Navigation Links
Scientists ID Gene That Predicts Chances of Cold Sores
Date:12/2/2011

FRIDAY, Dec. 2 (HealthDay News) -- Scientists have identified the first gene associated with frequent herpes-related cold sores.

The herpes simplex virus type 1 (HSV-1) affects more than 70 percent of the U.S. population. Once the virus infects the body it is never removed by the immune system. It's transported to nerve cell bodies, where it remains dormant until reactivated.

A cold sore on or around the mouth is the most common visible symptom of HSV-1 reactivation.

"Researchers believe that three factors contribute to HSV-1 reactivation -- the virus itself, exposure to environmental factors and genetic susceptibility," study first author Dr. John Kriesel, a research associate professor of infectious diseases at the University of Utah School of Medicine, said in a university news release. "The goal of our investigation was to define genes linked to cold sore frequency."

He and his team conducted genetic analyses of 355 people infected with HSV-1 and 263 uninfected people and discovered that a gene called C21orf91 was associated with susceptibility to frequent cold sore outbreaks.

Two variants of the gene seemed to protect against HSV-1 reactivation while two other variants seemed to increase the risk of frequent cold sore outbreaks, according to the report published in the Dec. 1 issue of the Journal of Infectious Diseases.

"There is no cure for HSV-1 and, at this time, there is no way for us to predict or prevent cold sore outbreaks," Kriesel said in the news release. "The C21orf91 gene seems to play a role in cold sore susceptibility, and if this data is confirmed among a larger, unrelated population, this discovery could have important implications for the development of drugs that affect cold sore frequency."

More information

The American Academy of Dermatology has more about cold sores and other mouth and lip conditions.

-- Robert Preidt

SOURCE: University of Utah Health Sciences, news release, Nov. 29, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Scientists discover anti-inflammatory polyphenols in apple peels
2. Scientists identify key area that could sever communication between brain and heart in disease
3. Scientists identify defect in brain cell channel that may cause autism-like syndrome
4. Scientists Reveal Monarch Butterfly Genome
5. Scripps Research scientists identify new class of antimalarial compounds
6. NIH-funded scientists identify potential malaria drug candidates
7. Scientists discover how to design drugs that could target particular nerve cells
8. Kessler Foundation scientists awarded grants to study cognition in MS
9. Opening the data bank -- scientists try to match new protein structures
10. Hospital for special surgery physician-scientists share advances in rheumatology research
11. Scientists identify genes that may signal long life in naked mole-rats
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists ID Gene That Predicts Chances of Cold Sores
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for ... for action towards gender equality at their inaugural Summit in New York City in ... reached a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... , ... “The Journey: From the Mountains to the Mission Field”: the story ... the Philippines. “The Journey: From the Mountains to the Mission Field” is the creation ... has taught all ages and currently teaches a class of ladies at her church, ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... to meet the demand of today’s consumer and regulatory authorities worldwide. From Children’s ... experts and tested to meet the highest standard. , These products are ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... Restoration, has recently contributed a medical article to the newly revamped Cosmetic ... Mohebi’s article spotlights the hair transplant procedure known as Follicular Unit Extraction ...
(Date:10/12/2017)... ... , ... Health Literacy Innovations (HLI), creator of the Health ... Cancer Patient Education Network (CPEN), an independent professional organization that shares best practices ... , As CPEN’s strategic partner, HLI will help support CPEN members by ...
Breaking Medicine News(10 mins):
(Date:9/13/2017)...   OrthoAtlanta has been named the official orthopedic ... (AFHC) for the 2018 College Football Playoff (CFP) National Championship ... Stadium in Atlanta, Georgia . OrthoAtlanta is ... campaign, participating in many activities leading up to, and including ... ...
(Date:9/12/2017)... 12, 2017  Consumer reviews on the independent review site ... number one company for hearing aids, ranking it higher than ... ... by Consumers For Hearing Aids ... is an online store that provides high performance, state-of-the-art, German-engineered hearing ...
(Date:9/9/2017)... ... ... – Monday, September 18 th .The Brain Tumor Foundation (BTF) begins a ... public.Where:  BTF,s Mobile MRI Unit – a 70 ... D.C.What:BTF brings its nationwide initiative, the Road to Early Detection Sponsor-A-City Campaign ...
Breaking Medicine Technology: