Navigation Links
Scientists ID Cancer-Causing Agent in Smokeless Tobacco
Date:8/22/2012

WEDNESDAY, Aug. 22 (HealthDay News) -- Scientists have linked a specific ingredient in smokeless tobacco products to an increased risk for oral cancer, in research using rodents.

The culprit, found in such products as chewing tobacco and snuff, is a nitrosamine compound called (S)-NNN. Nitrosamines in tobacco are considered to be cancer-causing, according to the U.S. National Cancer Institute.

Authors of the new study acknowledge that such compounds are found in many foods, including beer and bacon. But they say that levels are much higher in smokeless tobacco products, leading them to suggest that the U.S. government should therefore ban or regulate (S)-NNN.

The researchers are scheduled to present their findings Wednesday at the American Chemical Society annual meeting, in Philadelphia.

"This is the first example of a strong oral-cavity carcinogen that's in smokeless tobacco," study author Stephen Hecht, from the University of Minnesota, said in a society news release. "Our results are very important in regard to the growing use of smokeless tobacco in the world, especially among younger people who think it is a safer form of tobacco than cigarettes. We now have the identity of the only known strong oral carcinogen in these products."

Roughly 9 million Americans use smokeless tobacco products, according to the release. This has raised alarm about the potentially elevated risk users may face for the mouth, esophageal and pancreatic cancer.

In the study, laboratory rats were given two types of low-dose NNN for 17 months. That timeframe was equated to human consuming a half-tin of smokeless tobacco on a daily basis for 30 years.

One type of NNN known as (S)-NNN was found to prompt the onset of oral and esophageal tumors.

In theory, (S)-NNN can be removed from smokeless tobacco products, with some particular products already featuring reduced levels of the compound, according to the release.

"The most popular brands of smokeless tobacco that are sold in the U.S. have unacceptably high levels of this particular carcinogen," Hecht said. "And smokeless tobacco is a known cause of oral cancer. Obviously, we need to decrease the levels of this material in all smokeless tobacco products or eliminate it altogether."

Scientists note that research with animals often fails to provide similar results in humans. Because this study was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

For more on smokeless tobacco, visit the U.S. National Institutes of Health.

--Alan Mozes

SOURCE: American Chemical Society, news release, Aug. 22, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. UCSB scientists examine effects of manufactured nanoparticles on soybean crops
2. Scientists report promising new direction for cognitive rehabilitation in the elderly
3. Scientists to investigate preventing life-threatening complications in transplant patients
4. Scientists decode TREX which could see new treatments for cancer realized
5. Scientists devise new strategy to destroy multiple myeloma
6. Scientists ID New Gene Regions Linked to Type 2 Diabetes
7. Scientists discover how iron levels and a faulty gene cause bowel cancer
8. Scripps Florida scientists awarded nearly $1.5 million to develop new approaches to treat cancer
9. Scientists ID New Gene Linked to Vision Loss in Infants
10. Fruit flies light the way for A*STAR scientists to pinpoint genetic changes that spell cancer
11. NIH scientists identify likely predictors of hepatitis C severity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists ID Cancer-Causing Agent in Smokeless Tobacco
(Date:6/25/2016)... ... 2016 , ... Austin residents seeking Mohs surgery services, can now turn to ... Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to ... fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand ... project," said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s ... within Final Cut Pro X . Simply select a ProHand generator and drag ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. ... his M.D from the David Geffen School of Medicine at UCLA. He trained in ... to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he ...
(Date:6/25/2016)... ... 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland ... iHire in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness ... & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of ...
(Date:6/24/2016)... ... 24, 2016 , ... A recent article published June 14 on ... article goes on to state that individuals are now more comfortable seeking to undergo ... such as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 2016 Jazz Pharmaceuticals plc (Nasdaq: ... Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended ("HSR"), ... Inc. ("Celator"; Nasdaq: CPXX ) expired effective ... As previously announced on May 31, 2016, ... agreement under which Jazz Pharmaceuticals has commenced a tender ...
(Date:6/26/2016)... 26, 2016 Story Highlights: ... models within the health care industry is causing providers ... , Deloitte offers a suite of solutions for ... impacting efficient cost optimization: labor resource analysis, revenue cycle ... facilitate better outcomes and better economics ...
(Date:6/24/2016)... 2016  Collagen Matrix, Inc., ("Collagen Matrix") the ... of collagen and mineral based medical devices for ... Bill Messer has joined the company as ... the growing portfolio of oral surgery, neurosurgery, orthopaedic ... joins the Collagen Matrix executive team as an ...
Breaking Medicine Technology: