Navigation Links
Scientists ID More Genes Linked to Heart Disease
Date:9/23/2011

FRIDAY, Sept. 23 (HealthDay News) -- Researchers have identified five new genes that play a role in people's risk for heart attack and coronary artery disease -- the most common cause of premature death and disability in the world, according to a new study.

The international consortium said their discovery could help scientists predict coronary artery disease (CAD) and develop new treatments for the condition.

In conducting the study, published online Sept. 22 in the open-access journal PLoS Genetics, the researchers examined more than 49,000 genetic variants in nearly 15,600 cases of CAD along with slightly fewer than 35,000 controls, which included people of European descent and South Asian origin. The investigators also duplicated their findings in 17,121 more cases of the disease and 40,473 controls.

"This is one of the first genetic studies of CAD to include a significant proportion of subjects of South Asian origin, an ethnic group that has a higher risk of CAD," John Danesh, the study's co-principal investigator, said in a journal news release. "Our study shows that many of the genes that affect risk of CAD do so similarly in European Caucasians as in South Asians."

The study findings add to the list of more than 30 genes already known to affect people's risk for coronary artery disease and heart attack, the authors pointed out.

"The findings provide new insights into and understanding of the causal biological pathways that cause heart disease, and particularly highlight the role of lipids and inflammation," the study's co-principal investigator, Nilesh Samani, British Heart Foundation professor of cardiology at the University of Leicester, U.K., said in the news release.

The study authors pointed out that although the individual effects of the new genetic variants they found are small, the treatments that are developed as a result of the findings could have a much broader effect.

More information

The U.S. National Library of Medicine has more about coronary artery disease.

-- Mary Elizabeth Dallas

SOURCE: PLoS Genetics, news release, Sept. 22, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. UCLA scientists find H1N1 flu virus prevalent in animals in Africa
2. Scientists Reconstruct the Movies in Our Minds
3. Scientists Discover Key Gene Mutation Behind Lou Gehrigs Disease
4. Scientists identify a key molecule that blocks abnormal blood vessel growth in tumors
5. NIH scientists find earliest known evidence of 1918 influenza pandemic
6. A*STAR scientists make headway for cancer treatment and cancer prevention with landmark discovery
7. To treat rare disease, NIH scientists repurpose FDA-approved drug
8. UT MD Anderson scientists discover secret life of chromatin
9. Scientists Use Stem Cells for Blood Self-Transfusion
10. Scripps Research scientists reveal how white blood cell promotes growth and spread of cancer
11. Thank Neanderthals for That Healthy Immune System, Scientists Say
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists ID More Genes Linked to Heart Disease
(Date:6/25/2016)... , ... June 25, 2016 , ... "With 30 hand-drawn ... specific project," said Christina Austin - CEO of Pixel Film Studios. , ProHand ... all within Final Cut Pro X . Simply select a ProHand generator and ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of ... recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at Work ... Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World ... with chronic pain and the benefits of holistic treatments, Serenity Recovery Center ... with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the ...
(Date:6/24/2016)... ... 24, 2016 , ... Dr. Amanda Cheng, an orthodontist ... has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be used ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... today at the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra ... authored journal articles published in Emergency Medicine Practice and Pediatric Emergency ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016  Consumers have taken a ... have placed more emphasis on patient outcomes. ... programs in the pharmaceutical industry have evolved beyond ... pharmaceutical companies are focusing on becoming more patient-oriented ... products and services that improve health. ...
(Date:6/24/2016)... , June 24, 2016 ... Markets has announced the addition of the " ... offering. This ... and provides an updated review, including its applications in ... the total market, which includes three main industries: pharmaceutical ...
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June 24, ... -based mobile pulmonary function testing company, is now able to perform ... developed by ndd Medical Technologies , Inc. ... in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ARL ... can get any needed testing done in the comfort of her ...
Breaking Medicine Technology: