Navigation Links
Scientists Create Breast Cancer Survival Predictor
Date:4/17/2013

WEDNESDAY, April 17 (HealthDay News) -- Columbia University scientists have developed a new model to predict breast cancer survival, and they say their work could lead to improved diagnosis and prognosis for all types of cancers.

In earlier work, the researchers identified certain gene signatures that are present in nearly identical form in many cancer types. Using that information, they developed a model that showed that these gene signatures, when properly combined, were strong indicators for breast cancer survival.

The findings appear in the April 17 issue of the journal Science Translational Medicine.

"These signatures manifest themselves in specific genes that are turned on together in the tissues of some patients in many different cancer types," team leader Dimitris Anastassiou, a professor in electrical engineering and a member of the Columbia Initiative in Systems Biology, said in a university news release.

"And if these general cancer signatures are useful in breast cancer ... then why not in other types of cancer as well?" he said. "I think that the most significant -- and exciting -- implication of our work is the hope that these signatures can be used for improved diagnostic, prognostic and, eventually, therapeutic products, applicable to multiple cancers."

There are many biomarker products that look at specific genes in cancer biopsy samples in order to help doctors determine whether a particular treatment will be appropriate for a patient.

"Some of these genes are related to those in our signatures, so it's worth finding out if replacing such genes with our precise 'pan-cancer' signatures will improve the accuracy of these products," Anastassiou said.

The new model developed by the Columbia researchers won the Sage Bionetworks/DREAM Breast Cancer Prognosis Challenge.

More information

The U.S. National Cancer Institute has more about

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Molecule treats leukemia by preventing cancer cell repair, Jackson Laboratory scientists report
2. Scientists map elusive 3-D structure of telomerase enzyme, key actor in cancer, aging
3. Scientists discover gene mutation that causes children to be born without spleen
4. Unusual suspect: Hopkins scientists find second fiddle proteins role in Type 2 diabetes
5. Polio eradication is achievable by 2018 and urgent, declare 400+ global scientists
6. Scientists create phantom sensations in non-amputees
7. Scientists Map Genome for Dutch Elm Disease Fungus
8. Could Scientists Peek Into Your Dreams?
9. CWRU-led scientists build material that mimics squid beak
10. Singapore clinician-scientists identify new type of deadly lymphoma
11. Kessler Foundation scientists receive Consortium of MS Centers grant to study emotional processing
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Create Breast Cancer Survival Predictor
(Date:8/29/2015)... ... ... The popular television program VOICES IN AMERICA, hosted by legendary star of ... an entire short segment to the subject of diabetes. Diabetes is a debilitating health ... basis, but recent advancements in medical science may prove to be a significant breakthrough ...
(Date:8/28/2015)... ... August 28, 2015 , ... Approximately 2,000 ... Zoo to celebrate children helping children, a thank you to the many creative ... have contributed to the United Methodist initiative to end malaria deaths. , The ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... Position and Best Practices for Compliance, **Presented by FDAnews and GessNet**, Oct. ... by internationally renowned expert Fubin Wu, has been specifically designed to provide ...
(Date:8/28/2015)... ... August 28, 2015 , ... Saint Petersburg, ... protein with zero fat, carbs, sugar, gluten, lactose or caffeine in a convenient ... the 2015 SupplySide CPG Editor’s Choice Awards. , Five consumer packaged goods (CPG) ...
(Date:8/28/2015)... ... 2015 , ... The Nashville Business Journal recently announced its ... Mr. Troy Mizell, Chairman of the Board at MyGenetx, is one of ... Awards will recognize Nashville military veterans who, through their professional and personal efforts, ...
Breaking Medicine News(10 mins):Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 3Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 2Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 3Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 4Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 5Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 2Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 3Health News:MyGenetx Board Member Receives Veterans Award 2
... (Linc) Sonenshein, PhD, professor of molecular biology and microbiology ... the genetics and molecular microbiology program faculties at the ... been awarded the distinction of AAAS Fellow. ... AAAS members by their peers. Fellows are awarded because ...
... HealthDay Reporter , THURSDAY, Jan. 13 (HealthDay News) -- ... your teen,s stomach tied up in knots, a simple intervention ... research, published in the Jan. 14 issue of Science ... their test anxiety and fears just before a test, their ...
... Des Plaines, Ill. (Jan. 13, 2011) The American ... now a 2nd-year medical student at the University of ... Award recipient. The work of Salinas, one of 10 ... "outstanding" by the organization,s distinguished Scientific Advisory Council. ...
... Steven Reinberg HealthDay Reporter , THURSDAY, Jan. 13 ... epidemic, new federal guidelines proposed Thursday focus on making school ... of Agriculture (USDA), would be the first such changes in ... more fruits and vegetables to school cafeteria fare. "For ...
... that put them behind the wheelin a driving simulator, with ... conclusion of a new article published in Current Directions ... Psychological Science. Older people are at much higher ... provinces test older drivers, hoping to get the riskiest drivers ...
... NY, January 13, 2011Twenty years of mortality data from counties ... living at higher altitudes may be a risk factor for ... print in High Altitude Medicine & Biology , a ... is available free online. Barry Brenner, MD, PhD, ...
Cached Medicine News:Health News:Tufts researcher elected 2010 AAAS Fellow for work in superbugs and heat-stable vaccines 2Health News:Write Your Test Stress Away 2Health News:Write Your Test Stress Away 3Health News:ABTA names Ryan Salinas outstanding '10 summer medical student fellow 2Health News:U.S. Aims to Make School Lunches Healthier 2Health News:U.S. Aims to Make School Lunches Healthier 3Health News:Driving simulators help older adults improve their road skills 2
(Date:8/27/2015)... Calif. , Aug. 27, 2015 DURECT ... is scheduled to present at three upcoming healthcare conferences.  ... President and CEO, will present at the Rodman & ... a.m. Eastern time. The conference is being held at ... City . A live audio webcast of the ...
(Date:8/27/2015)... 27, 2015  Eli Lilly and Company (NYSE: ... Conference on Thursday, September 17, 2015. Sue Mahony ... Oncology and Richard Gaynor , M.D., senior vice ... Oncology, will participate in a fireside chat at 3:30 ... audio webcast will be available on the "Webcasts & ...
(Date:8/27/2015)... Ga. , Aug. 27, 2015  MiMedx Group, ... medicine company utilizing human amniotic tissue and patent-protected ... therapies for the Wound Care, Surgical, Orthopedic, Spine, ... responded today and corrected the multiple inaccuracies in ... Foundation ("MTF") regarding the recent rulings from the ...
Breaking Medicine Technology:DURECT to Participate in Upcoming Healthcare Conferences 2Lilly to Participate in Morgan Stanley Global Healthcare Conference 2MiMedx Corrects Inaccuracies In MTF Press Release Regarding The Recent Rulings From The Patent Trial And Appeal Board 2MiMedx Corrects Inaccuracies In MTF Press Release Regarding The Recent Rulings From The Patent Trial And Appeal Board 3MiMedx Corrects Inaccuracies In MTF Press Release Regarding The Recent Rulings From The Patent Trial And Appeal Board 4
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
... 5mm Instrument is a sterile, single ... 5mm diameter insulated shaft. It is ... surgical trocars and FLEXIPATH flexible surgical ... the handle rotates the shaft 360 ...
... features including aspiration holes and additional ... procedures requiring precise dissection with decreased ... suction demands. ,Flexible design options ... nonretractable electrodes and multiple tip designs. ...
... including aspiration holes and additional electrode ... requiring precise dissection with decreased risk ... demands. ,Flexible design options allow ... electrodes and multiple tip designs. Optimize ...
Medicine Products: