResMed,s results will be issued ... host a webcast to discuss operating results and future outlook. ... 1:30 p.m. US Pacific Time and the live webcast of ...
(Date:12/19/2014)... KANSAS CITY, Kan. , Dec. 18, 2014 ... PETX ), a biopharmaceutical company focused on ... for companion animals, today announced positive results from ... company,s innovative drug for treating pain in dogs ... demonstrated improvements in pain assessment scores that were ...
Breaking Medicine Technology:Sage Analytics Develops Breakthrough System for Potency Testing of Cannabis Products 2ResMed To Announce Second Quarter 2015 Results 2Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 2Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 3Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 4Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 5
... Fla., Dec. 2 Jupiter Medical Center ... into its imaging program, the new Signa HDx 1.5T MRI ... of the human body with increased speed, better resolution and ... for patients with renal dysfunction. This results in shorter ...
... , , NEW YORK, Dec. 2 ... five veteran attorneys, led by Neil H. Ekblom, LeClairRyan,s ... in the New York market. Mr. Ekblom, a former ... claims. , The New York team adds to an ...
Cached Medicine Technology:Jupiter Medical Center Announces New High-Definition MRI System 2Neil H. Ekblom and Medical Malpractice Defense Team Join LeClairRyan 2Neil H. Ekblom and Medical Malpractice Defense Team Join LeClairRyan 3
... segment surgeries Vitrectomy-Lensectomy + Irrigation/Aspiration system ... Linear Aspiration. Interchangeable disposable blades can ... Easy to read LED display for ... 1- 600 cuts per minute. Independent ...
Mendez Multi-Purpose LASIK Forceps. To enter, dissect, elevate and smooth the flap. Combined features of Spatula, Dissector and Forceps, Titanium...
Hockey Knife For PRK - Also available in Titanium...
The CGAL gonioscopic contact glass was designed by Roussel and Fankhauser for,laser treatments of the chamber angle. It reduces the laser spot by a factor of 1.5 as compared to a Goldmann Glass....
Medicine Products: