Navigation Links
Scientists ID Gene That Predicts Chances of Cold Sores
Date:12/2/2011

FRIDAY, Dec. 2 (HealthDay News) -- Scientists have identified the first gene associated with frequent herpes-related cold sores.

The herpes simplex virus type 1 (HSV-1) affects more than 70 percent of the U.S. population. Once the virus infects the body it is never removed by the immune system. It's transported to nerve cell bodies, where it remains dormant until reactivated.

A cold sore on or around the mouth is the most common visible symptom of HSV-1 reactivation.

"Researchers believe that three factors contribute to HSV-1 reactivation -- the virus itself, exposure to environmental factors and genetic susceptibility," study first author Dr. John Kriesel, a research associate professor of infectious diseases at the University of Utah School of Medicine, said in a university news release. "The goal of our investigation was to define genes linked to cold sore frequency."

He and his team conducted genetic analyses of 355 people infected with HSV-1 and 263 uninfected people and discovered that a gene called C21orf91 was associated with susceptibility to frequent cold sore outbreaks.

Two variants of the gene seemed to protect against HSV-1 reactivation while two other variants seemed to increase the risk of frequent cold sore outbreaks, according to the report published in the Dec. 1 issue of the Journal of Infectious Diseases.

"There is no cure for HSV-1 and, at this time, there is no way for us to predict or prevent cold sore outbreaks," Kriesel said in the news release. "The C21orf91 gene seems to play a role in cold sore susceptibility, and if this data is confirmed among a larger, unrelated population, this discovery could have important implications for the development of drugs that affect cold sore frequency."

More information

The American Academy of Dermatology has more about cold sores and other mouth and lip conditions.

-- Robert Preidt

SOURCE: University of Utah Health Sciences, news release, Nov. 29, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Scientists discover anti-inflammatory polyphenols in apple peels
2. Scientists identify key area that could sever communication between brain and heart in disease
3. Scientists identify defect in brain cell channel that may cause autism-like syndrome
4. Scientists Reveal Monarch Butterfly Genome
5. Scripps Research scientists identify new class of antimalarial compounds
6. NIH-funded scientists identify potential malaria drug candidates
7. Scientists discover how to design drugs that could target particular nerve cells
8. Kessler Foundation scientists awarded grants to study cognition in MS
9. Opening the data bank -- scientists try to match new protein structures
10. Hospital for special surgery physician-scientists share advances in rheumatology research
11. Scientists identify genes that may signal long life in naked mole-rats
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists ID Gene That Predicts Chances of Cold Sores
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... ... ... in a crisis. Her son James, eight, was out of control. Prone to extreme mood ... something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a ... children and say he was going to kill them. If we were driving on ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Global law firm ... 2016 Legal Elite. The attorneys chosen by their peers for this recognition are considered ... Seven Greenberg Traurig Shareholders received special honors as members of this year’s Legal Elite ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Comfort Keepers® ... American Cancer Society and the Road To Recovery® program to drive cancer patients to ... and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016   Bay ... Rehabilitation Network,s Dean Center for Tick Borne ... Medicine and Rehabilitation, MIT Hacking Medicine, University of ... Innovation, today announced the five finalists of ... Lyme disease.  More than 100 scientists, clinicians, researchers, ...
(Date:6/24/2016)... June 24, 2016 Research ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural Health ... Structural electronics involves electronic and/or electrical ... structures, replacing dumb structures such as vehicle bodies ...
(Date:6/24/2016)... , June 24, 2016 Dehaier Medical ... the "Company"), which develops, markets and sells medical devices ... , signed a strategic cooperation agreement with Hongyuan ... "Hongyuan Supply Chain") on June 20, 2016, to develop ... the strategic cooperation agreement, Dehaier will leverage Hongyuan Supply ...
Breaking Medicine Technology: