Navigation Links
Scientists Create Breast Cancer Survival Predictor

WEDNESDAY, April 17 (HealthDay News) -- Columbia University scientists have developed a new model to predict breast cancer survival, and they say their work could lead to improved diagnosis and prognosis for all types of cancers.

In earlier work, the researchers identified certain gene signatures that are present in nearly identical form in many cancer types. Using that information, they developed a model that showed that these gene signatures, when properly combined, were strong indicators for breast cancer survival.

The findings appear in the April 17 issue of the journal Science Translational Medicine.

"These signatures manifest themselves in specific genes that are turned on together in the tissues of some patients in many different cancer types," team leader Dimitris Anastassiou, a professor in electrical engineering and a member of the Columbia Initiative in Systems Biology, said in a university news release.

"And if these general cancer signatures are useful in breast cancer ... then why not in other types of cancer as well?" he said. "I think that the most significant -- and exciting -- implication of our work is the hope that these signatures can be used for improved diagnostic, prognostic and, eventually, therapeutic products, applicable to multiple cancers."

There are many biomarker products that look at specific genes in cancer biopsy samples in order to help doctors determine whether a particular treatment will be appropriate for a patient.

"Some of these genes are related to those in our signatures, so it's worth finding out if replacing such genes with our precise 'pan-cancer' signatures will improve the accuracy of these products," Anastassiou said.

The new model developed by the Columbia researchers won the Sage Bionetworks/DREAM Breast Cancer Prognosis Challenge.

More information

The U.S. National Cancer Institute has more about breast cancer.

-- Robert Preidt

SOURCE: Columbia University, news release, April 17, 2013

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Molecule treats leukemia by preventing cancer cell repair, Jackson Laboratory scientists report
2. Scientists map elusive 3-D structure of telomerase enzyme, key actor in cancer, aging
3. Scientists discover gene mutation that causes children to be born without spleen
4. Unusual suspect: Hopkins scientists find second fiddle proteins role in Type 2 diabetes
5. Polio eradication is achievable by 2018 and urgent, declare 400+ global scientists
6. Scientists create phantom sensations in non-amputees
7. Scientists Map Genome for Dutch Elm Disease Fungus
8. Could Scientists Peek Into Your Dreams?
9. CWRU-led scientists build material that mimics squid beak
10. Singapore clinician-scientists identify new type of deadly lymphoma
11. Kessler Foundation scientists receive Consortium of MS Centers grant to study emotional processing
Post Your Comments:
Related Image:
Scientists Create Breast Cancer Survival Predictor
(Date:11/25/2015)... ... November 25, 2015 , ... For the first time, ... Two Organizations, One Beat ” campaign. The partnership between the two groups began in ... in MAP International’s cause. , MAP International was founded in 1954 and is an ...
(Date:11/25/2015)... ... 25, 2015 , ... Dental professionals who would like to become more proficient ... attend Dr. Mark Iacobelli’s Advanced Implant Mentoring (AIM) CE course. Courses will be held ... the co-founders of Advanced Implant Mentoring (AIM), Dr. Iacobelli and Dr. D’Orazio are proud ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... The McHenry ... a recent successful appellate decision obtained by Attorneys Francisco J. Botto and Alex C. ... v. Illinois Workers’ Compensation Comm’n, 2015 IL App (2d) 130884WC. , According to court ...
(Date:11/25/2015)... ... November 25, 2015 , ... SCOTTSDALE, AZ) - Today, ... specializing in both surgical and non-surgical treatments, announced the expansion of his private ... Plastic Surgery. , Highly trained and nationally recognized for his natural approach, ...
(Date:11/25/2015)... ... November 25, 2015 , ... In an ongoing Clinical ... Center (RMC) in Chicago, IL, UV Angel is evaluating the efficacy of its product ... intensive care units (totaling 30 beds) from May 2014 through October 2015 at a ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... and Markets ( ) has announced the addition of ... - Rise in Cardiac Disorders and Growing Awareness among People ... Boston scientific and others. ... others. --> The market is dominated by ... scientific and others. Asia ...
(Date:11/26/2015)... 26, 2015 ... "2016 Future Horizons and Growth Strategies ... Market: Supplier Shares, Country Segment Forecasts, Competitive ... offering. --> ) has ... Future Horizons and Growth Strategies in the ...
(Date:11/26/2015)... 26, 2015 ) ... Administration of High Viscosity Drugs" report to ... announced the addition of the "Self Administration ... offering. --> Research and Markets ( ... "Self Administration of High Viscosity Drugs" ...
Breaking Medicine Technology: