Navigation Links
Scientists ID Protein Aiding Breast Cancer Spread
Date:12/8/2008

Called Menainv, research suggests it's a promising candidate as marker for metastasis

MONDAY, Dec. 8 (HealthDay News) -- A protein that may contribute to the spread of breast cancer has been identified by U.S. researchers.

The protein (called Menainv) is present in invasive cells within a breast tumor. The protein may prove useful as a biomarker for metastatic breast cancer, the scientists said.

These invasive cells move into surrounding tissue and eventually to blood vessels, which provide the cancer cells with a means of moving to other areas of the body. Menainv is not present in noninvasive cancer cells that stay put in a breast tumor.

This is the first study to identify a protein that contributes to the invasive and metastatic ability of tumor cells, rather than "bystander" proteins that show up when cancer cells are invading other tissues, according to the researchers from the Albert Einstein College of Medicine and the Massachusetts Institute of Technology.

"We have micro-needles filled with growth factors and tissue that we insert into a tumor on an anesthetized mouse. If a cell is invasive, within four hours, it will crawl into the needles. We found that mouse breast tumor cells that we engineered to contain Menainv were invasive, whereas cells that did not have Menainv were not," study primary co-author Evanthia T. Roussos, an M.D.-Ph.D. student, said in an Albert Einstein news release.

The researchers also found that tumor cells with Menainv are less likely to be responsive to newer breast cancer treatments that inhibit receptors for epidermal growth factor (EGF), which has been shown to increase a breast cancer cell's invasive potential.

Drugs that inhibit EGF may not be effective against cancer cells that express Menainv, the researchers said. That's because tumor cells with Menainv are so sensitive to EGF that even a small amount of EGF signal not blocked by the drugs may
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
2. Scientists Probe Sepsis Deadly Secrets
3. Scientists puzzled by severe allergic reaction to cancer drug in the middle Southern US
4. Scientists Develop Natural Protection for Stored Foods
5. Scientists detect presence of marburg virus in african fruit bats
6. Scientists Spot Brains Free Will Center
7. Scientists ID Likely Culprit in Popcorn Lung
8. Scientists explain how insulin secreting cells maintain their glucose sensitivity
9. Scripps Research scientists shed new light on how antibodies fight HIV
10. Scientists, physicians present latest findings in personalized cancer treatment and prevention
11. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists ID Protein Aiding Breast Cancer Spread
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... opened by the Beth Israel Medical Center in Manhattan in ... be avoided // , are taking place in New York ... The diabetes centers in the city conduct boot camps aimed ... this the Type 2 diabetes cases have increased by 100%, ...
... of people suffering from stress and other related symptoms. Professor ... levels // of 28 participants. ,They were all ... levels are the best indicators of one’s stress level. ... spent their lunch hour viewing art. It was very surprising ...
... case of Listeria was detected in Australia. An elderly woman died ... suffering from advance stage of cancer // . She was tested ... of confusion among the health care officials in Australia. This woman ... for cancer treatment. But the hospital authorities say that the cause ...
... the age of information and health and combining the two ... for the Ministry of Health (MOH) China has announced that ... AID/HIV epidemic soon. ,In his clarification and statement, "Last year, ... World Health Organization (WHO) jointly estimated China's AIDS epidemic, and ...
... Implants are the perfect replacement of missing teeth in that ... them from their mouth// every time they have a meal ... norm rather than the exception in the fast-paced world of ... November/December issue of General Dentistry, the Academy of General Dentistry’s ...
... Arizona State University have successfully produced Plague vaccines from ... from bioengineered // plant which is found to be ... plague bacterium. The researchers are to start a clinical ... the efficacy of the new vaccine. The researchers have ...
Cached Medicine News:Health News:US Continues Its War On Diabetes 2Health News:Tobacco plant based Vaccine against Plague 2
(Date:12/15/2014)... , December 15, 2014 Heptares ... company, is pleased to announce the grant of multiple ... relating to its GPCR-focused drug discovery platform. The ... the global patent estate covering Heptares, technologies and products ... of patents recently granted by the US Patent Office ...
(Date:12/13/2014)... , Dec. 12, 2014  Radiologists can ... to images, to their referring physicians, electronic health ... using carefully selected technology.  That ... Data Systems Corporation (ADS) at the recent Radiology ... The transmitting of radiology reports in this manner ...
(Date:12/13/2014)... INDIANAPOLIS , Dec. 12, 2014  Novo Nordisk, a ... (CGRT), today announced a multi-year extension of their partnership, that ... No. 83 Novo Nordisk Chip Ganassi Racing entry, driven by ... Kimball, 29, from Camarillo, California ... in the history of INDYCAR to win a race at ...
Breaking Medicine Technology:Heptares Extends Global Patent Protection for GPCR-Focused Drug Discovery Platform With Grant of Core Patents in the United States 2Advanced Data Systems Presents on Interface-Free EHR Communications at RSNA's 2014 Conference: Streamlining Communication of Reports and Images to Referring Physicians 2Advanced Data Systems Presents on Interface-Free EHR Communications at RSNA's 2014 Conference: Streamlining Communication of Reports and Images to Referring Physicians 3Novo Nordisk and Chip Ganassi Racing Teams Announce Multi-Year Sponsorship Agreement for Verizon IndyCar Series 2Novo Nordisk and Chip Ganassi Racing Teams Announce Multi-Year Sponsorship Agreement for Verizon IndyCar Series 3Novo Nordisk and Chip Ganassi Racing Teams Announce Multi-Year Sponsorship Agreement for Verizon IndyCar Series 4Novo Nordisk and Chip Ganassi Racing Teams Announce Multi-Year Sponsorship Agreement for Verizon IndyCar Series 5Novo Nordisk and Chip Ganassi Racing Teams Announce Multi-Year Sponsorship Agreement for Verizon IndyCar Series 6Novo Nordisk and Chip Ganassi Racing Teams Announce Multi-Year Sponsorship Agreement for Verizon IndyCar Series 7
... 7, 2011 Reportlinker.com announces that a ... its catalogue: Aesthetic Devices ... be Driven by Improving Treatment Outcomes and ... http://www.reportlinker.com/p0409144/Aesthetic-Devices-Market-to-2017---Future-Growth-to-be-Driven-by-Improving-Treatment-Outcomes-and-Increase-in-Consumer-Confidence.html Aesthetic ...
... Grifols, a global healthcare company and biopharmaceutical manufacturer based ... an Expert Advisory Council in Transfusion Medicine drawing on ... across the globe.  The role of the Expert Advisory ... Grifols, own transfusion medicine research and development activities. ...
Cached Medicine Technology:Reportlinker Adds Aesthetic Devices Market to 2017 - Future Growth to be Driven by Improving Treatment Outcomes and Increase in Consumer Confidence 2Reportlinker Adds Aesthetic Devices Market to 2017 - Future Growth to be Driven by Improving Treatment Outcomes and Increase in Consumer Confidence 3Grifols Establishes Expert Advisory Council in Transfusion Medicine 2Grifols Establishes Expert Advisory Council in Transfusion Medicine 3
... Since 1991 Intersurgical ... breathing filters, heat and ... oxygen therapy products, hand-held ... range of accessories and ...
... HME product line has the right product ... adults and from intubated patients to patients ... for both anesthesia and critical care applications., ... maximum protection for patients and staff members. ...
... capture the patient`s exhaled heat and moisture ... Small and compact, they are specially treated ... on the tidal volume requirements, select either ... adult HCH is ideal for patient tidal ...
... (HCH) capture the patient`s exhaled heat and ... gas. Small and compact, they are specially ... Depending on the tidal volume requirements, select ... ,The adult HCH is ideal for patient ...
Medicine Products: