Navigation Links
Scientists ID Cancer-Causing Agent in Smokeless Tobacco
Date:8/22/2012

WEDNESDAY, Aug. 22 (HealthDay News) -- Scientists have linked a specific ingredient in smokeless tobacco products to an increased risk for oral cancer, in research using rodents.

The culprit, found in such products as chewing tobacco and snuff, is a nitrosamine compound called (S)-NNN. Nitrosamines in tobacco are considered to be cancer-causing, according to the U.S. National Cancer Institute.

Authors of the new study acknowledge that such compounds are found in many foods, including beer and bacon. But they say that levels are much higher in smokeless tobacco products, leading them to suggest that the U.S. government should therefore ban or regulate (S)-NNN.

The researchers are scheduled to present their findings Wednesday at the American Chemical Society annual meeting, in Philadelphia.

"This is the first example of a strong oral-cavity carcinogen that's in smokeless tobacco," study author Stephen Hecht, from the University of Minnesota, said in a society news release. "Our results are very important in regard to the growing use of smokeless tobacco in the world, especially among younger people who think it is a safer form of tobacco than cigarettes. We now have the identity of the only known strong oral carcinogen in these products."

Roughly 9 million Americans use smokeless tobacco products, according to the release. This has raised alarm about the potentially elevated risk users may face for the mouth, esophageal and pancreatic cancer.

In the study, laboratory rats were given two types of low-dose NNN for 17 months. That timeframe was equated to human consuming a half-tin of smokeless tobacco on a daily basis for 30 years.

One type of NNN known as (S)-NNN was found to prompt the onset of oral and esophageal tumors.

In theory, (S)-NNN can be removed from smokeless tobacco products, with some particular products already featuring reduced levels of the compound, according to the release.

"The most popular brands of smokeless tobacco that are sold in the U.S. have unacceptably high levels of this particular carcinogen," Hecht said. "And smokeless tobacco is a known cause of oral cancer. Obviously, we need to decrease the levels of this material in all smokeless tobacco products or eliminate it altogether."

Scientists note that research with animals often fails to provide similar results in humans. Because this study was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

For more on smokeless tobacco, visit the U.S. National Institutes of Health.

--Alan Mozes

SOURCE: American Chemical Society, news release, Aug. 22, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. UCSB scientists examine effects of manufactured nanoparticles on soybean crops
2. Scientists report promising new direction for cognitive rehabilitation in the elderly
3. Scientists to investigate preventing life-threatening complications in transplant patients
4. Scientists decode TREX which could see new treatments for cancer realized
5. Scientists devise new strategy to destroy multiple myeloma
6. Scientists ID New Gene Regions Linked to Type 2 Diabetes
7. Scientists discover how iron levels and a faulty gene cause bowel cancer
8. Scripps Florida scientists awarded nearly $1.5 million to develop new approaches to treat cancer
9. Scientists ID New Gene Linked to Vision Loss in Infants
10. Fruit flies light the way for A*STAR scientists to pinpoint genetic changes that spell cancer
11. NIH scientists identify likely predictors of hepatitis C severity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists ID Cancer-Causing Agent in Smokeless Tobacco
(Date:6/22/2017)... ... ... Despite its pervasiveness, many physicians are unfamiliar with how best to treat ... practice. Now, however, a timely review has been published in the Journal of ... NeuP and educating preclinical scientists on its diagnosis and choice of treatment. , The ...
(Date:6/20/2017)... Murfreesboro, Tennessee (PRWEB) , ... June 20, 2017 ... ... chronic care services, announced today that Claritas Capital, a Nashville-based private equity firm, ... to accelerate our expansion plans for some time, and Claritas Capital offers the ...
(Date:6/20/2017)... ... June 20, 2017 , ... Hayes, Inc., ... a new eBook titled “ 5 Questions to Ask Before Entering the Maze ... the Genetic Test Evaluation (GTE) team, the book explores the various types of ...
(Date:6/20/2017)... ... 20, 2017 , ... AMC Health , the leading provider of proven ... trials market. Similar to its approach in demonstrating positive outcomes in the healthcare market, ... proving the value of eVisits to support virtual studies. , In a ...
(Date:6/20/2017)... ... June 20, 2017 , ... With certifications and experience that puts ... NJ, Drs. Adam and Hal Kimowitz are currently accepting new patients at their practice ... can cause for some patients, which is why they offer the latest in modern ...
Breaking Medicine News(10 mins):
(Date:6/1/2017)... 2017 Nutriceutical Holdings (NH), parent company of ... and KD Pharma Group have decided to join forces ... Pharma Group. KD Pharma Group will become the largest ... the entire company. "We believe we have ... to growing the NH companies by providing us with ...
(Date:5/29/2017)... TEL AVIV, Israel, May 29, 2017  Cellect Biotechnology ... of innovative technology which enables the functional selection of ... financial results for the first quarter ended March 31 ... pleased with our accomplishments in the first quarter of ... the first quarter, we announced the treatment of the ...
(Date:5/23/2017)... 23, 2017  Leaf Healthcare, recognized for developing ... for pressure ulcer prevention, will unveil its comprehensive ... Critical Care Nurses, National Teaching Institute and Critical ... The Leaf Patient Monitoring System is the first ... environment.  The system seamlessly tracks patient movement throughout ...
Breaking Medicine Technology: