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Scientist at The Fienstein Instute for Medical Research Discovers Quitting Smoking Promotes Anti-Inflammatory Response
Date:8/27/2009

Christine Metz, PhD, is a scientist at The Feinstein Institute for Medical Research who is trying to identify some of the factors that play into a smoker's decision to quit.

Manhasset, NY (Vocus) August 27, 2009 -- If you asked a hundred smokers how they quit - or why they couldn't - you may get an equal number of different answers. Christine Metz, PhD, is a scientist at The Feinstein Institute for Medical Research who is trying to identify some of the factors that play into a smoker's decision to quit.

In collaboration with the Center for Tobacco Control of the North Shore-LIJ Health System, she is examining the effect of smoking cessation on inflammatory responses in female smokers at risk for cardiovascular disease. The grant, funded by the American Heart Association, could lead to improved understanding of the smoking cessation process and the development of more effective smoking cessation programs. Heart disease is the number one killer in women, and behavioral changes can go a long way to prevent many of these deaths. Smoking is a major risk factor. Smoking, Dr. Metz and others have shown, triggers the release of a cascade of inflammatory mediators that can, in turn, increase a person's chances of developing heart disease. Here is how the story unfolds. Smoking is associated with an elevation of inflammatory substances in the body, including tumor necrosis factor, tumor necrosis factor receptors and C-reactive protein (CRP) -- major markers of inflammation. Elevated levels of these mediators suggest that inflammation is brewing somewhere in the body, Dr. Metz said.
   
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Scientist at The Fienstein Instute for Medical Research Discovers Quitting Smoking Promotes Anti-Inflammatory Response
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