Navigation Links
Scientists Create New Means to Study Disease Origins
Date:12/24/2008

Availability of rat stem cells may help link genes to human disorders,,

WEDNESDAY, Dec. 24 (HealthDay News) -- The first embryonic stem (ES) cells from rats have been derived by University of Southern California researchers, who said their success will enable the creation of far more effective animal models to study a wide range of human diseases.

"This is a major development in stem cell research because we know that rats are much more closely related to humans than mice in many aspects of biology," principal investigator Qi-Long Ying, an assistant professor of cell and neurobiology at the Keck School of Medicine, said in a university news release. "The research direction of many labs around the world will change because of the availability of rat ES cells."

The ability to derive rat ES cells advances efforts to create rats for use in biomedical research that are genetically modified to lack one or more genes. The ability to observe what happens to an animal when specific genes are removed helps scientists pinpoint the function of genes and whether they're associated with specific diseases.

"The availability of rat ES cells will greatly facilitate the creation of rat models for the study of different human diseases, such as cancer, diabetes, high blood pressure, addiction and autoimmune diseases," said Ying, who is also a researcher at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at the university.

The first ES cell lines from mice were created in 1981, and researchers have long been trying to establish rat ES cells. But conventional methods developed for deriving mouse ES cells didn't work in rats. The research team finally found a laboratory-based way to grow rat stem cells indefinitely in the primitive embryonic state.

The research appears in the Dec. 26 issue of Cell.

In another study published in the same issue of the journal, a team led by researchers at the University of Cambridge in England report similar findings. This provides independent verification that authentic ES cells can be established from rats.

More information

The U.S. National Institutes of Health has more about stem cells.



-- Robert Preidt



University of Southern California, news release, Dec. 24, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Scientists reveal structure of new botulism nerve toxin subtype
2. Scientists Discover Trigger for Autoimmune Diseases
3. Scientists Spot Key to Cystic Fibrosis Infections
4. Scientists, Physicians, Health, and Environmental Justice Advocates to New Obama EPA Director: We Look Forward to Toxic Chemical Regulatory Reform
5. Seven life scientists get research boost to set up in Europe
6. UC San Diego scientists developing brain imaging methods for studying natural human behavior
7. Scientists ID Enzyme Causing Brain Cell Death
8. NASA scientists provide update on existing remote sensing technology programs and new projects
9. Scientists ID Protein Aiding Breast Cancer Spread
10. UCLA scientists prove endothelial cells give rise to blood stem cells
11. Scientists at CSHL uncover new RNA processing mechanism and a new class of small RNAs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2017)... Durham, NC (PRWEB) , ... March 30, 2017 ... ... professionals, will host the live audio conference “ Preventing Hospital Readmissions Through Discharge ... April 12, 2017 at 1:00 pm ET. This conference discusses strategies to prevent ...
(Date:3/29/2017)... ... March 29, 2017 , ... In the United States alone, up ... year develop other types of metastatic brain tumors(3). Though most meningiomas are benign, metastatic ... focus on finding more effective treatment options, the San Diego Gamma Knife Center ...
(Date:3/29/2017)... ... March 30, 2017 , ... CHARM CITY RUN WELCOMES MERCY MEDICAL CENTER AS ... Medical Center will serve as the official title sponsor of the Baltimore Women’s Classic, ... 2017, thousands of women will walk or run the course around the Baltimore Inner ...
(Date:3/29/2017)... ... March 29, 2017 , ... Wells Pharmacy ... attending prescribers at the upcoming World Congress, in Hollywood Florida April 6-8, 2017. ... recognized as the visionary leader in the training of physicians, scientists, and members ...
(Date:3/29/2017)... ... 29, 2017 , ... Patients interested in receiving quick and ... Jamie Cameron, with or without a referral. The FASTBRACES system is valued for ... each patient’s case, treatment with the FASTBRACES system could be completed in 120 ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)... DUBLIN , Mar. 29, 2017 ... "Intraoperative Neuromonitoring (IONM) Market Size & Forecast By Type (Insource ... - 2025" report to their offering. ... The global Intraoperative ... by 2025. The intraoperative neuromonitoring market is anticipated to witness ...
(Date:3/29/2017)... March 29, 2017 Global intravenous (IV) iron and ... by 2021, growing at a CAGR of 5%. ... a doctor to treat anemia or other iron deficiencies. Oral ... the body. However, in some cases, oral administrations are not ... intravenous (IV) iron therapy comes into the picture. ...
(Date:3/29/2017)... 29, 2017 Today, CVS Health officials (NYSE: ... , Department of Public Health Director Gerd Clabaugh ... in announcing the availability of the opioid overdose-reversal medicine ... Iowa.  CVS Health has established a standing order with physicians ... to expand access to the medication in the state.   ...
Breaking Medicine Technology: