Navigation Links
Scientists Create Autism-Like Traits in Mice

MONDAY, March 21 (HealthDay News) -- Scientists report that mutating a single gene produced mice with two of the most common autism traits, a finding they say could one day lead to the development of drugs to treat autism.

Currently, there are no effective drugs to treat the disorder.

Mutating the shank3 gene led to compulsive repetitive behavior and avoidance of social interaction in the mice, apparently caused by impaired communication between brain cells, said the researchers at Duke University and the McGovern Institute for Brain Research at the Massachusetts Institute of Technology.

The shank3 gene has been implicated in human autism.

The study was published online March 20 in Nature.

"We now have a very robust model with a known cause for autistic-like behaviors," senior author Guoping Feng, a professor of brain and cognitive sciences at MIT, said in a McGovern Institute news release. "We can figure out the neural circuits responsible for these behaviors, which could lead to novel targets for treatment."

The genetically altered mice also provide a way to assess experimental autism drugs before they're tested in humans.

Scientists acknowledge that research involving animals often fails to result in beneficial treatments for humans.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about autism.

-- Robert Preidt

SOURCE: McGovern Institute for Brain Research, news release, March 20, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Scientists find candidate for new TB vaccine
2. Scientists find a key to maintaining our DNA
3. Scientists ID possible biomarker to gauge Alzheimers prognosis, effect of therapies
4. Scientists identify molecule that can increase blood flow in vascular disease
5. Nottingham scientists identify trigger in cat allergy
6. MIT scientists identify new H1N1 mutation that could allow virus to spread more easily
7. Scripps Research and MIT scientists discover class of potent anti-cancer compounds
8. Scientists find key mechanism of childhood respiratory disease
9. New weight loss discovery by Harvard scientists moves us closer to the Pill for obesity
10. Scientists Link 13 New Gene Regions to Heart Disease Risk
11. Scientists Use Stem Cells, Skin Cells to Create Brain Cells Lost to Alzheimers
Post Your Comments:
(Date:11/26/2015)... ... November 26, 2015 , ... PRMA Plastic Surgery is updating their ... surgeons performed their 6,000th free flap breast reconstruction surgery! , “What an accomplishment for ... excited to rebuild lives and it’s an honor to have served all of these ...
(Date:11/26/2015)... ... November 26, 2015 , ... Pixel ... self-animating trailer titles with ProTrailer: Vintage. This newly styled ProTrailer pack comes with ... work with any font, giving users limitless opportunities to stylize and create designs ...
(Date:11/26/2015)... ... 26, 2015 , ... Indosoft Inc., developer and distributor of the world-class Asterisk ... system efficiency and reliability. , The new Q-Suite 6 platform is based on the ... locking itself into a specific piece of software for many key components of the ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... all, Water For Empowerment ™ attracts volunteers together who want to combine ... empowering women as key stakeholders in the process. The non-profit launched its first ...
(Date:11/25/2015)... ... November 25, 2015 , ... Finnleo, a leader in ... on several models of traditional and far-infrared saunas. , For traditional saunas, ... the most traditional Finnish sauna wood, and Finnleo uses only European Grade A Nordic ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... --> --> Juntendo University Hospital ... weighting of MRI for patients with Multiple Sclerosis (MS) ... with SyntheticMR in order to use SyMRI in clinical research ... generate multiple contrast images from a single scan and adjust ... it possible to both fine tune images and recreate additional ...
(Date:11/26/2015)... ) has ... Future Horizons and Growth Strategies in the ... Shares, Country Segment Forecasts, Competitive Intelligence, Emerging ... --> ) has announced the ... and Growth Strategies in the French Drugs ...
(Date:11/26/2015)... 26, 2015 Research and Markets ( ... Wound Care Market by Type (Dressings, Therapy Devices, Active ... Facility, Out-Patient Facility), and Geography - Global Forecast to ... --> --> The purpose of ... forecast of the global advanced wound care market. It ...
Breaking Medicine Technology: