Navigation Links
Scientists Find Way to Boost 'Good' Cholesterol in Mice
Date:11/16/2010

TUESDAY, Nov. 16 (HealthDay News) -- New animal research has identified a sequence of genetic material that appears to stabilize levels of so-called "good" cholesterol, at least in mice.

Working with mice and primates, the study team found that the sequence in question -- labeled "miR-33a" -- helps to regulate cholesterol by serving as a kind of "off" switch for certain genes.

Specifically, the sequence was found to inhibit production of three proteins, thereby limiting the amount of circulating high-density lipoprotein (HDL) cholesterol found in the body.

In turn, if the sequence is "silenced," HDL levels go up, according to study co-authors Katey Rayner and Kathryn Moore, both of New York University Medical Center in New York City.

Rayner and Moore are slated to present their findings Tuesday in Chicago at the annual meeting of the American Heart Association.

Their observations are part of an effort to develop new treatments designed to elevate HDL levels.

Working with mice suffering from coronary artery disease, the researchers found that inhibiting the identified sequence prompted a 36 percent rise in HDL levels.

What's more, the effort also appeared to achieve some measure of reversal of atherosclerosis in the mice, with a reduction in lesions of 35 percent.

Both findings suggest that the sequence could prove to be an optimal target for the development of future HDL-raising drug therapies.

Experts note that research presented at meetings isn't subjected to the same type of scrutiny that research published in peer-reviewed journals undergoes. And research in animals often doesn't translate into success in human studies.

More information

For more on good cholesterol, visit the American Heart Association.

-- Alan Mozes

SOURCE: American Heart Association, news release, Nov. 16, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. NIH scientists explore 1510 influenza pandemic and lessons learned
2. Scientists at IRB Barcelona and BSC publish the worlds largest video data bank of proteins
3. NIH scientists unveil mechanisms of immune reconstitution inflammatory syndrome
4. Scientists Use Tarantulas to Explore Human Fear
5. Scientists Say Theyve Made Blood From Skin
6. Hospital for Special Surgery scientists share advances in lupus and related conditions
7. Scientists develop method to keep surgically-removed prostate tissue alive and working for week
8. Scientists turn a new leaf to discover a compound in daffodils that targets brain cancer
9. Scientists Report Early Success in Growing Mini Liver in Lab
10. Scientists seek urgent treatment for fatal sleeping sickness
11. Scientists investigate evolution of new polio virus
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Find Way to Boost 'Good' Cholesterol in Mice 
(Date:6/24/2016)... ... , ... A recent article published June 14 on E Online ... on to state that individuals are now more comfortable seeking to undergo not only ... calf and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) ...
(Date:6/24/2016)... Fla. (PRWEB) , ... June 24, 2016 , ... Global ... Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this recognition ... Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this year’s ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine presented ... in Emergency Medicine conference in Ponte Vedra Beach, FL. The awards honor the ... Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , “With this award, ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Venture ... Golf Classic Tournament held on June 20th at the Woodmont Country Club at ... Luke’s Wings, an organization dedicated to helping service members that have been wounded in ...
(Date:6/24/2016)... ... June 24, 2016 , ... Southern Illinois ... are co-chairs for the Illinois State Dental Society (ISDS) Foundation’s Mission of Mercy ... Gateway Convention Center in Collinsville. , They expect to treat approximately ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016  Guerbet announced today that it has ... Horizon Award . One of 12 suppliers ... for its support of Premier members through exceptional local ... and commitment to lower costs. ... of our outstanding customer service from Premier," says ...
(Date:6/23/2016)... -- The Biotechnology industry might still be ... opportunities to investors. Stock-Callers.com assesses the recent performances of ... XON ), Vertex Pharmaceuticals Inc. (NASDAQ: ... ), and Regeneron Pharmaceuticals Inc. (NASDAQ: REGN ... complimentary trade alerts at: http://stock-callers.com/registration ...
(Date:6/23/2016)... Research and Markets has announced the addition ... New Global Agenda " report to their offering. ... Europe - the 2016 edition is a ... identifies the driving factors coming into play which will influence ... and in the future. It provides a wealth of knowledge ...
Breaking Medicine Technology: