Navigation Links
Scientists Discover 'Ultra-Bad' Cholesterol
Date:5/27/2011

FRIDAY, May 27 (HealthDay News) -- A new, "ultra-bad" form of low-density lipoprotein (LDL) cholesterol has been discovered in people with a high risk for heart disease, according to British researchers.

They found that the cholesterol, called MGmin-LDL, is super-sticky, making it more likely to attach to the walls of arteries and form fatty plaques, which could lead to heart attacks and stroke.

The discovery provides a possible explanation for the increased risk of coronary heart disease in diabetics and could help researchers develop new anti-cholesterol treatments, the researchers suggested.

In the study, which was funded by the British Heart Foundation, University of Warwick researchers created MGmin-LDL in a lab through glycation, which is the adding of sugar groups to normal LDL cholesterol, commonly referred to as "bad" cholesterol. The process changed the cholesterol's shape, making it stickier and more likely to build fatty plaques, narrow arteries and reduce blood flow and turning it into what they called "ultra-bad" cholesterol.

The findings, released online May 26 in Diabetes, could have significant implications for the treatment of coronary heart disease, particularly in older people and those with type 2 diabetes. Specifically, the researchers said, the results of their study shed light on how a common type 2 diabetes drug, metformin, fights heart disease by blocking the transformation of normal LDL into the super-sticky LDL.

"We're excited to see our research leading to a greater understanding of this type of cholesterol, which seems to contribute to heart disease in diabetics and elderly people," the study's lead researcher, Naila Rabbani, an associate professor of experimental systems biology at Warwick Medical School, said in a university news release.

"The next challenge is to tackle this more dangerous type of cholesterol with treatments that could help neutralize its harmful effects on patients' arteries," she said.

More information

The American Heart Association has more on cholesterol.

-- Mary Elizabeth Dallas

SOURCE: University of Warwick, news release, May 27, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Scientists Pinpoint Area of Brain That Fears Losing Money
2. Scientists Discover How HIV Is Transmitted Between Men
3. Prevention Is Key Research Goal for Premature Babies, Scientists Say
4. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
5. Scientists find donut-shaped structure of enzyme involved in energy metabolism
6. Neuroscientists reveal new links that regulate brain electrical activity
7. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. Scientists Spot Genetic Fingerprints of Individual Cancers
10. Scientists Unravel Mysteries of Intelligence
11. MSU scientists develop more effective method of predicting lead-poisoning risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Discover 'Ultra-Bad' Cholesterol
(Date:9/22/2017)... ... September 22, 2017 , ... After a long health ... a new lease on life with assistance from CreditAssociates. CreditAssociates provides debt relief ... with unsecured debt. The senior is one of the satisfied clients who expressed ...
(Date:9/22/2017)... ... September 22, 2017 , ... Happy Living’s mission - to improve the health ... into the entertaining and delicious worlds of theatre and wines. , After watching ... him to turn his play into a book. The Greener The Grass ( https://www.happyliving.com/books/the-greener-the-grass ...
(Date:9/22/2017)... ... September 22, 2017 , ... TopConsumerReviews.com recently ... Native Remedies that helps promote pancreatic health and regulate blood sugar levels ... prescription-based approaches can have negative side effects, and with the changes in today’s ...
(Date:9/22/2017)... ... September 22, 2017 , ... Silicon Valley startup Enke ... the go. Their electric toothbrushes aggressively attack oral bacteria by reducing dental plaque ... Combining leading edge Enke technology with a premium timeless design, they want to ...
(Date:9/22/2017)... ... September 22, 2017 , ... The freshly ... customers’ doorstep. According to Smart Mart, customers can now order vegetable, fruit, snacks, ... and customers can find clothing at discounted prices. Apart from this, Smart Mart ...
Breaking Medicine News(10 mins):
(Date:9/12/2017)... 12, 2017  ValGenesis Inc., the global leader ... pleased to announce the appointment of Dr. ... Board of Directors and Chairman of Advisory Board ... science companies to manage their entire validation lifecycle ... in this process. Furthermore, ValGenesis VLMS enables rigorous ...
(Date:9/7/2017)... Calif. , Sept. 7, 2017  For nearly two decades, New ... in the Assisted Reproduction Insurance industry. Today, New Life Agency announces a ... medications. ... http://pharmacarecard.com/ (PRNewsfoto/PharmaCareCard) ... ...
(Date:9/6/2017)... , Sept. 6, 2017  Robert G. Szewc, ... Pinnacle Professional Member in recognition of his contributions to ... serves as a Nephrologist at the practice of Kidney ... medicine, kidney care and hypertension solutions. He has worked ... years of career experience, as well as expertise in ...
Breaking Medicine Technology: