Navigation Links
Scientists Create Autism-Like Traits in Mice
Date:3/21/2011

MONDAY, March 21 (HealthDay News) -- Scientists report that mutating a single gene produced mice with two of the most common autism traits, a finding they say could one day lead to the development of drugs to treat autism.

Currently, there are no effective drugs to treat the disorder.

Mutating the shank3 gene led to compulsive repetitive behavior and avoidance of social interaction in the mice, apparently caused by impaired communication between brain cells, said the researchers at Duke University and the McGovern Institute for Brain Research at the Massachusetts Institute of Technology.

The shank3 gene has been implicated in human autism.

The study was published online March 20 in Nature.

"We now have a very robust model with a known cause for autistic-like behaviors," senior author Guoping Feng, a professor of brain and cognitive sciences at MIT, said in a McGovern Institute news release. "We can figure out the neural circuits responsible for these behaviors, which could lead to novel targets for treatment."

The genetically altered mice also provide a way to assess experimental autism drugs before they're tested in humans.

Scientists acknowledge that research involving animals often fails to result in beneficial treatments for humans.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about autism.

-- Robert Preidt

SOURCE: McGovern Institute for Brain Research, news release, March 20, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Scientists find candidate for new TB vaccine
2. Scientists find a key to maintaining our DNA
3. Scientists ID possible biomarker to gauge Alzheimers prognosis, effect of therapies
4. Scientists identify molecule that can increase blood flow in vascular disease
5. Nottingham scientists identify trigger in cat allergy
6. MIT scientists identify new H1N1 mutation that could allow virus to spread more easily
7. Scripps Research and MIT scientists discover class of potent anti-cancer compounds
8. Scientists find key mechanism of childhood respiratory disease
9. New weight loss discovery by Harvard scientists moves us closer to the Pill for obesity
10. Scientists Link 13 New Gene Regions to Heart Disease Risk
11. Scientists Use Stem Cells, Skin Cells to Create Brain Cells Lost to Alzheimers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2017)... (PRWEB) , ... July 21, 2017 , ... ... Philadelphia and Theater of Witness , was awarded a $300,000 grant ... humanities program which fosters empathy, comfort with ambiguity and the recognition of one’s ...
(Date:7/21/2017)... ... July 21, 2017 , ... The Margarian Law Firm has filed a ... ginger ale for allegedly containing no ginger. Dr. Pepper produces the “Canada Dry” brand ... Gegham Margaryan alleges Canada Dry Ginger Ale claims on its bottle that it is ...
(Date:7/21/2017)... ... July 21, 2017 , ... MedMatchPlus+ has launched ... of acceptance to a residency in a United States hospital. Being accepted into ... U.S. , According to data released by the ECFMG®, every year, 50 percent ...
(Date:7/21/2017)... (PRWEB) , ... July 21, 2017 , ... West Dermatology ... Tuantu Doan Vu, PA-C. Beginning July 17, 2017, Ms. Vu will join West Dermatology’s ... years of experience in dermatology, skin cancer , and more. She graduated from ...
(Date:7/21/2017)... ... 21, 2017 , ... How physicians and athletic trainers assess ... researchers presenting their work at the American Orthopaedic Society for Sports Medicine’s ... the patterns of change in concussion symptom presentation, diagnostic tools used and length ...
Breaking Medicine News(10 mins):
(Date:7/19/2017)... RALEIGH, N.C. , July 19, 2017  Mako ... Veteran Affairs, and the Military Family Assistance Fund (MFA) ... Louisiana to visit with their families one ... the funding to coordinate the travel and logistics needed ... supporting our deployed soldiers and their families. We just ...
(Date:7/14/2017)... 13, 2017 It should come as no surprise ... is in the midst of a crippling opioid epidemic. According ... the number of overdose deaths from opiate-based medications has quadrupled, ... a million dead from 2001 to 2015". During this time, ... has similarly quadrupled, drawing a compelling link between prescription and ...
(Date:7/12/2017)... CarpalAID is a revolutionary new product that relieves painful carpal tunnel ... syndrome affects more than 8 million people a year. Women suffer ... common methods of treating CTS are painful surgery, the use of ... ... is a clear patch worn on the palm of the hand. ...
Breaking Medicine Technology: