Navigation Links
Scientists Find Way to Heal Broken Bones Faster
Date:4/28/2010

idea that tissues might heal faster if the Wnt signal was ramped up.

The first used a genetic approach, involving mice that had been genetically engineered to respond better to a Wnt signal, then administering purified Wnt via fat particles known as liposomes.

The second strategy involved raising levels of the Wnt protein in normal mice. Both groups of mice had sustained bone injuries.

"Both experiments showed us the same thing, that when Wnt signals were prolonged in an injury site then healing was much more robust," Helms reported. "When we delivered this form of the protein in a little lipid [fat] particle to an injury site, we accelerated the healing quite dramatically."

In fact, within the first three days, those mice had 3.5 times more new bone than the mice in the other groups, according to background information about the study.

Helms and her colleagues believe Wnt causes bone stem cells to divide more and turn into bone-forming cells much sooner.

J. Edward Puzas, a professor of orthopedics and senior associate dean for basic research at the University of Rochester Medical Center, added that the idea might also benefit people who sustain potentially life-threatening fractures as a result of osteoporosis.

In separate ongoing studies, Puzas is finding that the osteoporosis drug Forteo is also useful in healing bones.

The Stanford group is now expanding its work to speed tissue regeneration after skin wounds, heart attacks and stroke.

More information

The American Academy of Orthopaedic Surgeons has more on bone fractures.



SOURCES: Jill Helms, Ph.D., DDS, professor, surgery and plastic and reconstructive surgery, Stanford University School of Medicine, Palo Alto,
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Scientists Report Key Finding in Breast Cancer Research
2. Rutgers Stem Cell Research Center derives new cell lines and trains stem cell scientists
3. CSHL scientists discover how a tumor suppressor induces senescence and staves off cancer
4. Scientists find key to gene that promotes cancer metastasis
5. Scientists find gene linked to schizophrenia
6. Prevalence of HIV in Africa is leading to new strains of Salmonella, say scientists
7. Scientists Grow Replacement Blood Vessels From Stem Cells
8. Southampton scientists begin Phase II patient trial for new asthma treatment
9. Scientists find out why living things are the size they are -- and none other
10. Scientists: Soccer improves health, fitness and social abilities
11. Pan-Asian hub for life scientists to open in Suzhou, China, on Monday, April 6
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... NY (PRWEB) August 30, 2014 ... throughout the planet has been one of the ... order to create a positive impact around the ... and staffed with top trained executives and trainers ... of people worldwide. Vital statistics demonstrate that ...
(Date:8/30/2014)... August 30, 2014 Market Research ... 2009-2019 is a professional and in-depth market survey ... report firstly reviews the basic information of Cell ... The report then explores global and China’s top ... capacity, Production value, and market share etc. The ...
(Date:8/30/2014)... 30, 2014 Insomnia causes disturbances in every ... how they unknowingly developed insomnia and the steps often used ... Tune in to the show at this link: ... live on August 30, and will be podcasted at ... go to DrCarolFrancisTalkRadio.com. , "Insomnia causes countless unrecognized ...
(Date:8/30/2014)... 2014 In today’s world, a good night’s ... Snoring and sleep apnea (a medical problem where the airway ... bed partners of the rest they need to face their ... snores and 20 million people in the United States alone ... and treated; and of those treated, many cannot tolerate their ...
(Date:8/30/2014)... Administration of colchicine, a plant-based medication commonly used ... showed mixed results in reducing potential complications from ... the risk of gastrointestinal adverse effects, according to ... study is being released early online to coincide ... Cardiology Congress. , Common complications after cardiac surgery ...
Breaking Medicine News(10 mins):Health News:Cradle of Aviation Museum Opens Its Doors to Long Island Scientologists 2Health News:Cell Disruptor Industry Global and Chinese Analysis for 2009-2019 in New Research Report at ReportsnReports.com 2Health News:Cell Disruptor Industry Global and Chinese Analysis for 2009-2019 in New Research Report at ReportsnReports.com 3Health News:Cell Disruptor Industry Global and Chinese Analysis for 2009-2019 in New Research Report at ReportsnReports.com 4Health News:Sleepless Nights, Exhausting Days, Mental Fog – Relief for Insomnia With Clinical Psychologist Dr. Carol Francis 2Health News:Snoring: Bad for Relationships, Bad for Health 2Health News:Snoring: Bad for Relationships, Bad for Health 3Health News:Medication shows mixed results in reducing complications from cardiac surgery 2
... deaths every year, even though it has been known for ... reduces the chance of being bitten by the mosquitoes which ... how best to increase the use of such nets, particularly ... in the latest issue of PLoS Medicine, has shown that ...
... (hypertension) is associated with an increased risk of heart ... known as NSAIDs, for example to treat individuals with ... hypertension is not clear because they inhibit the generation ... affect blood pressure and the effects of inhibiting the ...
... Md. Scientists have shown that recently developed mouse ... may not be as effective as previously assumed. Sascha ... lead author Eva Czirr, Ph.D. student at the University ... 24 issue of the Journal of Biological Chemistry ...
... irradiation after chemotherapy significantly reduces the risk of ... lung cancer (SCLC), according to the results of ... published in the New England Journal of Medicine ... an aggressive tumor that constitutes nearly 15% of ...
... has revealed a breakdown in normal patterns of emotional ... depression to suppress negative emotional states. Efforts by depressed ... images enhanced activity in several brain areas, including the ... according to a report in the August 15 issue ...
... team of Mayo Clinic researchers has discovered a new, ... joints, potentially leading to better treatment options and patient ... adhere to the prosthetic surface, was tested in a ... joints who were having their prosthetic joints removed for ...
Cached Medicine News:Health News:Free distribution of insecticide-treated mosquito nets can save lives 2Health News:Effectiveness of mouse breeds that mimic Alzheimer's disease symptoms questioned 2Health News:Effectiveness of mouse breeds that mimic Alzheimer's disease symptoms questioned 3Health News:Prophylactic cranial irradiation in small cell lung cancer significantly increases survival 2Health News:Prophylactic cranial irradiation in small cell lung cancer significantly increases survival 3Health News:Brain imaging reveals breakdown of normal emotional processing 2Health News:Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints 2Health News:Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints 3
(Date:8/29/2014)... Aug. 29, 2014 Research and Markets ... and Development Trend Forecast of Pharmaceutical Equipment Market in ... Research and Development Trend Forecast of Pharmaceutical Equipment ... analyzes China,s pharmaceutical equipment industry ... demand, competition landscape, and business performance of domestic major ...
(Date:8/29/2014)... Diseases largely eradicated in the United States ... declared eliminated in 2000, yet the CDC reports 593 ... incidence in 20 years. In July, California,s ... problem of "epidemic proportions." Across ... preventable diseases—in part because some parents (more than 10 ...
(Date:8/29/2014)... Ohio , Aug. 29, 2014  In ... how to leverage a hospital pharmacy as a strategic ... and national practice leader for Cardinal Health,s Innovation Delivery ... pharmacy care can benefit both hospitals and patients. ... is only one part of their job in a ...
Breaking Medicine Technology:Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2Vaccines at the Crossroads: Outbreaks On the Rise Across America 2Vaccines at the Crossroads: Outbreaks On the Rise Across America 3Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 2Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 3Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 4
... GeneXpert(R) System ... ... today announced the U.S. Food & Drug Administration (FDA) categorized,Cepheid,s ... Clinical Laboratory Improvement Amendments (CLIA).,The new test is designed for ...
... Michael J. Fox,Foundation today announced the availability of ... toward transformative treatments and a cure for,Parkinson,s disease., ... researchers through the,Foundation,s Pipeline Programs, five separate initiatives ... drug development pipeline. This includes,early-stage discovery research, translational ...
Cached Medicine Technology:Cepheid Molecular Diagnostic Test for Positive Blood Culture Bottles Categorized 'Moderate Complexity' by FDA 2Cepheid Molecular Diagnostic Test for Positive Blood Culture Bottles Categorized 'Moderate Complexity' by FDA 3Cepheid Molecular Diagnostic Test for Positive Blood Culture Bottles Categorized 'Moderate Complexity' by FDA 4Michael J. Fox Foundation Announces $11 Million in 2009 Funding for Translational, Pre-Clinical and Clinical Parkinson's Disease Research 2Michael J. Fox Foundation Announces $11 Million in 2009 Funding for Translational, Pre-Clinical and Clinical Parkinson's Disease Research 3Michael J. Fox Foundation Announces $11 Million in 2009 Funding for Translational, Pre-Clinical and Clinical Parkinson's Disease Research 4
Steel Knife with box for the Series 8000 Sliding Microtome. C-Profile, 240 x 33 x13m, 22 Degree angle, tapped to accept holder for Shandon knife sharpener....
... M3500 Radial Microtome has a look that is ... range of functions and capabilities that will please ... years of experience and knowledge but still breaking ... M3500 Microtome will be the answer to many ...
Clock oil, 6 grams net...
Coarse abrasive for knife sharpening, 6 grams net...
Medicine Products: