Navigation Links
Scientists Create Breast Cancer Survival Predictor

WEDNESDAY, April 17 (HealthDay News) -- Columbia University scientists have developed a new model to predict breast cancer survival, and they say their work could lead to improved diagnosis and prognosis for all types of cancers.

In earlier work, the researchers identified certain gene signatures that are present in nearly identical form in many cancer types. Using that information, they developed a model that showed that these gene signatures, when properly combined, were strong indicators for breast cancer survival.

The findings appear in the April 17 issue of the journal Science Translational Medicine.

"These signatures manifest themselves in specific genes that are turned on together in the tissues of some patients in many different cancer types," team leader Dimitris Anastassiou, a professor in electrical engineering and a member of the Columbia Initiative in Systems Biology, said in a university news release.

"And if these general cancer signatures are useful in breast cancer ... then why not in other types of cancer as well?" he said. "I think that the most significant -- and exciting -- implication of our work is the hope that these signatures can be used for improved diagnostic, prognostic and, eventually, therapeutic products, applicable to multiple cancers."

There are many biomarker products that look at specific genes in cancer biopsy samples in order to help doctors determine whether a particular treatment will be appropriate for a patient.

"Some of these genes are related to those in our signatures, so it's worth finding out if replacing such genes with our precise 'pan-cancer' signatures will improve the accuracy of these products," Anastassiou said.

The new model developed by the Columbia researchers won the Sage Bionetworks/DREAM Breast Cancer Prognosis Challenge.

More information

The U.S. National Cancer Institute has more about breast cancer.

-- Robert Preidt

SOURCE: Columbia University, news release, April 17, 2013

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Molecule treats leukemia by preventing cancer cell repair, Jackson Laboratory scientists report
2. Scientists map elusive 3-D structure of telomerase enzyme, key actor in cancer, aging
3. Scientists discover gene mutation that causes children to be born without spleen
4. Unusual suspect: Hopkins scientists find second fiddle proteins role in Type 2 diabetes
5. Polio eradication is achievable by 2018 and urgent, declare 400+ global scientists
6. Scientists create phantom sensations in non-amputees
7. Scientists Map Genome for Dutch Elm Disease Fungus
8. Could Scientists Peek Into Your Dreams?
9. CWRU-led scientists build material that mimics squid beak
10. Singapore clinician-scientists identify new type of deadly lymphoma
11. Kessler Foundation scientists receive Consortium of MS Centers grant to study emotional processing
Post Your Comments:
Related Image:
Scientists Create Breast Cancer Survival Predictor
(Date:11/28/2015)... ... 28, 2015 , ... StatRad , a leading provider ... and Claude Hooton to its board of directors. The announcement comes as the ... Annual Meeting and continues to strategically transform its focus from being a teleradiology ...
(Date:11/28/2015)... ... 2015 , ... Pixel Film Studios is back again with ProPanel: Pulse ... are endless. Users have full control over angle of view, speed method, start point, ... sure to get heads to turn. , ProPanel: Pulse offers fully customizable pulsating shape ...
(Date:11/27/2015)... ... 2015 , ... According to an article published November 15th by ... handling security in light of the recent terrorist attacks in Paris, other cities are ... an attack from reaching U.S. soil. Especially around special events that may be high-profile ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... filthy the toilets were," said an inventor from Hillside, N.J. "Many people catch ... seat cover so that individuals will always be protected from germs." , He ...
(Date:11/27/2015)... ... 2015 , ... MPWH, the No.1 Herpes-only dating community in the world, revealed that over 50% ... More than 3.7 billion people under the age of 50 – or 67% of the ... first global estimates of HSV-1 infection . , "The data shocks us highly!" said ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... , Nov. 27, 2015 Research and Markets ... "Global Intrauterine Devices Market 2015-2019" report to ... --> In this report, the author the present ... market for 2015-2019. To calculate the market size, the ... type of products: Hormonal IUDs and copper IUDs. The ...
(Date:11/26/2015)... the Netherlands , November 26, 2015 ... A new combination approach blends immunotherapy with ... A new combination approach blends immunotherapy with Bremachlorin-photodynamic ... A new combination approach blends immunotherapy with Bremachlorin-photodynamic ... the Netherlands has found that immunotherapy can ...
(Date:11/26/2015)... Nov. 26, 2015 Research and Markets ... the "2016 Future Horizons and Growth Strategies ... Supplier Shares, Country Segment Forecasts, Competitive Intelligence, Emerging ... --> --> This ... the Japanese therapeutic drug monitoring market, including emerging ...
Breaking Medicine Technology: