Navigation Links
Scientists ID New Biomarker for Prostate Cancer
Date:3/25/2009

Study finds cleaved galectin-3 may serve as treatment target against disease progression

WEDNESDAY, March 25 (HealthDay News) -- A newly identified marker for prostate cancer progression may also offer a new target for treatment, University of Michigan researchers say.

Previous research has found that decreased levels of the marker galectin-3 are linked with neoplastic progression in prostate cancer. However, increased levels of galectin-3 are believed to be associated with tumorigenicity in a number of other tumor types.

The University of Michigan team believed this difference was due to the fact that galectin-3 was cleaved during prostate cancer progression. Their study found that cleaved galectin-3 is present in a late-stage prostate cancer and that reducing levels of galectin-3 inhibited development of metastatic prostate cancer.

The findings suggest that cleaved galectin-3 may serve as a diagnostic marker and treatment target for prostate cancer progression.

The study shows "that galectin-3 is cleaved during the progression of prostate cancer and might be associated with metastasis, cell growth and tumorigenicity. Expression of intact versus cleaved galectin-3 thus might be used as a marker for prognosis of prostate cancer and a therapeutic target for the treatment of prostate cancer," wrote study author Avraham Raz and colleagues.

The study appears in the April issue of The American Journal of Pathology.

More information

The American Cancer Society has more about prostate cancer.



-- Robert Preidt



SOURCE: The American Journal of Pathology, news release, March 25, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Herpes: Scientists find cellular process that fights virus
2. New book chronicles the journeys of women physicians and scientists to fighting cancer
3. University of Washington scientists one step closer to stopping bone loss during spaceflight
4. New Book Chronicles the Journeys of Women Physicians and Scientists to the Front Lines of Fighting Cancer
5. Biotech company cofounded by BIDMC scientists targets natural killer T-cells
6. Scientists trial device to treat chemotherapy-related nausea
7. Scientists closer to understanding how to control high blood sugar
8. First Treatment for Muscular Dystrophy in Sight: Scientists Harness Exon-Skipping in Large Animal to Successfully Treat Duchenne Muscular Dystrophy
9. First treatment for muscular dystrophy in sight: Scientists successfully harness exon-skipping
10. Scientists find gene that modifies severity of cystic fibrosis lung disease
11. UCI scientists to study brain region linked to autism, schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists ID New Biomarker for Prostate Cancer
(Date:2/12/2016)... Omaha, NE (PRWEB) , ... February 12, 2016 , ... ... list of the five most searched jobs via the website of healthcare staffing leader ... professionals in travel nurse jobs , travel therapy positions and in ...
(Date:2/12/2016)... ... February 12, 2016 , ... The aging population and ... long term care. With that, says Patrick Loughney, president of Longtree & ... in long term care environments. His company, which offers prep courses and workshops ...
(Date:2/12/2016)... ... 12, 2016 , ... Basketball is a game for everyone, not just those ... series, sign language translation is featured in the top right of the screen. Every ... lessons has a sign language translator to teach kids the game and how to ...
(Date:2/12/2016)... ... February 12, 2016 , ... With the exception of restorative dentistry, to date there has been ... the recent approval by the FDA, there is a now a new protocol in stopping ... is very simple and quick to apply. The application is as simple as drying ...
(Date:2/11/2016)... ... ... Fitbody Personal Training offers outdoor training classes which includes an equestrian boot ... healthy. Located in Phoenixville, PA, the classes are structured as fun and friendly. , ... want to lose weight and tone up. This class offers a balance of exercises ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... , Kalifornien, 12. Februar 2016  Sequent ... der Aufnahme von Patienten für eine Studie zur ... Aneurysmen („WEB") speziell für die Behandlung von rupturierten ... , MD, Leiter der Neuroradiologie an der Universitätsklinik ... und Hauptprüfarzt der CLARYS-Studie hat den ersten Patienten ...
(Date:2/12/2016)... INDIANAPOLIS , Feb. 12, 2016  Eli Lilly and ... High Court decided the Alimta® (pemetrexed disodium) vitamin regimen patent ... in the UK, France , ... instructions to dilute the product only with dextrose solution.  ... of 2015, the UK Court of Appeal held that Lilly,s ...
(Date:2/12/2016)... February 12, 2016 ... auf den ungedeckten medizinischen Bedarf bei Lungen- ... seines klinischen Forschungsprogramms bekannt. Das Programm, das ... Verbesserungen ihrer respiratorischen Funktionen und anderer klinischer ... ein Medizintechnikunternehmen, das sich auf den ungedeckten ...
Breaking Medicine Technology: