Navigation Links
Scientists Find Gene Differences in Nonsmokers With Lung Cancer
Date:11/12/2012

MONDAY, Nov. 12 (HealthDay News) -- Three genetic regions associated with increased lung cancer risk in Asian women who have never smoked have been identified by an international team of scientists.

They said their findings provide further proof that the risk of lung cancer among people who never smoked, especially Asian women, may be associated with specific genetic characteristics that distinguish it from lung cancer in smokers.

The researchers analyzed data from 14 studies that included a total of about 14,000 Asian women (6,600 with lung cancer and 7,500 without the disease). The team found that variations at three locations in the genome -- two on chromosome 6 and one on chromosome 10 -- were associated with lung cancer in Asian women who never smoked.

The discovery on chromosome 10 was especially important because it has not been found in previous research, according to the study published online Nov. 11 in the journal Nature Genetics.

"Our study provides strong evidence that common inherited genetic variants contribute to an increased risk of lung cancer among Asian women who have never smoked," study co-author Dr. Nathaniel Rothman, a senior investigator in the division of cancer epidemiology and genetics at the U.S. National Cancer Institute, said in an institute news release.

"These variants may also increase lung cancer risk associated with environmental factors, such as environmental tobacco smoke," he added.

The researchers did not find an association between lung cancer risk in Asian women who had never smoked and variations at a location on chromosome 15 that has been linked with lung cancer risk in smokers. This provides further proof that the genetic variation on chromosome 15 may be smoking related, the authors said in the news release.

The research team also found some evidence that Asian women with one of the newly identified genetic variants may be more vulnerable to the effects of secondhand smoke. But more research is needed to confirm this.

Lung cancer among people who have never smoked is the seventh leading cause of cancer death worldwide, according to the release. Historically, most lung cancer diagnosed among women in Eastern Asia has been among those who never smoked. The three genetic variations identified in this study have not been associated with lung cancer risk in other populations.

More information

The American Cancer Society has more about lung cancer.

-- Robert Preidt

SOURCE: U.S. National Cancer Institute, news release, Nov. 11, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Scientists at IRB BARCELONA discover a key process that allows colon cancer to metastasize
2. Scientists uncover a new pathway that regulates information processing in the brain
3. 2 Scripps Research Institute scientists honored by American Chemical Society
4. Scientists test 5,000 combinations of 100 existing cancer drugs to find more effective treatments
5. Loyola names Junior and Senior Scientists of the Year
6. Scientists find Achilles’ heel of cancer cells
7. UC Davis scientists identify new target for lung cancer treatment
8. Scientists create endless supply of myelin-forming cells
9. Scientists decode software instructions of aggressive leukemia cells
10. Canadian scientists discover cause of high cholesterol
11. Scientists step up hunt for bacterial genes tied to Lyme disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Find Gene Differences in Nonsmokers With Lung Cancer
(Date:2/12/2016)... ... 12, 2016 , ... For Coast Dental dentist Everet Lake, DDS, the smiles ... Terrell Moore shortly before 7 a.m. to volunteer at Friday’s Dentistry from the Heart ... and skills to help hundreds of uninsured and underinsured people receive much-needed dental care. ...
(Date:2/12/2016)... New York, NY (PRWEB) , ... February 12, ... ... latest edition of “Revolutionizing Cancer Care.” , The print component of ... in Chicago, Dallas, Pittsburgh/Cleveland, New York, Washington DC/Baltimore, and Seattle, with a circulation ...
(Date:2/12/2016)... DC (PRWEB) , ... February 12, 2016 , ... ... “Managing High-Cost Drug Categories: Strategies for Health Plans and PBMs,” an upcoming Feb. ... to maintain affordability and access in big-dollar therapeutic categories, such as the $1,000-per-pill ...
(Date:2/12/2016)... ... February 12, 2016 , ... US Sport Camps is ... Legacy Golf Club, located in Norwalk, serves as the host site and directing the ... Randall. , “We have had successful camps in recent years around Des Moines and ...
(Date:2/12/2016)... ... ... Healthcare careers in the medical laboratory, nursing, and in the imaging field topped ... leader Aureus Medical Group during the month of January. Aureus Medical specializes in placing ... in travel and direct hire opportunities in other allied health fields. , The jobs ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... Conn. , Feb. 11, 2016  AfterPill.com is ... to recommend alcohol abstinence for all women who are ... in the U.S. each year and raises the risks ... --> --> According to the Guttmacher ... 70% of women of child-bearing age, who have sex ...
(Date:2/11/2016)... 2016 Wearable posture tracker, ALEX , has taken Kickstarter by storm, crowdfunding over $60,000 ... left to go, ALEX is said to be delivered to backers starting May of this year. ... ... ... Created by NAMU, a team of ...
(Date:2/11/2016)... 2016  Proliant Biologicals is proud to announce the ... manufacturing facility.  The facility is located on the North ... Feilding. Boone , Iowa.  The ... the systems in the U.S. facility, with critical processing ... installations.  --> Boone , ...
Breaking Medicine Technology: