Navigation Links
Scientists Hot on Trail of New Antibiotics
Date:10/17/2008

Natural compounds could mean faster treatments for TB, fight other drug-resistant bacteria

FRIDAY, Oct. 17 (HealthDay News) -- Researchers believe they are close to perfecting a new class of broad-spectrum antibiotics that could counter increasingly drug-resistant bacteria, a new study says.

The new antibiotics compounds -- all of which are natural products produced by certain bacteria to battle other bacteria -- also show promise as a more effective and faster treatment for tuberculosis. One in three people worldwide carries TB, and today's antibiotics are not efficient in combating it.

The new research, published in the Oct. 17 issue of the journal Cell, is encouraging, because bacterial infectious diseases are responsible for a quarter of all deaths worldwide. For all major bacterial pathogens, strains resistant to at least one current antibiotic have arisen, according to one researcher.

"For six decades, antibiotics have been our bulwark against bacterial infectious diseases," Richard Ebright, a Howard Hughes Institute investigator at Rutgers University, said in an interview issued by the journal's publisher. "Now, this bulwark is collapsing. There is an urgent need for new antibiotic compounds and practical new targets."

The new antibiotic compounds under study are myxopyronin, corallopyronin, and ripostatin. They block the action in bacteria of RNA polymerase, an essential protein in all organisms that is necessary to transcribe the genetic instructions in DNA into RNA, which in turn directs the assembly of proteins.

"RNA polymerase has a shape reminiscent of a crab claw, with two prominent pincer-like projections," Ebright said. "Just as with a real crab claw, one pincer stays fixed and one pincer moves, opening and closing to keep DNA in place. The pincer that moves does so by rotating about a hinge. Our studies show that the three antibiotics bind to and jam this hinge." '/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
2. Scientists Probe Sepsis Deadly Secrets
3. Scientists puzzled by severe allergic reaction to cancer drug in the middle Southern US
4. Scientists Develop Natural Protection for Stored Foods
5. Scientists detect presence of marburg virus in african fruit bats
6. Scientists Spot Brains Free Will Center
7. Scientists ID Likely Culprit in Popcorn Lung
8. Scientists explain how insulin secreting cells maintain their glucose sensitivity
9. Scripps Research scientists shed new light on how antibodies fight HIV
10. Scientists, physicians present latest findings in personalized cancer treatment and prevention
11. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Hot on Trail of New Antibiotics
(Date:3/31/2015)... (PRWEB) March 31, 2015 Simeon Boyd, ... a nearly $4 million, five-year grant from the National ... team of physicians and scientists from more than 10 ... including Australia, Brazil, Bulgaria, Germany, Hungary, Italy and the ... the bony plates of the skull in infants. , ...
(Date:3/31/2015)... Indosoft, developer of the Q-Suite call center software suite, ... their 5.x line. The industry leading contact center ACD ... world for more than a decade. By announcing an end ... can fully embrace newer Asterisk features and improve performance. , ... for more than a decade. The use of Asterisk, a ...
(Date:3/31/2015)... On March 26, 2015, Vogue Magazine UK, ... Slope?” provides a look into the trend of young women ... laser treatments . The article suggests that celebrity endorsements (Beyoncé ... as Kim Kardashian and Kylie Jenner are the drivers behind ... as significant influences on the self-esteem of teenagers. (see: goo.gl/NmaB4q) ...
(Date:3/31/2015)... March 31, 2015 Dr. ... by the American Board of Dermatology and fellowship ... research training at the National Cancer Institute of ... his internship in internal medicine at the Emory ... Pennsylvania in Philadelphia. Dr. Li pursued further training ...
(Date:3/31/2015)... (PRWEB) March 31, 2015 At Summit Breast ... all patients in a calm and caring manner. , Summit ... diagnosis and surgical treatment of breast cancer. They treat ... but from all over the world. Their doctors continue ... publications. , The seeds for Summit Breast Care were planted ...
Breaking Medicine News(10 mins):Health News:International team of researchers led by UC Davis receives $4 million NIH grant to study skull disorder in infants 2Health News:International team of researchers led by UC Davis receives $4 million NIH grant to study skull disorder in infants 3Health News:Indosoft Announces End of Life for Asterisk 1.4 Support in Q-Suite 5 Call Center Software 2Health News:Cosmetic Surgery: Does Social Media Pressure Young Girls to Get Botox and Fillers? 2Health News:Dr. Andrew Li of Warren Skin Care Center Is Celebrating 3 Years Recognized as an "NJ Top Doc" 2Health News:Summit Breast Care is Celebrating Four Years as "NJ Top Docs" 2
... in liver, which may trigger disease, study says , , FRIDAY, ... to play a role in insulin resistance that can be ... sweetener found in most sodas and many processed foods. ... protected from insulin resistance when PGC-1b activity was blocked in ...
... The United States has intervened in a whistleblower suit filed ... Inc. (CHS) and three of its hospitals in New Mexico: ... in Deming, and Alta Vista Regional Hospital in Las Vegas. ... violated the False Claims Act (FCA) by knowingly causing to ...
... Concern Audit OpinionISELIN, N.J., March 6 Pharmos Corporation ... has received a Nasdaq Staff Determination that the company ... equity requirement for continued listing. Unless the company appeals ... and registration on The Nasdaq Stock Market. Pharmos does ...
... may affect diaphragm, chest wall to decrease volume, study ... big around the middle can put the squeeze on ... than 120,000 people. , It was already known that ... women and greater than 40 inches for men) was ...
... Donate Life - Texas Registry will be in front of the Capitol Grill ... p.m. educating people on the donor registration process and getting them signed up ... ... Glenda Dawson Donate Life - Texas Registry will be in front ...
... Massachusetts General Hospital (MGH) clinics indicated they would be willing ... have their daughters and even sons vaccinated in order to ... March issue of Gynecologic Oncology also found that ... to accept HPV vaccine as non-Latinos. , "Since ...
Cached Medicine News:Health News:Gene Explains How High-Fructose Diets Lead to Insulin Resistance 2Health News:United States Joins Suit Against Community Health Systems Inc. and Three of Its Hospitals in New Mexico 2Health News:Pharmos Corporation Announces Receipt of Nasdaq Delisting Determination 2Health News:Pharmos Corporation Announces Receipt of Nasdaq Delisting Determination 3Health News:Belly Fat Puts the Pressure on Lungs 2Health News:Donate Life Day at the Capitol to Increase Awareness for Organ Donation and Registration 2Health News:Donate Life Day at the Capitol to Increase Awareness for Organ Donation and Registration 3Health News:Donate Life Day at the Capitol to Increase Awareness for Organ Donation and Registration 4Health News:Both Latino and non-Latino women likely to accept HPV vaccination for selves and children 2Health News:Both Latino and non-Latino women likely to accept HPV vaccination for selves and children 3
(Date:3/31/2015)... 2015 PGI has announced an expansion of ... America at its San Luis ... plant expansion is centered on solving the challenge of ... for personal care product manufacturers. The ... slitting and packaging, will allow customers to take advantage ...
(Date:3/31/2015)... YORK , March 31, 2015 Immune ... announced today that it intends to expand its planned ... human monoclonal antibody targeting eotaxin-1. Bullous Pemphigoid is an ... 60,000 patients in the US and Europe ... to start enrolling patients in a Phase II clinical ...
(Date:3/31/2015)... , March 31, 2015   Unique Pharmaceuticals ... transformation is complete and the company has initiated sterile ... "Our goal as a company is to meet ... Travis Leeah . "Meeting the new regulations is validation ... We,re embracing the future of our industry, investing in ...
Breaking Medicine Technology:PGI Expands Manufacturing Capabilities At Mexico Plant 2Immune Pharmaceuticals To Expand Bullous Pemphigoid Clinical Development Plan For Bertilimumab 2Immune Pharmaceuticals To Expand Bullous Pemphigoid Clinical Development Plan For Bertilimumab 3Immune Pharmaceuticals To Expand Bullous Pemphigoid Clinical Development Plan For Bertilimumab 4Unique Pharmaceuticals Launches Sterile Operations under New Federal Guidance 2Unique Pharmaceuticals Launches Sterile Operations under New Federal Guidance 3
... NEW YORK, June 22, 2011 Reportlinker.com ... is available in its catalogue: ... http://www.reportlinker.com/p0559270/US-Urinary-Incontinence-Devices.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=Food_Ingredient ... the urinary incontinence device market. The urinary ...
... June 22, 2011 /PRNewswire-Asia/ -- Winner Medical Group Inc. (Nasdaq: ... leading manufacturer of medical dressings, medical disposables and non-woven fabric ... the Company,s management team will present at the 2011 Brean ... held on June 27 and 28, 2011 at the JW ...
Cached Medicine Technology:Reportlinker Adds U.S. Urinary Incontinence Devices 2Reportlinker Adds U.S. Urinary Incontinence Devices 3Reportlinker Adds U.S. Urinary Incontinence Devices 4Winner Medical to Present at Brean Murray, Carret & Co. Beijing China Growth Conference 2Winner Medical to Present at Brean Murray, Carret & Co. Beijing China Growth Conference 3
Auto refractometer....
... most advanced automatic refractor/keratometer ... today. It adds the ... readings simultaneously. It also ... focusing, automatic tracking, automatic ...
... Laserex Tango ophthalmic laser system provides two ... laser and a photodisruptor for posterior capsulotomy ... frequency-doubled Nd:YAG producing pulsed 532 nm light. ... 1064 nm. The appropriate laser can be ...
Thin and smooth jaws, designed to enter trough 3 mm incision, cross action....
Medicine Products: