Navigation Links
Scientists Discover Trigger for Autoimmune Diseases
Date:12/22/2008

Self-attacking, dormant cells switch 'on' in those with lupus, rheumatoid arthritis

MONDAY, Dec. 22 (HealthDay News) -- Healthy adults have potential autoimmune disease-causing cells, but these cells stay in an "off" state, a U.S. study shows.

Immune cells that attack the body cause autoimmune diseases such as lupus and rheumatoid arthritis (RA). Whether the switched-off cells in healthy adults are true precursors of the self-attacking immune cells and, if so, what prevents them from causing disease in certain people, isn't known, the researchers said.

J. Andrew Duty, of the Oklahoma Medical Research Foundation, and colleagues found that anergic (dormant) autoimmune disease-causing cells account for 2.5 percent of immune B-cells circulating in the blood of healthy adults.

These anergic cells don't appear to cause problems in healthy adults, but did produce self-reactive antibodies when exposed to a strong stimulus in lab experiments. This means these anergic cells may contain the precursors for the self-attacking B-cells in patients with autoimmune disease, the researchers said.

In previously healthy people, anergy may somehow break down and allow self-attacking B-cells to cause autoimmune disease.

The study was published in the Dec. 22 online issue of The Journal of Experimental Medicine.

More information

The U.S. National Women's Health Information Center has more about autoimmune diseases.



-- Robert Preidt



SOURCE: Rockefeller University Press, news release, Dec. 22, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

0

GOOD

Page: 1

Related medicine news :

1. Scientists Spot Key to Cystic Fibrosis Infections
2. Scientists, Physicians, Health, and Environmental Justice Advocates to New Obama EPA Director: We Look Forward to Toxic Chemical Regulatory Reform
3. Seven life scientists get research boost to set up in Europe
4. UC San Diego scientists developing brain imaging methods for studying natural human behavior
5. Scientists ID Enzyme Causing Brain Cell Death
6. NASA scientists provide update on existing remote sensing technology programs and new projects
7. Scientists ID Protein Aiding Breast Cancer Spread
8. UCLA scientists prove endothelial cells give rise to blood stem cells
9. Scientists at CSHL uncover new RNA processing mechanism and a new class of small RNAs
10. CSHL scientists show how a protein that determines cell polarity prevents breast cancer
11. Carnegie Mellon scientists offer explanation for face blindness
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Discover Trigger for Autoimmune Diseases
(Date:5/22/2013)... (PRWEB) May 22, 2013 The Muscular ... against muscular dystrophy at the annual Charlotte Muscle Team ... to help Charlotte-area families living with muscle disease. ... year's event to support MDA families,” said MDA Divisional ... who were partnered with a "Buddy" to make their ...
(Date:5/22/2013)... 22, 2013 Zensah® Compression Apparel released ... article titled "Breast pain while running affects ... could help." According to the article, a British ... substantial amount suffer from breast pain while running but ... the issue. , Zensah emphasizes the importance for ...
(Date:5/22/2013)... study shows there is a gender gap when it ... one that does not appear to exist in ... had higher levels of self-regulation than boys. Self-regulation is ... impulses, follow directions, and persist on a task. It ... in past studies by Oregon State University researchers. ...
(Date:5/22/2013)... 22, 2013 People in the United States ... to water shortages. In much of the world, water shortages ... advocate, Sharon Kleyne. She warns against taking water for granted ... is available so easily in the United States. , Sharon ... Water radio show, heard live or by podcast on World ...
(Date:5/22/2013)... New York (PRWEB) May 22, 2013 ... version of the DePuy Pinnacle Hip Replacement System continue ... Texas Federal Court, Bernstein Liebhard LLP reports. According ... directed DePuy Orthopaedics to produce monitoring reports associated with ... the company’s medical device marketing practices. Plaintiffs maintained ...
Breaking Medicine News(10 mins):Health News:Charlotte Muscle Team Event Raises $300,000 in the Fight Against Muscle Disease 2Health News:Zensah® Comments on New York Daily News Article Examining How Better Sports Bra Could Help Women Marathoners 2Health News:Zensah® Comments on New York Daily News Article Examining How Better Sports Bra Could Help Women Marathoners 3Health News:'Boys will be boys' in US, but not in Asia 2Health News:'Boys will be boys' in US, but not in Asia 3Health News:Water Advocate Sharon Kleyne Announces Water Conservation Appreciation 2Health News:DePuy Pinnacle Lawsuit News: Bernstein Liebhard LLP Notes New Order in Federal Pinnacle Litigation Requiring Production of Monitoring Reports from Federal Investigation 2Health News:DePuy Pinnacle Lawsuit News: Bernstein Liebhard LLP Notes New Order in Federal Pinnacle Litigation Requiring Production of Monitoring Reports from Federal Investigation 3
... adherence counseling around the time of HIV treatment initiation ... sub-Saharan Africa, according to a recent study in ... of Global Health at University of Washington, who works ... Nairobi, Kenya. The study published March 1 also ...
... By Alan Mozes HealthDay Reporter , WEDNESDAY, March 2 ... may claim bragging rights. But when it comes to the average ... to the north, a new study of adult obesity rates in ... third of all Americans are now obese, beating out Canada by ...
... bright yellow spice from south Asia belonging to the ... and ancient wisdom suggests that it,s also good for ... Aviv University researchers have discovered that turmeric,s active ingredient ... anti-inflammatory drugs used to fight colon cancer when used ...
... WEDNESDAY, March 2 (HealthDay News) -- Hearing loss affects nearly ... than whites to have hearing problems, a new study shows. ... aged 70 and older who took part in the 2005-06 ... them had hearing loss that ranged from mild to severe. ...
... Reporter , TUESDAY, March 1 (HealthDay News) -- Both ... the risk for breast cancer among postmenopausal women, new ... or no connection between breast cancer and smoking, as ... surfacing for the first time, experts noted. "The ...
... By Steven Reinberg HealthDay Reporter , TUESDAY, ... that the U.S. Food and Drug Administration approves medical ... Many heart-related devices win FDA approval without being adequately ... so. This means that heart valves, pacemakers, ...
Cached Medicine News:Health News:Study in PLoS: Intensive adherence counseling to HIV treatment improves patient outcomes 2Health News:In Battle of the Bulge, Canada Trumps U.S. 2Health News:In Battle of the Bulge, Canada Trumps U.S. 3Health News:In Battle of the Bulge, Canada Trumps U.S. 4Health News:Fighting cancer at your local Indian restaurant 2Health News:Study Finds Smoking Linked to Breast Cancer Risk 2Health News:Study Finds Smoking Linked to Breast Cancer Risk 3Health News:Heart Devices Not Tested Enough in Women: Study 2Health News:Heart Devices Not Tested Enough in Women: Study 3
(Date:5/22/2013)... , May 22, 2013  Heska Corporation (NASDAQ: HSKA, "Heska" ... specialty products, announced today that the Company will present at ... 29, 2013 at the Le Parker Meridian hotel, 119 W. ... . The presentation is scheduled to begin at 2:15 ... About Heska Heska Corporation (NASDAQ: HSKA ...
(Date:5/22/2013)... Attorney Advertising -- Bronstein, Gewirtz & Grossman, ... purchasers of the securities of AMAG Pharmaceuticals, Inc. ... investigation focuses on whether the Company and its ... May 22, 2013, Shares of AMAG dropped $2.69 ... announced in regulatory filing that it has been ...
(Date:5/22/2013)... , May 22, 2013 JenaValve Technology, Inc., ... valve implantation (TAVI) systems for the treatment of aortic valve ... J enaValve Eval U ation of Long Term P ... S E vere Ao R tic Stenosis (JUPITER) Registry at ... post-market registry to evaluate five-year long term safety and effectiveness ...
Breaking Medicine Technology:Bronstein, Gewirtz & Grossman, LLC Announces Investigation of AMAG Pharmaceuticals, Inc. 2First Results Of The JUPITER Registry On Long Term Performance And Safety Of The Transapical JenaValve TAVI System 2First Results Of The JUPITER Registry On Long Term Performance And Safety Of The Transapical JenaValve TAVI System 3First Results Of The JUPITER Registry On Long Term Performance And Safety Of The Transapical JenaValve TAVI System 4
The Codman anterior cervical plate is designed for immediate internal fixation of the cervical spine following bone grafting procedures....
... system is a family of plates that ... for consistent, reliable fixation of plate to ... backout. This innovative design eliminates the need ... your screws and the swivel ring automatically ...
... a compact and quiet, yet powerful ... psi/8 bar, it provides more power ... noticeable noise reduction. A small, compact ... enhanced ergonomic handpiece to produce a ...
The stereotactic frame has been specifically designed for a radiosurgery procedure and can be used instead of traditional expensive frames....
Medicine Products: