Navigation Links
Scientists Find Molecular Switch Related to Huntington's
Date:12/24/2009

Mouse study holds promise for humans with hereditary disease

THURSDAY, Dec. 24 (HealthDay News) -- Researchers are reporting that they've discovered a molecular switch that appears to play a role in whether Huntington's disease develops in mice.

An estimated one out of every 10,000 Americans suffer from Huntington's disease, which is hereditary and disrupts a person's ability to walk, talk, think clearly and even swallow. There's currently no way to prevent the disease, which typically leads to death within 10 years of diagnosis, or to keep it from worsening, the study authors noted.

Scientists have found that a mutation in a protein called huntingtin causes the disease to develop. But there's still plenty of mystery about how that happens.

"It's unclear how the mutant protein causes age-related and progressive loss of brain cells in patients with Huntington's disease," X. William Yang, an associate professor of psychiatry and biobehavioral sciences at the Semel Institute of Neuroscience and Human Behavior at University of California Los Angeles, said in a news release from the school. He's senior author of a study on the finding that appears in the Dec. 24 issue of the journal Neuron.

In the study, researchers reported that they've gained new insight into how Huntington's develops by examining the process in mice.

"Our study identified a critical molecular switch...," Yang said. "This finding suggests an exciting new avenue to develop therapeutics for Huntington's disease."

More information

The National Institute of Neurological Disorders and Stroke has more information on Huntington's disease.



-- Randy Dotinga



SOURCE: University of California Los Angeles, news release, Dec.
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Stanford scientists identify protein that keeps stem cells poised for action
2. Scientists Spot Source of Hurdle to AIDS Vaccine
3. BioProcess International Launches a New and Improved Website for Biopharmaceutical Managers and Scientists
4. Scientists Link Molecule to Severe Swine Flu
5. Scientists use cell phone records to predict spread of malaria
6. Scientists uncover protective mechanism against liver cancer
7. UNC scientists coordinate study of link between insulin use and cancer in people with diabetes
8. Doctors and Scientists Create New Society to Promote Non-Animal Toxicology Testing Methods
9. NeuroFocus Adds Two More of the Worlds Leading Neuroscientists to its Advisory Board
10. Scripps Research scientists reveal key structure from ebola virus
11. Stand Up To Cancer Funds High-risk/High-reward Cancer Research by 13 Young Scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2015)... HealthPostures, a pioneering ergonomics company that ... the , May 5 - 7, 2015 Minnesota Safety ... the conference include its bestselling TaskMate sit stand solutions. ... 6100 TaskMate Executive. Features of the 6100 TaskMate Executive ... extended platform work surface and supply holders. Weighing 50 ...
(Date:5/2/2015)... Viejo, CA (PRWEB) May 02, 2015 ProText ... exclusively for use in Final Cut Pro X. ProText ... for use in Final Cut Pro X . ... single keyframe with Pixel Film Studios' ProText Kinetic 2. , ... Start by staggering two ProText Kinetic presets in the ...
(Date:5/2/2015)... May 02, 2015 Kare Visits LLC. launched ... for busy caregivers. Kare Visits offers relief for caregivers ... living facilities. According to the Caregiver Action Network, ... average of 20 hours a week caring for an elderly ... cost to hire a nurse, a caregiver is now empowered ...
(Date:5/1/2015)... Caicos Islands, BWI (PRWEB) May 02, 2015 ... website! It is http://www.thevenetiangracebay.com , and it ... it incorporates the stunning white and attractive turquoise hues ... study of Google, sixty seven percent of leisure travelers ... study showed that smartphones were used in the planning ...
(Date:5/1/2015)... (PRWEB) May 01, 2015 TROY Healthcare ... Cerner Southeast Regional User Group (RUG) Conference in Atlanta, ... Southeast Regional User Group Conference provides a forum for ... who support all aspects of electronic medical record operations, ... Cerner software applications. , In addition to sponsoring the ...
Breaking Medicine News(10 mins):Health News:HealthPostures to Appear at the Minnesota Safety and Health Conference 2Health News:HealthPostures to Appear at the Minnesota Safety and Health Conference 3Health News:Pixel Film Studios Announced the Release of Protext Kinetic 2 for FPCX. 2Health News:Chicagoan Seeks to Transform Industry by Launching an Innovative Elderly Care Solution 2Health News:Turks and Caicos Resort, The Venetian on Grace Bay, Launches New Web Presence 2Health News:TROY Healthcare to Exhibit at the Cerner Southeast Regional User Group Conference 2Health News:TROY Healthcare to Exhibit at the Cerner Southeast Regional User Group Conference 3
... own natural alarm clocks which can be set subconsciously just ... conducted by scientists at the University of Lubeck in Germany ... them to anticipate the "stress" of getting up at different ... of the power of thought when it comes to controlling ...
... demanding - or who do shift work - could ... in the US showed that this heavy work was ... babies. ,Jobs which involved long periods of ... significantly linked with premature birth. Physically demanding work was ...
... is implanted permanently in the eye is safe and effective ... alternative for laser operations that correct nearsightedness by reshaping the ... Allan Vukich of the University of Wisconsin School of Medicine ... the results of a multicenter trial of patients who had ...
... serious morning sickness if they are pregnant with a girl, ... Norway between 1977 and 1985 showed there was a greater ... female child. ,Though there were more births of ... of mothers-to-be of girls being admitted to hospital suffering from ...
... and aspirin are equally effective in stroke prevention in the ... stopping platelets from clumping together, while warfarin acts on the ... help prevent blood clots in the brain that lead to ... more effective at preventing stroke, but causes more side effects ...
... self-contained artificial heart suffered bleeding in his brain in the ... latest setback caused swelling and made the patient, Robert Tools, ... said. // ,Robert Tools received the AbioCor mechanical ... the time, he was so ill he had been given ...
Cached Medicine News:Health News:The alarm clock in you 2
(Date:5/1/2015)... , May 1, 2015  Legendary actor and director ... a new PBAFacts campaign designed to educate and encourage ... more about Pseudobulbar Affect (PBA) and to speak with ... an actor has the ability to cry and laugh ... of control experienced by people living with PBA episodes. ...
(Date:5/1/2015)... 2015  Misonix, Inc. (NASDAQ: MSON ), ... and markets innovative therapeutic ultrasonic products for spine ... laparoscopic surgery and other surgical applications, announced today ... third quarter fiscal year 2015 on Thursday, May ... call that same day, Thursday, May 7, 2015, ...
(Date:4/30/2015)... WOODBRIDGE, ON , April 30, 2015 /PRNewswire/ ... a specialty pharmaceutical company with a focus on ... health, announced its operational highlights and financial results ...  All dollar amounts referenced herein are in Canadian ... in 2014 have been significant, with the right ...
Breaking Medicine Technology:Danny Glover Joins PBA Facts Campaign, to Educate and Build Awareness of Pseudobulbar Affect (PBA), a Little Known but Widespread Neurologic Condition 2Danny Glover Joins PBA Facts Campaign, to Educate and Build Awareness of Pseudobulbar Affect (PBA), a Little Known but Widespread Neurologic Condition 3Misonix, Inc. To Report Third Quarter Fiscal Year 2015 Financial Results On Thursday, May 7, 2015 2Pivotal Therapeutics Announces 2014 Financial Results 2Pivotal Therapeutics Announces 2014 Financial Results 3Pivotal Therapeutics Announces 2014 Financial Results 4Pivotal Therapeutics Announces 2014 Financial Results 5Pivotal Therapeutics Announces 2014 Financial Results 6
... MARINO, Calif., June 14, 2011 Viral Genetics, ... to a clinical-stage company. The Company,s two lead ... Metabolic Disruption (MDT) compounds for drug-resistant cancers -- ... or investigator-initiated Investigational New Drug (IND) pathways. An ...
... BSI Group America Inc. (BSI), a leading ... solutions, is pleased to introduce Entropy Software for ... quality management software solution to assist organizations to ... reporting, and improved quality and compliance assurance. Designed ...
Cached Medicine Technology:Viral Genetics Updates HIV/AIDS and Drug Resistant Cancer Research Programs 2Viral Genetics Updates HIV/AIDS and Drug Resistant Cancer Research Programs 3Viral Genetics Updates HIV/AIDS and Drug Resistant Cancer Research Programs 4BSI Introduces Entropy® Software for Healthcare Product Manufacturers 2BSI Introduces Entropy® Software for Healthcare Product Manufacturers 3
... Physician-office® is an internet ... (Solo practice, group practice ... complete their normal duties ... is a front office ...
... is a modular, Electronic Medical Record (EMR) system ... create a patient chart. ChartMaker is an ... M compliant patient notes, medical reports, letters, and ... ChartMaker is designed to be installed in a ...
... original EMR companies, with a wealth and ... With over a decade of clinical and ... design, corporate level training and support, enables ... medical practice to EMR. The unparalleled HL7 ...
... is dedicated to serving the needs ... ultimate tool to,run a better orthopaedic ... records software.,AcerMed's Orthopaedic-Edition EMR software has ... surgeons across the country resulting in ...
Medicine Products: