Navigation Links
Scientists Create Breast Cancer Survival Predictor
Date:4/17/2013

WEDNESDAY, April 17 (HealthDay News) -- Columbia University scientists have developed a new model to predict breast cancer survival, and they say their work could lead to improved diagnosis and prognosis for all types of cancers.

In earlier work, the researchers identified certain gene signatures that are present in nearly identical form in many cancer types. Using that information, they developed a model that showed that these gene signatures, when properly combined, were strong indicators for breast cancer survival.

The findings appear in the April 17 issue of the journal Science Translational Medicine.

"These signatures manifest themselves in specific genes that are turned on together in the tissues of some patients in many different cancer types," team leader Dimitris Anastassiou, a professor in electrical engineering and a member of the Columbia Initiative in Systems Biology, said in a university news release.

"And if these general cancer signatures are useful in breast cancer ... then why not in other types of cancer as well?" he said. "I think that the most significant -- and exciting -- implication of our work is the hope that these signatures can be used for improved diagnostic, prognostic and, eventually, therapeutic products, applicable to multiple cancers."

There are many biomarker products that look at specific genes in cancer biopsy samples in order to help doctors determine whether a particular treatment will be appropriate for a patient.

"Some of these genes are related to those in our signatures, so it's worth finding out if replacing such genes with our precise 'pan-cancer' signatures will improve the accuracy of these products," Anastassiou said.

The new model developed by the Columbia researchers won the Sage Bionetworks/DREAM Breast Cancer Prognosis Challenge.

More information

The U.S. National Cancer Institute has more about breast cancer.

-- Robert Preidt

SOURCE: Columbia University, news release, April 17, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Molecule treats leukemia by preventing cancer cell repair, Jackson Laboratory scientists report
2. Scientists map elusive 3-D structure of telomerase enzyme, key actor in cancer, aging
3. Scientists discover gene mutation that causes children to be born without spleen
4. Unusual suspect: Hopkins scientists find second fiddle proteins role in Type 2 diabetes
5. Polio eradication is achievable by 2018 and urgent, declare 400+ global scientists
6. Scientists create phantom sensations in non-amputees
7. Scientists Map Genome for Dutch Elm Disease Fungus
8. Could Scientists Peek Into Your Dreams?
9. CWRU-led scientists build material that mimics squid beak
10. Singapore clinician-scientists identify new type of deadly lymphoma
11. Kessler Foundation scientists receive Consortium of MS Centers grant to study emotional processing
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Create Breast Cancer Survival Predictor
(Date:5/25/2016)... ... May 25, 2016 , ... For more than fifty years, we've suffered whiplash as each new ... to conform to the latest nutritional advice – advice that was supposed to keep us ... 2 in 3 American adults are considered to be overweight and more than 1 in ...
(Date:5/25/2016)... ... ... Researchers from SUNY State College of Optometry won the Award for Best ... and human attention. The article, VEP and Human Attention: Translation from Laboratory to ... Vision Testing System (Diopsys, Inc., Pine Brook, NJ) to record visual evoked potentials ...
(Date:5/25/2016)... ... May 25, 2016 , ... Stern Environmental Group , of Secaucus, New ... branded as Stern’s Real Time Monitoring (RTM) Device. Stern Environmental Group will ... motel industry, colleges for use in dormitories, shelters, and nursing homes for real time ...
(Date:5/24/2016)... , ... May 24, 2016 , ... ... its inaugural health care blockchain event, Distributed: Health, to be held in Nashville, ... downtown Symphony Center. , A 24-hour Hackathon preceding the event will host teams ...
(Date:5/24/2016)... ... May 24, 2016 , ... Women's Excellence announces ... Jordan is a Certified Nurse Midwife who was born and raised in Michigan. ... on to complete her masters degree from the University of Mexico. Roberta is ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... , May 24, 2016 ... doble terapia del mundo, introduce catéteres para la ... OrbusNeich, una compañía global especializada en el ... ha expandido su cartera incluyendo productos para tratar ... y Scoreflex™ PTA son los dispositivos de primera ...
(Date:5/23/2016)... May 23, 2016 According ... Equipment Market by Product (Wheelchair, Scooters, Medical Beds, ... Care, Critical Care, Wound), Accessories (Lifting, Transfer) & ... 2021", published by MarketsandMarkets, the patient handling equipment ... by 2021 at a CAGR of 10.5% during ...
(Date:5/23/2016)... 2016 Clarifying Vision - Prospects ... and Vision Care What can be expected ... to grow at the fastest rates? This visiongain ... data, trends, opportunities and prospects. ,Our ... the most lucrative areas in the industry and the ...
Breaking Medicine Technology: